6 completed, 2 terminated, 1 suspended. 5 Phase 2, 4 Phase 1.
By phase and status
Follow vesatolimod: new trials by email Literature Review of vesatolimod trials Research Report on vesatolimod
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix .
Trial Phase Status Sponsor Enrollment Start Updated
Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1 ChAdOx1.tHIVconsv1, ChAdOx1.HIVconsv62, MVA.tHIVconsv3 - HIV-1-infection Phase 1 / Phase 2 Suspended 36 2024-04-01 2026-09-02 Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels Vesatolimod, Cobicistat, Voriconazole - Human Immunodeficiency Virus Type 1 (HIV-1) Infection Phase 1 Terminated 18 2022-08-19 2024-12-03 Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected Women Vesatolimod, VRC07523LS, CAP256V2LS - HIV-1-infection Phase 2 Completed 20 2022-06-09 2026-01-16 Safety, Tolerability and Immunogenicity of MVA.HTI and ChAdOx1.HTI With Vesatolimod in HIV-1 Positive Patients ChAdOx1.HTI, MVA.HTI, GS-9620 - HIV/AIDS Phase 2 Completed 50 2020-02-20 2023-07-27 Study to Evaluate the Safety and Efficacy of Vesatolimod in Antiretroviral Treated Human Immunodeficiency Virus (HIV-1) Infected Controllers Vesatolimod, Placebo, ART - HIV-1 Infection Phase 1 Completed 25 2017-05-09 2021-04-21 Study to Evaluate the Safety, Tolerability, and Efficacy of Vesatolimod in Combination With Tenofovir Disoproxil Fumarate (TDF) in Adults With Chronic Hepatitis B (CHB) Infection Who Are Currently Not Being Treated TDF, Vesatolimod, Placebo - Chronic Hepatitis B Phase 2 Completed 192 2015-11-10 2020-05-18 Safety and Biological Activity of Vesatolimod in HIV-1 Infected, Virologically Suppressed Adults Vesatolimod, Placebo, ARV regimen - HIV-1 Infection Phase 1 Completed 48 2015-01-29 2020-02-21 Long Term Follow-up Registry of Individuals Treated in A Gilead-Sponsored Trial in Individuals With Chronic Hepatitis B Infection GS-4774, GS-9620, Tenofovir disoproxil fumarate (TDF) - Chronic Hepatitis B Terminated 241 2014-12-09 2017-10-03 Study To Evaluate Safety and Efficacy of Vesatolimod for the Treatment of Chronic Hepatitis B Virus in Virally-Suppressed Participants Vesatolimod, Placebo - Chronic Hepatitis B Phase 2 Completed 162 2014-06-30 2020-10-14
Conditions studied Hepatitis B, Chronic (3) · Acquired Immunodeficiency Syndrome (2) · HIV Infections (1) · Hepatitis (1) · Hepatitis B (1) · Infections (1) · Liver Diseases (1)
Sponsors Gilead Sciences (7) · Aelix Therapeutics (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
Countries United States (7) · Canada (3) · Italy (3) · New Zealand (3) · South Korea (3) · Hong Kong (2) · Australia (1) · Brazil (1) · India (1) · Netherlands (1) · South Africa (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
Top investigators Jose R Arribas Lopez, Md, PhD (1) · Sharon Riddler, MD, MPH (1)
Results publications PMID 29104121 , PMID 29378197 , PMID 29851204 , PMID 33043969 , PMID 38979421 , PMID 40952649 , PMID 41449969 , PMID 41685863
NIH funding 2015 (2) , 2014 (1)