19 completed, 18 unknown, 6 recruiting, 3 terminated. 27 Phase 3, 12 Phase 2, 6 Phase 4, 5 Not applicable, 2 Phase 1.
Follow Vindesine: new trials by email Literature Review of Vindesine trials Research Report on Vindesine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Venetoclax Combined With Azacitidine, Chidamide, Vindesine, and Dexamethasone in Newly Diagnosed ETP-ALL Like Patients VEN (Venetoclax), Azacitidine (AZA), Chidamide - Adult T-cell Leukemia/Lymphoma | Phase 2 | Recruiting | The First Affiliated Hospital of Soochow University | 27 | 2025-09-01 | 2026-10-16 |
| FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration Luvometinib, Chemotherapeutic Agent COG-V/C Carboplatin + Vindesine, Carboplatin, Temozolomide - Low-grade Glioma, Pediatric Low-grade Gliomas | Phase 3 | Not yet recruiting | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 102 | 2025-06-30 | 2025-06-04 |
| Efficacy of Organoid-Based Chemotherapy Drug Precision Screening to Guide Treatment for Thyroid Cancer Cyclophosphamide+Pemetrexed+5-Fluorouracil, Cyclophosphamide+Doxorubicin+5-Fluorouracil, Vindesine + Cisplatin - Locally Advanced Thyroid Gland Carcinoma, Thyroid Cancer | Phase 2 | Not yet recruiting | West China Hospital | 20 | 2024-12-01 | 2024-12-03 |
| Comparing the Efficacy of VHAG and Traditional Chemotherapy Regimens in Newly Diagnosed ETP-ALL Homoharringtonine, venetoclax, Cytarabine - ETP-ALL | Phase 3 | Recruiting | First Affiliated Hospital of Zhejiang University | 81 | 2024-04-03 | 2025-02-17 |
| R-CMOP in Patients With Primary Diffuse Large B-cell Lymphoma Rituximab, Mitoxantrone hydrochloride liposome, Cyclophosphamide - Diffuse Large B-cell Lymphoma | Not applicable | Unknown | The First Affiliated Hospital with Nanjing Medical University | 30 | 2023-03-01 | 2023-03-21 |
| Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL) Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin, Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin, Vindesine, Etoposide, Ifosfamide - T-cell Lymphoblastic Lymphoma | Phase 3 | Recruiting | Children's Cancer Group, China | 200 | 2023-02-06 | 2026-03-19 |
| Zanubrutinib Combined With R-CHOP in Newly-diagnosed Intravascular Large B-cell Lymphoma Zanubrutinib, Rituximab, Cyclophosphamide - Intravascular Large B-Cell Lymphoma | Phase 2 | Unknown | Peking Union Medical College Hospital | 20 | 2021-04-01 | 2021-05-24 |
| High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) Vincristine, Carboplatin, Etoposide - High-Risk Neuroblastoma, Patient With Insufficient Response Chemoimmunotherapy | Phase 3 | Recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 800 | 2019-11-05 | 2025-06-26 |
| International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma Cyclophosphamide, Cytarabine, Dexamethasone - Lymphoblastic Lymphoma, Childhood | Phase 3 | Recruiting | University Hospital Muenster | 683 | 2019-08-23 | 2026-05-06 |
| Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017 Blinatumomab, Bortezomib, Cyclophosphamide - Acute Lymphoblastic Leukemia, Pediatric | Phase 3 | Recruiting | Martin Schrappe | 5000 | 2018-07-15 | 2025-04-06 |
| Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents Rituximab window, Additional doses of Rituximab, Cyclophosphamide - Mature B-cell Non-Hodgkin Lymphoma | Phase 3 | Active not recruiting | University Hospital Muenster | 650 | 2017-08-03 | 2026-04-30 |
| R-ACVBP and DA-EPOCH-R in Patients With Non-GCB DLBCL Rituximab, Etoposide, Doxorubicin - Lymphoma, Large B-Cell, Diffuse | Phase 3 | Unknown | Nanfang Hospital, Southern Medical University | 402 | 2017-07-27 | 2017-07-28 |
| Cinobufacini Tablets Combined With Chemotherapeutic Protocol in Treatment of Diffuse Large B Cell Lymphoma vindesine, cyclophosphamide, Epirubicin - Diffuse, Large B-Cell, Lymphoma | Phase 2 / Phase 3 | Unknown | Xinjiang Medical University | 316 | 2016-09-01 | 2017-07-17 |
| Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment Rituximab, Nelarabine, PEG-Asparaginase - Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma | Phase 3 | Completed | Goethe University | 1023 | 2016-08-01 | 2025-12-16 |
