35 completed, 16 unknown, 5 active not recruiting, 4 terminated. 28 Phase 2, 26 Phase 3, 5 Not applicable, 4 Phase 1, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab Biospecimen Collection, Bleomycin Sulfate, Brentuximab Vedotin - Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8 | Phase 3 | Recruiting | National Cancer Institute (NCI) | 1875 | 2023-05-11 | 2026-11-05 |
| Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer Biopsy Procedure, Biospecimen Collection, Cisplatin - Renal Pelvis and Ureter Urothelial Carcinoma | Phase 2 / Phase 3 | Recruiting | National Cancer Institute (NCI) | 131 | 2021-11-12 | 2026-11-05 |
| A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma Biospecimen Collection, Magnetic Resonance Imaging, Quality-of-Life Assessment - Recurrent Low Grade Astrocytoma, Recurrent WHO Grade 2 Glioma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 300 | 2021-02-16 | 2026-07-02 |
| Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer Cisplatin, Doxorubicin, Methotrexate - Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8 | Phase 2 | Completed | University of Washington | 17 | 2020-11-24 | 2025-09-18 |
| Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma Biospecimen Collection, Brentuximab Vedotin, Computed Tomography - Ann Arbor Stage III Hodgkin Lymphoma, Ann Arbor Stage III Lymphocyte-Depleted Classic Hodgkin Lymphoma | Phase 3 | Active not recruiting | National Cancer Institute (NCI) | 994 | 2019-08-29 | 2026-10-22 |
| Durvalumab and Standard Chemotherapy Before Surgery in Treating Patients With Variant Histology Bladder Cancer Carboplatin, Cisplatin, Cystectomy - Bladder Adenocarcinoma, Bladder Mixed Adenocarcinoma | Phase 2 | Terminated | Stanford University | 7 | 2019-04-10 | 2023-09-11 |
| PET-Directed Therapy With Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Classical Hodgkin Lymphoma Computed Tomography, Dacarbazine, Doxorubicin Hydrochloride - Classical Hodgkin Lymphoma, Lymphocyte-Depleted Classical Hodgkin Lymphoma | Phase 2 | Unknown | Northwestern University | 30 | 2017-11-09 | 2023-06-02 |
| Outcome of Cisplatin and Vinblastine Versus Paclitaxel and Carboplatin as Sequential Chemotherapy Followed by Radiotherapy in Locally Advanced Non-small Cell Lung Cancer Paclitaxel, Carboplatin, Cisplatin - Carcinoma, Non-Small-Cell Lung | Phase 4 | Completed | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh | 60 | 2017-01-01 | 2019-03-08 |
| Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer Methotrexate, Vinblastine, Doxorubicin - High Grade Upper Tract Urothelial Carcinoma | Phase 2 | Completed | ECOG-ACRIN Cancer Research Group | 36 | 2015-08-27 | 2023-07-10 |
| Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma Doxorubicin, Bleomycin, Vinblastine - Lymphoma | Phase 2 | Terminated | ECOG-ACRIN Cancer Research Group | 6 | 2013-05-24 | 2023-06-29 |
| Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma Brentuximab vedotin (SGN-35), Doxorubicin HCL, Vinblastine Sulfate - Hodgkin Lymphoma | Not applicable | Completed | Memorial Sloan Kettering Cancer Center | 118 | 2013-05-01 | 2026-06-04 |
| Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Combination With Cisplatin, Vinblastine, and Temozolomide in Treating Patients With Recurrent or Metastatic Melanoma Cisplatin, Gamma-Secretase Inhibitor RO4929097, Laboratory Biomarker Analysis - Recurrent Melanoma, Stage IV Skin Melanoma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 14 | 2010-08-01 | 2019-11-18 |
| Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma Bleomycin Sulfate, Doxorubicin Hydrochloride, Procarbazine Hydrochloride - Lymphoma | Phase 2 | Completed | Alliance for Clinical Trials in Oncology | 164 | 2010-05-01 | 2021-06-14 |
| Dose Dense MVAC for Muscle Invasive Bladder Cancer single arm dose dense MVAC - Muscle Invasive Bladder Cancer, High Risk Urothelial Carcinoma of the Upper Urinary Tracts | Phase 2 | Completed | Fox Chase Cancer Center | 54 | 2009-12-07 | 2019-09-17 |
| Surgery Alone or With CYC VBL and PRED or CVP Alone in Stage IA or IIA Nodular Lymphocyte-Predominant Hodgkin Lymphoma cyclophosphamide, prednisolone, vinblastine sulfate - Lymphoma | Phase 4 | Completed | Christine Mauz-Körholz | 225 | 2009-11-01 | 2023-12-13 |
| S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin Lymphoma bleomycin sulfate, filgrastim, ABVD regimen - Lymphoma, Nonneoplastic Condition | Phase 2 | Completed | SWOG Cancer Research Network | 371 | 2009-07-01 | 2022-08-18 |
| Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma bleomycin sulfate, filgrastim, pegfilgrastim - Lymphoma | Phase 3 | Completed | University College, London | 1202 | 2008-08-29 | 2024-05-08 |
| Neoadjuvant Chemotherapy With Methotrexate, Vinblastine, Adriamycin and Cisplatin (M-VAC) Plus Avastin in Patients With Urothelial Cancer Avastin, Cisplatin, Doxorubicin - Bladder Cancer | Phase 2 | Completed | M.D. Anderson Cancer Center | 60 | 2007-06-01 | 2016-03-31 |
| Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma carboplatin, vinblastine sulfate - Brain and Central Nervous System Tumors, Neurofibromatosis Type 1 | Phase 1 | Completed | Children's Oncology Group | 26 | 2006-06-01 | 2014-02-13 |
| Combination Chemotherapy in Treating Young Male Patients With Hodgkin's Lymphoma cyclophosphamide, doxorubicin hydrochloride, etoposide - Lymphoma | Phase 2 | Completed | Christine Mauz-Körholz | 16 | 2005-06-01 | 2020-03-26 |
Showing 20 of 62. Sign in to see all of them.
