12 recruiting, 4 completed, 3 not yet recruiting, 2 active not recruiting. 13 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Recruiting 7, Completed 2, Not yet recruiting 2, Active not recruiting 1, Unknown 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Natural History Study for Patients With Nemaline Myopathy in Belgium Motor Function Assessments, Syde, Respiratory Assessments - Nemaline Myopathy | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Liege | 10 | 2026-08-01 | 2026-03-25 |
| Digital Monitoring of Upper Limb Function in Non-Ambulant DMD Performance of the Upper Limb (PUL) Test, Brook test, Dynamometric measurements of muscle strength - Duchenne Muscular Dystrophy (DMD) | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire de Liege | 50 | 2026-07-30 | 2026-06-23 |
| SMAdult - Monitoring of Movement on Spinal Muscular Atrophy wearable sensors - Spinal Amyotrophy | Not applicable | Recruiting | Centre Hospitalier Universitaire de Liege | 60 | 2026-07-17 | 2026-10-26 |
| Study to Evaluate the Feasibility of Syde® Digital Endpoints for Monitoring Patients With Progressive Supranuclear Palsy - Richardson Syndrome (PSP-R) Progressive Supranuclear Palsy- Richardson Syndrome (PSP-R) | Not yet recruiting | SYSNAV | 30 | 2026-05-01 | 2026-04-22 | |
| Investigating Specific Gait Patterns in Individuals Living With Multiple Sclerosis Multiple Sclerosis, Healthy Adult | Recruiting | SYSNAV | 30 | 2026-03-16 | 2026-03-23 | |
| Prospective Longitudinal Multicentric Study to Measure Limb Movement in Patients With FGFR3-related Skeletal Dysplasia Achondroplasia, Hypochondroplasia | Recruiting | SYSNAV | 140 | 2026-02-06 | 2026-09-23 | |
| Active NBS Study: Decentralised Monitoring Motor Development in Children With Duchenne Muscular Dystrophy or Spinal Muscular Atrophy Identified by Newborn Screening MAIJU, Syde, Questionnaires - Spinal Muscular Atrophy (SMA), Duchenne Muscular Dystrophy (DMD) | Not applicable | Recruiting | Centre Hospitalier Universitaire de Liege | 100 | 2025-12-01 | 2025-12-16 |
| Gait Analysis Parameter and Upper Limb Evaluation in Control Participants Syde, Post-recording questionnaire - Healthy Participants | Not applicable | Recruiting | Centre Hospitalier Universitaire de Liege | 200 | 2025-09-24 | 2026-05-19 |
| Pilot Study to Identify and Validate Digital Biomarkers in Osteoarthritis of the Knee Syde, The Self-Paced 40-meter Walk Test (SPWT), 30-second chair stand test (30s-CST) - Osteoarthritis of the Knee | Not applicable | Completed | Centre Hospitalier Universitaire de Liege | 43 | 2025-05-14 | 2026-03-24 |
| Prospective Longitudinal Multicentric Study to Evaluate Syde® Digital Endpoints in Healthy Adults Healthy Adults | Active not recruiting | SYSNAV | 129 | 2025-01-20 | 2026-01-29 | |
| Prospective Longitudinal Monocentric Study to Evaluate the Syde® Digital Endpoint in Patients With Multiple Sclerosis Digital HealthTechnology - Multiple Sclerosis | Terminated | SYSNAV | 86 | 2024-04-25 | 2025-12-15 | |
| Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT) - Neuromuscular Diseases, Obesity (Disorder) | Not applicable | Recruiting | Centre Hospitalier Universitaire de Liege | 300 | 2024-03-29 | 2025-08-22 |
| Exploratory Study on Predicting CIDP Patients' Decline During IV Immunoglobulin Treatment Adaptation Feasibility. Actimyo - Chronic Inflammatory Demyelinating Polyneuropathy | Recruiting | Centre Hospitalier Universitaire de Liege | 40 | 2023-08-28 | 2025-02-12 | |
| Holter of Movement in Patients With Amyotrophic Lateral Sclerosis. Actimyo - Amyotrophic Lateral Sclerosis | Recruiting | Centre Hospitalier Universitaire de Liege | 30 | 2023-05-01 | 2025-05-19 | |
| Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy (GRAND CANYON) Sevasemten 10 mg, Sevasemten 5 mg, Sevasemten 12.5 mg - Becker Muscular Dystrophy | Phase 2 | Completed | Edgewise Therapeutics, Inc. | 244 | 2022-11-10 | 2026-09-21 |
| Controlled Study of Upper and Lower Limb Movements in Patients Patients with Pathologies That Have an Impact on Ambulation or Motor Function ActiMyo®/Syde® - Neuromuscular Diseases | Not applicable | Recruiting | Laurent Servais | 200 | 2022-08-24 | 2025-02-12 |
| Natural History Study for Patients With Angelman Syndrome Angelman Syndrome | Recruiting | Centre Hospitalier Universitaire de Liege | 30 | 2021-10-10 | 2025-05-20 | |
| Holter of Movement in Patients with Multiple Sclerosis in Uncontrolled Environment. Actimyo - Multiple Sclerosis | Not applicable | Active not recruiting | Centre Hospitalier Universitaire de Liege | 80 | 2021-03-09 | 2025-02-12 |
| Holter of Movement in Patients with Multiple Sclerosis in Controlled Environment. Actimyo°, IMU - Multiple Sclerosis | Not applicable | Completed | Laurent Servais | 21 | 2021-02-04 | 2025-02-12 |
| Continuous Measurement of Activity in Patients With Muscle Pathology and in Control Subjects. ActiSLA Part. Actimyo° - Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | Centre Hospitalier Universitaire de Liege | 45 | 2020-09-25 | 2025-12-05 |
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Muscular Dystrophy, Duchenne (5) · Multiple Sclerosis (4) · Muscular Atrophy, Spinal (3) · Amyotrophic Lateral Sclerosis (2) · Charcot-Marie-Tooth Disease (2) · Muscular Dystrophy, Facioscapulohumeral (2) · Myotonic Dystrophy (2) · Neuromuscular Diseases (2) · Achondroplasia (1) · Angelman Syndrome (1) · Huntington Disease (1) · Hypochondroplasia (1) · Lambert-Eaton Myasthenic Syndrome (1) · Motor Neuron Disease (1) · Myasthenia Gravis (1)
Surveys and Questionnaires (1) · Vital Capacity (1) · Walk Test (1)
Belgium (18) · France (7) · Egypt (3) · United Kingdom (3) · Italy (2) · Romania (2) · United States (2) · Australia (1) · Czechia (1) · Denmark (1) · Germany (1) · Hungary (1) · Israel (1) · Netherlands (1) · New Zealand (1)
Laurent Servais, MD (4) · Margaux Poleur, MD (3) · Laurent Servais, MD, PhD (2) · Ahmed Elnemr, MD (1) · Genevieve Baujat (1) · Joanne Donovan, MD, PhD (1) · Laura Vanden Brande (1) · Margaux Poleur (1) · Margaux Poleur, Dr (1) · Patrick Vermersch (1) · Roxana D. Dreghici (1) · Shotaro Tachibana (1)