5 unknown. 5 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Unknown 5 |
| Phase 1 | 3 | Unknown 3 |
Follow B-cell Chronic Lymphocytic Leukemia: new trials by email Literature Review of B-cell Chronic Lymphocytic Leukemia trials Research Report on B-cell Chronic Lymphocytic Leukemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma anti-CD19 CAR-T, Fludarabine, Cyclophosphamide - Hematopoietic/Lymphoid Cancer, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Unknown | The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine | 20 | 2016-02-01 | 2017-03-16 |
| Pilot Study of Autologous T Lymphocytes With ADCC in Patients With CD20-Positive B-Cell Malignancies T-cell therapy + Rituximab + IL-2 - B-Cell Chronic Lymphocytic Leukemia, Non-Hodgkin's Lymphoma | Phase 1 / Phase 2 | Unknown | National University Hospital, Singapore | 18 | 2014-12-01 | 2016-06-22 |
| Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy anti-CD20-CAR vector-transduced autologous T cells, genetically engineered lymphocyte therapy - Hematopoietic/Lymphoid Cancer, Adult Acute Lymphoblastic Leukemia in Remission | Phase 1 / Phase 2 | Unknown | Chinese PLA General Hospital | 50 | 2013-01-01 | 2015-09-29 |
| Interventional Study on Pentostatin, Cyclophosphamide and Rituximab in Indolent B-Cell Non-Hodgkin-Lymphoma (B-NHL) Cyclophosphamide, Pentostatin, Rituximab - Immunocytoma/Morbus Waldenström, B-Cell Non-Hodgkin's Lymphoma | Phase 2 | Unknown | Heidelberg University | 185 | 2005-02-01 | 2009-06-25 |
| Study of Subcutaneous Campath-1H in Patients With B-Cell CLL and Residual Disease After Chemotherapy Alemtuzumab (Campath-1H) - B-Cell Chronic Lymphocytic Leukemia | Phase 2 | Unknown | Chronic Lymphocytic Leukemia Research Consortium | 31 | 2003-12-01 | 2008-12-03 |
Leukemia, Lymphocytic, Chronic, B-Cell (5) · Hematologic Neoplasms (2) · Lymphoma, Follicular (2) · Lymphoma, Large B-Cell, Diffuse (2) · Lymphoma, Mantle-Cell (2) · Bronchiolitis Obliterans Syndrome (1) · Leukemia (1) · Leukemia, Prolymphocytic (1) · Lymphoma, B-Cell (1) · Lymphoma, B-Cell, Marginal Zone (1) · Lymphoma, Non-Hodgkin (1)
Chronic Disease (5) · Disease Attributes (5) · Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Immune System Diseases (5) · Immunoproliferative Disorders (5) · Leukemia, B-Cell (5) · Leukemia, Lymphoid (5) · Lymphatic Diseases (5) · Lymphoproliferative Disorders (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Leukemia (4)
Cyclophosphamide (2) · Rituximab (2) · Alemtuzumab (1) · Immunotherapy, Adoptive (1) · Interleukin-2 (1) · Pentostatin (1) · fludarabine (1)
Chinese PLA General Hospital (1) · Chronic Lymphocytic Leukemia Research Consortium (1) · Heidelberg University (1) · National University Hospital, Singapore (1) · The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine (1)
China (2) · Singapore (1) · United States (1)
Anthony D Ho, Ph.D., Prof. (1) · Michelle Poon, MBBS, MRCP (1) · Thomas Kipps, MD, PhD (1) · Yeh Ching Linn, MBBS, MRCP (1) · Zhi Cheng, M.D. (1)
PMID 25444722, PMID 29263894, PMID 34515338
2014 (1)