6 completed, 1 not yet recruiting, 1 terminated, 1 unknown. 6 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 5, Unknown 1 |
| Phase 2 | 4 | Completed 2, Not yet recruiting 1, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome SRX246, Placebo - Aggressive Behavior in Fragile X Syndome | Phase 2 | Not yet recruiting | Azevan Pharmaceuticals | 80 | 2026-03-01 | 2026-01-09 |
| Effects of SRX246 on an Experimental Model of Fear and Anxiety in Humans SRX246, Placebo - Fear, Anxiety | Phase 1 | Unknown | Azevan Pharmaceuticals | 36 | 2017-02-03 | 2019-06-10 |
| Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD SRX246, Placebo - PTSD | Phase 2 | Terminated | Azevan Pharmaceuticals | 33 | 2016-12-01 | 2021-11-01 |
| Tolerability, Safety, and Activity of SRX246 in Irritable Subjects With Huntington's Disease SRX246, Placebo - Irritable Mood, Huntington's Disease | Phase 2 | Completed | Azevan Pharmaceuticals | 106 | 2016-05-10 | 2023-07-20 |
| Safety, Tolerability and Activity of SRX246 in Adults With Intermittent Explosive Disorder SRX246, Placebo - Intermittent Explosive Disorder | Phase 1 / Phase 2 | Completed | Azevan Pharmaceuticals | 97 | 2014-05-01 | 2023-07-21 |
| Multiple Dose Safety Study of SRX246 Capsules in Healthy Volunteers SRX246 - Healthy | Phase 1 | Completed | Azevan Pharmaceuticals | 24 | 2010-03-01 | 2010-07-20 |
| Study of SRX246 Capsules in Healthy Adult Volunteers SRX246, Placebo - Healthy | Phase 1 | Completed | Azevan Pharmaceuticals | 49 | 2009-05-01 | 2010-03-17 |
| Multiple Dose Safety Study of SRX251 Capsules in Healthy Volunteers SRX251 - Healthy | Phase 1 | Completed | Azevan Pharmaceuticals | 50 | 2007-09-01 | 2008-03-13 |
| Safety Study of SRX251 Capsules in Healthy Female Volunteers SRX251 - Healthy | Phase 1 | Completed | Azevan Pharmaceuticals | 77 | 2007-04-01 | 2008-03-13 |
Aggression (2) · Anxiety Disorders (1) · Disruptive, Impulse Control, and Conduct Disorders (1) · Fragile X Syndrome (1) · Huntington Disease (1) · Psychomotor Agitation (1) · Self-Injurious Behavior (1) · Stress Disorders, Post-Traumatic (1)
SRX246 (7)
United States (9)
Benno G Roesch, MD (3) · Stephan A Bart, MD (1)
U44NS090616 (1)