| Trial of R-GemOx Versus R-miniCHOP Regimen in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma Rituximab, Gemcitabine, Oxaliplatin - Diffuse Large B Cell Lymphoma | Phase 3 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 258 | 2016-05-01 | 2019-01-03 |
| Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell Lymphoma Chidamide, Cyclophosphamide, Epirubicin - T Cell Non-Hodgkin's Lymphoma | Phase 1 / Phase 2 | Unknown | Peking Union Medical College Hospital | 100 | 2016-03-01 | 2016-12-08 |
| LBL-2016 for Children or Adolescents in China Prednisone,Vincristine, Pegylated-asparaginase, Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, 6-mercaptopurine,Methotrexate, Dexamethasone,Vincristine, Pegylated-asparaginase, Cytarabine, Cyclophosphamide, Doxorubicin, 6-mercaptopurine - Lymphoblastic Lymphoma | Phase 3 | Active not recruiting | Children's Cancer Group, China | 150 | 2016-01-01 | 2026-03-18 |
| Haplo-identical HSCT Versus Chemotherapy for Adult Acute Lymphoblastic Leukemia Patients Haplo-identical HSCT, Chemotherapy - Acute Lymphoblastic Leukemia | Phase 3 | Completed | Peking University | 131 | 2014-07-01 | 2019-05-29 |
| Treatment of Mature B-ALL and Burkitt Lymphoma (BL) in Adult Patients. BURKIMAB-14. Rituximab, Methotrexate, Dexamethasone - Mature B-Cell Leukemia Burkitt Type, Burkitt Lymphoma (BL) | Phase 2 | Unknown | PETHEMA Foundation | 100 | 2014-01-01 | 2021-09-20 |
| GA In NEwly Diagnosed Diffuse Large B Cell Lymphoma GA101, Rituximab, Doxorubicin - Diffuse Large B Cell Lymphoma CD20 Positive | Phase 3 | Terminated | The Lymphoma Academic Research Organisation | 671 | 2012-09-01 | 2018-03-07 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (14) · Leukemia (8) · Lymphoma (7) · Lymphoma, Large B-Cell, Diffuse (6) · Neuroblastoma (5) · Lung Neoplasms (4) · Carcinoma, Non-Small-Cell Lung (3) · Burkitt Lymphoma (2) · Lymphoma, Large-Cell, Anaplastic (2) · Neoplasm, Residual (2) · Adenocarcinoma of Lung (1) · Disease (1) · Hodgkin Disease (1) · Leukemia, Biphenotypic, Acute (1) · Lymphoma, T-Cell (1)
German Society for Pediatric Oncology and Hematology GPOH gGmbH (3) · Goethe University (3) · Johann Wolfgang Goethe University Hospital (3) · Children's Cancer Group, China (2) · European Organisation for Research and Treatment of Cancer - EORTC (2) · Gustave Roussy, Cancer Campus, Grand Paris (2) · Lymphoma Study Association (2) · Peking Union Medical College Hospital (2) · The First Affiliated Hospital with Nanjing Medical University (2) · University Hospital Muenster (2) · University Hospital Schleswig-Holstein (2) · Associazione Italiana Ematologia Oncologia Pediatrica (1) · Children's Hospital Medical Center, Cincinnati (1) · Dermatologic Cooperative Oncology Group (1) · European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma (1)
Germany (21) · China (13) · Switzerland (12) · Belgium (9) · France (9) · Austria (8) · Czechia (8) · Italy (7) · Israel (5) · Sweden (5) · United Kingdom (5) · Australia (4) · Netherlands (4) · Norway (4) · Spain (4)
Frank Berthold, MD (4) · Dieter Hoelzer, MD,PhD (3) · Birgit Burkhardt, Prof. Dr. Dr. (2) · Dieter Hoelzer, MD, PhD (2) · Alain Delmer, MD (1) · Alfred Reiter, MD (1) · Axel Hauschild, MD (1) · Bertrand Coiffier, MD (1) · Claudia Pasqualini, MD PhD (1) · Daobin Zhou (1) · Daobin Zhou, M.D (1) · David J. Stewart, MD, FRCPC (1) · Delphine Senecal (1) · Denise Williams, MD (1) · Frank Berthold, Prof. (1)
PMID 16421426, PMID 19144982, PMID 19433688, PMID 20154213, PMID 21719599, PMID 22442346, PMID 22493293, PMID 24344215, PMID 26888258, PMID 26913693, PMID 27465021, PMID 27561722, PMID 28751559, PMID 29148893, PMID 31601692, PMID 33152759, PMID 37021527, PMID 42477805, PMID 10627444, PMID 10882162, PMID 11464889, PMID 11807147, PMID 11904735, PMID 12101494, PMID 12165894, PMID 12880954, PMID 12932669, PMID 14736927, PMID 16129365, PMID 16157935, PMID 16826357, PMID 16957145, PMID 17003366, PMID 17400912, PMID 17602078, PMID 17761975, PMID 17785567, PMID 18005385, PMID 18239620, PMID 18780832, PMID 19546402, PMID 19933916, PMID 20108339, PMID 20407035, PMID 20944675, PMID 20978195, PMID 21224045, PMID 21474675, PMID 21482186, PMID 21940215
2017 (1), 2019 (1)