9 completed, 1 active not recruiting, 1 terminated. 5 Phase 2, 3 Phase 3, 2 Phase 1, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Active not recruiting 1 |
| Phase 3 | 3 | Completed 2, Terminated 1 |
| Phase 1 | 2 | Active not recruiting 1, Completed 1 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab Pelareorep, Atezolizumab, Gemcitabine and nab-paclitaxel - Anal Cancer Metastatic, Squamous Cell Carcinoma of the Anus Stage Unspecified | Phase 1 / Phase 2 | Active not recruiting | Oncolytics Biotech | 122 | 2021-10-27 | 2026-05-19 |
| 2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapy Irinotecan Liposomal Injection [Onivyde] - Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer | Phase 3 | Completed | AIO-Studien-gGmbH | 151 | 2018-03-31 | 2025-04-17 |
| Role of PRoactivE Coaching on PAtient REported Outcome in Advanced or Metastatic RCC Treated With Sunitinib or a Combination of Pembrolizumab + Axitinib or Avelumab + Axitinib in First Line Therapy Concomitant coaching - Renal Cell Carcinoma, Metastatic, Renal Cell Cancer, Recurrent | Phase 3 | Terminated | AIO-Studien-gGmbH | 121 | 2017-01-18 | 2025-02-14 |
| Anterior Pelvic Prolapse Reconstruction With TiLOOP® PRO A Polypropylene Mesh TiLOOP® PRO Plus A - Cystocele, Uterine Prolapse | Not applicable | Completed | pfm medical gmbh | 54 | 2016-02-01 | 2019-10-23 |
| Treatment of Newly Diagnosed Moderate or Severe Chronic Graft-versus-host Disease With Prednisone and Everolimus PredEver - Chronic Graft-versus-host Disease | Phase 2 | Completed | Universitätsklinikum Hamburg-Eppendorf | 38 | 2013-03-06 | 2020-04-02 |
| Efficacy of Medical Treatment With SOM230 LAR in Patients With Primary Inoperable Thymoma and/or With Local Recurrent Thymoma to Reduce Tumor Size SOM230 LAR - Primary Inoperable Thymoma, Local Recurrent Thymoma | Phase 2 | Completed | Prof. Dr. Berthold Schalke | 16 | 2012-03-01 | 2018-02-05 |
| Assessment of Efficacy of Zoledronic Acid in the Treatment of Bone Marrow Edema Syndrome Aclasta, Placebo - Bone Marrow Edema | Phase 3 | Completed | Wuerzburg University Hospital | 48 | 2011-05-01 | 2024-08-13 |
| Compliance: Role Emerges for Success in Chronic Myelogenous Leukaemia (CML): Evaluation aND Optimisation compliance supporting measures - Chronic Myelogenous Leukemia (CML) | Phase 4 | Completed | Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH | 104 | 2010-10-01 | 2019-12-20 |
| Anterior Pelvic Prolapse Reconstruction With TiLOOP® Total 6 surgical mesh implantation (TiLOOP® Total 6) - Cystocele, Uterine Prolapse | Completed | pfm medical gmbh | 292 | 2010-04-01 | 2019-02-04 | |
| The Impact of Deferasirox on Non-Alcoholic-Steatohepatitis Exjade - Non-alcoholic Steatohepatitis, Increased Iron Storage / Disturbed Distribution | Phase 1 / Phase 2 | Completed | Crolll Gmbh | 5 | 2010-03-01 | 2012-07-20 |
| Antiangiogenic Treatment of Hepatocellular Cancer With Bevacizumab and RAD001 Everolimus, Bevacizumab - Hepatocellular Carcinoma | Phase 2 | Completed | Gerhard Treiber | 33 | 2008-10-01 | 2012-04-30 |
Cystocele (2) · Prolapse (2) · Uterine Prolapse (2) · Bronchiolitis Obliterans Syndrome (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Renal Cell (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Liver Neoplasms (1) · Neoplasm Metastasis (1) · Non-alcoholic Fatty Liver Disease (1) · Pancreatic Neoplasms (1) · Patient Compliance (1) · Philadelphia Chromosome (1) · Recurrence (1)
130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · Bevacizumab (1) · Deferasirox (1) · Everolimus (1) · Gemcitabine (1) · Octreotide (1) · Zoledronic Acid (1) · atezolizumab (1) · irinotecan sucrosofate (1) · pasireotide (1) · reolysin (1) · trifluridine tipiracil drug combination (1)
Germany (11)
Andreas Hochhaus, Professor, MD (1) · Berthold Schalke, Prof. Dr. (1) · Gerhard Treiber, PD Dr. (1) · Gerhard Treiber, PD Dr. med. (1) · Manfred P. Lutz, Prof. Dr. (1) · Rainer Meffert, Prof. Dr. (1)
PMID 19192962, PMID 26781262, PMID 28959063, PMID 40696453, PMID 41087530
2016 (1)