3 completed, 1 recruiting, 1 withdrawn. 5 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Recruiting 1, Withdrawn 1 |
| Phase 1 | 1 | Completed 1 |
Follow tizanidine: new trials by email Literature Review of tizanidine trials Research Report on tizanidine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study Tizanidine, Standard-of-Care Therapy - Post Operative, Post Operative Analgesia | Phase 2 | Recruiting | Hartford Hospital | 186 | 2026-08-21 | 2026-09-21 |
| Gabapentin and Tizanidine for Insomnia in Chronic Pain Gabapentin, Placebo, Tizanidine - Insomnia Due to Medical Condition, Chronic Pain | Phase 2 | Completed | University of California, San Diego | 9 | 2020-07-29 | 2025-01-03 |
| Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back Pain SPARC1401-low dose, SPARC1401-mid dose, SPARC1401-high dose - Acute Muscle Pain | Phase 2 | Withdrawn | Sun Pharma Advanced Research Company Limited | 2016-11-01 | 2019-05-03 | |
| A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial Tizanidine, Placebo, Moxifloxacin - Spasticity | Phase 2 | Completed | Acorda Therapeutics | 136 | 2013-04-01 | 2021-03-23 |
| Study of Nighttime Dosing of Sublingual Tizanidine (12 mg) in Multiple Sclerosis (MS) Patients With Significant Spasticity Tizanidine (sublingual or oral) - Muscle Spasticity | Phase 1 / Phase 2 | Completed | Teva GTC | 20 | 2006-12-01 | 2009-01-21 |
Muscle Spasticity (2) · Chronic Pain (1) · Multiple Sclerosis (1) · Sleep Initiation and Maintenance Disorders (1)
Acorda Therapeutics (1) · Hartford Hospital (1) · Sun Pharma Advanced Research Company Limited (1) · Teva GTC (1) · University of California, San Diego (1)
United States (3) · Israel (1)
Arnon Karni, MD (1) · Elena Tunitsky, MD (1) · Mathews Adera, MD (1) · Nathaniel Schuster, MD (1) · Sindhura Vallabhaneni, MD (1)
PMID 11130605, PMID 12269398, PMID 16038812, PMID 20223444, PMID 26555871, PMID 27521884, PMID 38529017, PMID 41687037, PMID 41854462, PMID 8080219, PMID 8646957
UL1TR000100 (1)