3 completed, 1 unknown, 1 withdrawn. 3 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects leramistat 40mg, Itraconazole 200 mg, Phenytoin 100 Mg Oral Capsule - Pharmacokinetics | Phase 1 | Unknown | Modern Biosciences Ltd | 48 | 2024-04-08 | 2024-08-09 |
| A Study to Investigate Leramistat in Patients With IPF Leramistat, Placebo - Idiopathic Pulmonary Fibrosis | Phase 2 | Withdrawn | Modern Biosciences Ltd | 2023-08-30 | 2025-04-09 | |
| Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA MBS2320 5 mg, MBS2320 20 mg, MBS2320 40 mg - Rheumatoid Arthritis | Phase 2 | Completed | Modern Biosciences Ltd | 248 | 2022-08-29 | 2025-04-24 |
| Safety, Tolerability and Efficacy of MBS2320 in Patients With Rheumatoid Arthritis MBS2320, Placebo - Rheumatoid Arthritis | Phase 2 | Completed | Modern Biosciences Ltd | 121 | 2017-05-30 | 2019-08-14 |
| Safety and Tolerability Study of MBS2320 in Healthy Subjects and Subjects With Rheumatoid Arthritis MBS2320, Placebo, Methotrexate - Arthritis, Rheumatoid | Phase 1 | Completed | Modern Biosciences Ltd | 105 | 2015-07-01 | 2017-03-28 |
Arthritis, Rheumatoid (3) · Idiopathic Pulmonary Fibrosis (1) · Joint Diseases (1) · Musculoskeletal Diseases (1)
Itraconazole (1) · Methotrexate (1) · Phenytoin (1) · Simvastatin (1) · upadacitinib (1)
United Kingdom (3) · Bosnia and Herzegovina (1) · Bulgaria (1) · Chile (1) · Czechia (1) · France (1) · Georgia (1) · Germany (1) · Greece (1) · Guatemala (1) · Hungary (1) · Israel (1) · Italy (1) · Mexico (1) · Moldova (1)
Inga Bodrug, MD (1) · Jim Bush, MBChB,PhD (1)
2015 (1), 2016 (1), 2023 (1)