11 completed, 2 no longer available. 10 Phase 2, 3 Phase 1.
By phase and status
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
Study to Evaluate the Safety, Phage Kinetics, and Efficacy of Inhaled AP-PA02 in Subjects With Non-Cystic Fibrosis Bronchiectasis and Chronic Pulmonary Pseudomonas Aeruginosa Infection AP-PA02, Placebo - Non-cystic Fibrosis Bronchiectasis, Pseudomonas Aeruginosa | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 48 | 2023-01-10 | 2026-01-05 |
Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia AP-SA02, Placebo - Bacteremia, Staphylococcus Aureus | Phase 1 / Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 56 | 2022-04-26 | 2026-03-23 |
Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aeruginosa Lung Infections and Cystic Fibrosis AP-PA02, Placebo - Cystic Fibrosis, Pseudomonas Aeruginosa | Phase 1 / Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 29 | 2020-12-22 | 2024-01-31 |
A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects C16G2, Placebo - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 20 | 2017-07-07 | 2022-12-22 |
A Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Dental Strip Application C16G2 Strip, Placebo Strip - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 30 | 2017-02-09 | 2022-12-22 |
A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects C16G2 Varnish, Placebo Varnish - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 33 | 2017-01-27 | 2022-12-29 |
Ascending Dose Study of the Safety of AB-SA01 When Topically Applied to Intact Skin of Healthy Adults AB-SA01 (10^8 PFU per phage), AB-SA01 (10^9 PFU per phage), Placebo (for Cohort 10^8) - Healthy Volunteers | Phase 1 | Completed | Armata Pharmaceuticals, Inc. | 12 | 2016-05-01 | 2016-08-31 |
Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects C16G2 Gel, Placebo - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 135 | 2015-11-01 | 2019-08-01 |
Study to Evaluate the Safety and Microbiology of C16G2 in Adolescent and Adult Dental Subjects C16G2, Placebo - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 64 | 2015-07-01 | 2019-08-01 |
Phase 2, Open-Label Study for Safety, Microbiology and PK of Single or Multiple Oral C16G2 Gel Doses C16G2 - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 52 | 2014-10-01 | 2019-08-01 |
Phase 2, Safety & Microbiology Study of C16G2 in Multiple Oral Gel &/or Mouth Rinse Doses to Healthy Adults C16G2 Rinse, Placebo, C16G2 Gel - Dental Caries | Phase 2 | Completed | Armata Pharmaceuticals, Inc. | 60 | 2014-02-01 | 2019-08-01 |
Individual Patient Expanded Access for AB-PA01, an Investigational Anti-Pseudomonas Aeruginosa Bacteriophage Therapeutic AB-PA01 | | No longer available | Armata Pharmaceuticals, Inc. | | | 2019-05-29 |
Individual Patient Expanded Access for AB-SA01, an Investigational Anti-Staphylococcus Aureus Bacteriophage Therapeutic AB-SA01 | | No longer available | Armata Pharmaceuticals, Inc. | | | 2019-05-29 |
Conditions studied
Dental Caries (7) · Pseudomonas Infections (2) · Bacteremia (1) · Cystic Fibrosis (1) · Staphylococcal Infections (1)
Interventions
Antimicrobial Peptides (3)
Countries
United States (11) · Australia (1)
Top investigators
John Pittaway, DMD (3) · Adam D Marberger, DDS (1) · Adam Marberger, DDS (1) · Deborah Birx, MD (1) · Jeffrey Livezey, MD (1) · John F Pittaway, DMD (1) · Mark Wolff, DDS, PhD (1) · Mark Wolff, MD (1) · Mina Pastagia, MD, MS (1)