2 terminated, 1 completed, 1 withdrawn. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Terminated 2, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| XmAb18968 (CD3-CD38) in Relapsed or Refractory Acute Leukemia and T Cell Lymphoblastic Leukemia XmAb18968 - Dose level -1, XmAb18968 - Dose level 0 (starting dose), XmAb18968 - Dose level 1 - Acute Myeloid Leukemia, T Cell Acute Lymphoblastic Leukemia | Phase 1 | Terminated | Ehab L Atallah | 22 | 2022-02-02 | 2025-05-08 |
| Standard Maintenance POMP/D Plus Ixazomib Maintenance Therapy in Adult Patients With Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma or Mixed Phenotype Acute Leukemia in Complete Remission (CR) Ixazomib - Acute Lymphoblastic Leukemia in Complete Remission, Lymphoblastic Lymphoma in Complete Remission | Phase 1 | Withdrawn | Ehab L Atallah | 2017-06-29 | 2018-02-15 | |
| Hypomethylating Properties of Freeze-dried Black Raspberries (BRB) in Patients With Myelodysplastic Syndrome or Myelodysplastic Syndrome/Myeloproliferative Neoplasm (MDS/MPN) Freeze-Dried Black Raspberry Powder - Myelodysplastic Syndromes | Phase 2 | Completed | Ehab L Atallah | 23 | 2017-06-05 | 2022-11-04 |
| Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia MLN9708, Vincristine, Doxorubicin - Relapsed or Refractory Acute Lymphoblastic Leukemia, Relapsed or Refractory Lymphoblastic Lymphoma | Phase 1 | Terminated | Ehab L Atallah | 5 | 2013-06-01 | 2020-01-22 |
Leukemia, Biphenotypic, Acute (2) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Leukemia, Myeloid, Acute (1) · Myelodysplastic Syndromes (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Recurrence (1)
ixazomib (2) · Calcium Dobesilate (1) · Dexamethasone (1) · Doxorubicin (1) · Vincristine (1) · liposomal doxorubicin (1)
United States (4)
Ehab Atallah, MD (3)