Lymphoma (24) · Hodgkin Disease (23) · Carcinoma, Non-Small-Cell Lung (9) · Lung Neoplasms (8) · Urinary Bladder Neoplasms (7) · Lymphoma, Large-Cell, Anaplastic (3) · Recurrence (3) · HIV Infections (2) · Testicular Neoplasms (2) · Urethral Neoplasms (2) · AIDS-Related Complex (1) · Acquired Immunodeficiency Syndrome (1) · Adenocarcinoma of Lung (1) · Astrocytoma (1) · Carcinoma (1)
European Organisation for Research and Treatment of Cancer - EORTC (8) · National Cancer Institute (NCI) (6) · Children's Oncology Group (5) · Children's Cancer and Leukaemia Group (4) · Stanford University (3) · Christine Mauz-Körholz (2) · ECOG-ACRIN Cancer Research Group (2) · Eastern Cooperative Oncology Group (2) · Gustave Roussy, Cancer Campus, Grand Paris (2) · M.D. Anderson Cancer Center (2) · Medical Research Council (2) · Memorial Sloan Kettering Cancer Center (2) · Alliance for Clinical Trials in Oncology (1) · American College of Radiology Imaging Network (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1)
United States (33) · United Kingdom (17) · Canada (13) · Italy (9) · France (8) · Germany (8) · Australia (7) · Belgium (7) · Netherlands (6) · Poland (6) · Switzerland (6) · Austria (5) · Puerto Rico (5) · Spain (5) · Sweden (5)
Sandra J. Horning, MD (3) · Christophe Ferme (2) · Dieter Koerholz, MD (2) · H. Eghbali, MD (2) · Ian E. Smith, MD (2) · John Martin, MD (2) · A. Barratt, MD (1) · Adrian Hodson (1) · Alex F Herrera (1) · Alfred Reiter, MD (1) · Anas Younes, MD (1) · Anita Kumar, MD (1) · Ann Barrett (1) · Anna Sureda (1) · Arif Hussain, MD (1)
PMID 40135712, PMID 37505794, PMID 14736927, PMID 15936157, PMID 16157935, PMID 16314615, PMID 16957145, PMID 17097834, PMID 17290057, PMID 17544497, PMID 17602078, PMID 17989384, PMID 19786668, PMID 19828373, PMID 19933916, PMID 20679620, PMID 20978195, PMID 21079154, PMID 21224045, PMID 21280197, PMID 21444917, PMID 21764821, PMID 22162575, PMID 22371887, PMID 23065953, PMID 23182987, PMID 23356491, PMID 23386127, PMID 23589673, PMID 24821881, PMID 25156886, PMID 25498218, PMID 25897153, PMID 26343003, PMID 27114593, PMID 27332902, PMID 27458003, PMID 28601705, PMID 29229324, PMID 30049811, PMID 30220622, PMID 30723079, PMID 31331918, PMID 31702432, PMID 32730187, PMID 32992341, PMID 33909449, PMID 36083129, PMID 37883739, PMID 38945791
U10CA180820 (2), U10CA180886 (2), 2004 (1), 2005 (1), N01CM62206 (1), N02CM62212 (1), P30CA008748 (1), P30CA060553 (1), U01CA069856 (1), U01CA079778 (1), U01CA080098 (1), U10CA021115 (1), U10CA032102 (1), U10CA180821 (1), U10CA180888 (1)