2 completed, 2 recruiting, 1 no longer available, 1 withdrawn. 3 Phase 3, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age (taurolidine and heparin) catheter lock solution, Standard of Care - Catheter-Related Infections | Phase 4 | Recruiting | CorMedix Therapeutics | 36 | 2025-07-08 | 2026-09-25 |
| Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults And Adolescent Participants Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC) (taurolidine and heparin) catheter lock solution, Heparin - Central Line Associated Blood Stream Infections (CLABSI) | Phase 3 | Recruiting | CorMedix Therapeutics | 200 | 2025-05-14 | 2026-09-25 |
| Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection Neutrolin, Heparin - Kidney Failure, Chronic, Catheter-Related Infections | Phase 3 | Completed | CorMedix Therapeutics | 806 | 2015-12-01 | 2025-02-25 |
| Efficacy and Safety of Deferiprone in Patients With Chronic Kidney Disease Undergoing a Cardiac Catheterization and Receiving Contrast Agent deferiprone, Placebo - Acute Kidney Injury | Phase 3 | Withdrawn | CorMedix Therapeutics | 2012-01-01 | 2020-08-24 | |
| Deferiprone for the Prevention of Contrast-Induced Acute Kidney Injury CRMD-001-Deferiprone, Placebo - Contrast-Induced Acute Kidney Injury | Phase 2 | Completed | CorMedix Therapeutics | 60 | 2010-06-01 | 2011-06-27 |
| Expanded Access Program for Patients at Risk for Catheter-related Infections Who Are Not Eligible for DefenCath® Clinical Trials Taurolidine and Heparin - Catheter-related Bloodstream Infection | No longer available | CorMedix Therapeutics | 2026-07-01 |
Acute Kidney Injury (2) · Catheter-Related Infections (2) · Kidney Failure, Chronic (1)
Heparin (4) · taurolidine (4) · Citric Acid (1) · Deferiprone (1) · Standard of Care (1)
United States (4) · Turkey (Türkiye) (1)
Antony Pfaffle, MD (1) · Peter A. McCullough, MD, MPH (1)