5 completed, 2 terminated, 1 active not recruiting, 1 unknown. 3 Phase 2, 2 Not applicable, 2 Phase 1, 2 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 4 | 1 | Active not recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects Secretin (human synthetic) - ChiRhoClin - Exocrine Pancreatic Insufficiency, Chronic Pancreatitis | Phase 4 | Active not recruiting | Mayo Clinic | 24 | 2026-03-11 | 2026-10-26 |
| Recurrent Abdominal Pain and Exocrine Pancreatic Insufficiency synthetic human secretin - Abdominal Pain, Irritable Bowel Syndrome | Phase 3 | Terminated | Orlando Health, Inc. | 27 | 2022-01-28 | 2024-04-03 |
| Secretin for Acute Pancreatitis Secretin - Pancreatitis, Acute | Phase 2 | Unknown | ChiRhoClin, Inc. | 40 | 2018-10-01 | 2019-04-10 |
| MRCP: A Reliable, Non Invasive Method for Staging Chronic Pancreatitis in Pediatrics Secretin - Healthy Volunteers | Not applicable | Completed | Children's Hospital Medical Center, Cincinnati | 57 | 2016-08-10 | 2020-08-07 |
| Efficacy of Secretin MRCP in the Diagnosis and Follow up of Auto Immune Pancreatitis Cellular Diagnosis, Pancreatic Cancer, Autoimmune Pancreatitis | Withdrawn | Johns Hopkins University | 2013-02-01 | 2019-01-10 | ||
| Secretin Infusion for Pain Due to Chronic Pancreatitis Human Secretin - Chronic Pancreatitis | Phase 1 / Phase 2 | Completed | ChiRhoClin, Inc. | 12 | 2010-12-01 | 2016-03-09 |
| Screening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study) Early Pancreatic Neoplasia, Familial Pancreatic Neoplasia | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 631 | 2008-06-01 | 2018-09-07 | |
| A Study of Synthetic Human Secretin (ChiRhoStim®) Administered Intravenously to Stimulate Exocrine Pancreas Fluid Secretion for Collection Via Endoscope and Laboratory Analysis of DNA Markers ChiRhoStim, Placebo - Pancreatic Disease | Phase 3 | Completed | ChiRhoClin, Inc. | 64 | 2007-10-01 | 2011-12-06 |
| Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic Adenocarcinoma Synthetic Human Secretin - Pancreatic Cancer | Phase 1 / Phase 2 | Terminated | Mayo Clinic | 4 | 2006-11-01 | 2013-06-24 |
| Endoscopic Ultrasound Compared With Pancreatic Function Testing for Diagnosis of Chronic Pancreatitis EUS - Chronic Pancreatitis | Not applicable | Completed | The Cleveland Clinic | 70 | 2005-05-01 | 2016-02-03 |
Pancreatitis, Chronic (3) · Pancreatic Neoplasms (2) · Abdominal Pain (1) · Autoimmune Pancreatitis (1) · Diabetes Mellitus (1) · Disease (1) · Exocrine Pancreatic Insufficiency (1) · Irritable Bowel Syndrome (1) · Pancreatic Diseases (1) · Pancreatitis (1) · Peutz-Jeghers Syndrome (1)
Secretin (6)
United States (10)
Andrew Trout, MD (1) · Atif Zaheer, M.D. (1) · Frank Burton, M.D. (1) · Maisam Abu-El-Haija, MD (1) · Marcia Irene F. Canto, MD, MHS (1) · Naoki Takahashi, M.D. (1) · Samuel Han, MD (1) · Timothy B Gardner, M.D. (1) · Timothy B Gardner, MD (1)