2 active not recruiting, 2 not yet recruiting, 1 unknown. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Active not recruiting 2, Not yet recruiting 2, Unknown 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1 First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors CRPA1A2 - Lung Cancer (Locally Advanced or Metastatic), Esophagus Cancer | Phase 1 | Not yet recruiting | Corregene Biotechnology Co., Ltd | 192 | 2026-05-29 | 2026-05-13 |
| Treatment of Patients With Advanced Solid Tumors Using CRTKVA11-03 TCR-T Cell Injection CRTKVA11-03 TCR-T Cell Injection - Advanced Solid Tumors | Phase 1 | Active not recruiting | Corregene Biotechnology Co., Ltd | 6 | 2026-03-26 | 2026-09-17 |
| KRAS-Specific Autologous TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors KRAS-specific Autologous TCR-T cell injection - Colorectal, Pancreatic | Phase 1 | Active not recruiting | Corregene Biotechnology Co., Ltd | 8 | 2025-02-18 | 2026-03-25 |
| CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers CRTE7A2-01 TCR-T cell therapy - Cervical Cancer, Anal Cancer | Phase 1 | Not yet recruiting | Corregene Biotechnology Co., Ltd | 24 | 2024-04-15 | 2024-04-10 |
| CRTE7A2-01 TCR-T Cell for HPV-16 Positive Advanced Cervical, Anal, or Head and Neck Cancers Fludarabine + Cyclophosphamide, Interleukin-2, CRTE7A2-01 TCR-T Cell - Cervical Cancer, Anal Cancer | Phase 1 | Unknown | Corregene Biotechnology Co., Ltd | 12 | 2022-07-17 | 2022-06-28 |
Head and Neck Neoplasms (3) · Anus Neoplasms (2) · Uterine Cervical Neoplasms (2) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Esophageal Neoplasms (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1)
Cyclophosphamide (1) · Interleukin-2 (1) · fludarabine (1)
China (4)