3 completed, 2 terminated, 1 unknown. 3 Phase 2, 2 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Total nodal irradiation: new trials by email Literature Review of Total nodal irradiation trials Research Report on Total nodal irradiation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma Fludarabine Phosphate, Mesna, Cyclophosphamide - Lymphoma | Not applicable | Completed | University of Wisconsin, Madison | 11 | 2016-03-10 | 2022-01-05 |
| CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma Anti-Thymocyte Globulin, Cyclosporine, Mycophenolate Mofetil - Acute Myeloid Leukemia, B-Cell Non-Hodgkin Lymphoma | Phase 2 | Completed | Robert Lowsky | 18 | 2015-06-01 | 2021-06-24 |
| Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell Transplant total nodal irradiation, laboratory biomarker analysis, questionnaire administration - Graft Versus Host Disease | Not applicable | Terminated | Wake Forest University Health Sciences | 4 | 2014-07-01 | 2018-11-23 |
| Zevalin Before Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma rituximab, ibritumomab tiuxetan, anti-thymocyte globulin - Refractory Non Hodgkin Lymphoma, Relapsed Non Hodgkin Lymphoma | Phase 2 | Unknown | Joseph Tuscano | 20 | 2013-03-12 | 2022-11-30 |
| Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment fludarabine phosphate, melphalan, nonmyeloablative allogeneic hematopoietic stem cell transplantation - Chronic Myeloproliferative Disorders, Leukemia | Phase 1 | Terminated | City of Hope Medical Center | 6 | 2008-11-01 | 2015-06-08 |
| Study to Evaluate the Efficacy of Rituximab in Combination With Low-dose Radiotherapy in Patients With Relapsed Non-Hodgkin's Lymphoma Rituximab, Total nodal irradiation - Non-Hodgkin's Lymphoma | Phase 2 | Completed | University of Cologne | 30 | 2004-06-01 | 2010-01-27 |
Lymphoma (3) · Lymphoma, Non-Hodgkin (3) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myeloid, Acute (2) · Myelodysplastic Syndromes (2) · Myeloproliferative Disorders (2) · Burkitt Lymphoma (1) · Congenital Abnormalities (1) · Graft vs Host Disease (1) · Hodgkin Disease (1) · Immunoblastic Lymphadenopathy (1) · Intraocular Lymphoma (1) · Leukemia (1) · Lymphoma, B-Cell (1) · Lymphoma, B-Cell, Marginal Zone (1)
City of Hope Medical Center (1) · Joseph Tuscano (1) · Robert Lowsky (1) · University of Cologne (1) · University of Wisconsin, Madison (1) · Wake Forest University Health Sciences (1)
United States (5) · Germany (1)
Andreas Engert (1) · Gordon Phillips (1) · Joseph Rosenthal, MD (1) · Joseph Tuscano (1) · Robert Lowsky (1) · Vaishalee P Kenkre (1)
P01CA049605 (1), P30CA012197 (1), P30CA033572 (1)