3 completed. 3 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 1 | Completed 1 |
Follow tinostamustine: new trials by email Literature Review of tinostamustine trials Research Report on tinostamustine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma Radiation Therapy, Tinostamustine - Glioblastoma, Gliosarcoma | Phase 1 | Completed | M.D. Anderson Cancer Center | 5 | 2018-08-13 | 2025-06-04 |
| Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors. Tinostamustine 60mg/m2 over 30min, Tinostamustine 80mg/m2 over 30min, Tinostamustine 100mg/m2 over 30min - Small Cell Lung Cancer, Soft Tissue Sarcoma | Phase 1 / Phase 2 | Completed | Mundipharma Research Limited | 71 | 2017-11-08 | 2024-10-21 |
| Study of Tinostamustine, First-in-Class Alkylating HDACi Fusion Molecule, in Relapsed/Refractory Hematologic Malignancies Tinostamustine - Hematological Malignancies, Multiple Myeloma | Phase 1 | Completed | Mundipharma Research Limited | 106 | 2016-04-14 | 2024-07-25 |
Breast Neoplasms (1) · Endometrial Neoplasms (1) · Fallopian Tube Neoplasms (1) · Gastrointestinal Stromal Tumors (1) · Glioblastoma (1) · Gliosarcoma (1) · Hematologic Neoplasms (1) · Hodgkin Disease (1) · Lymphoma, T-Cell, Cutaneous (1) · Multiple Myeloma (1) · Neoplasm Metastasis (1) · Ovarian Neoplasms (1) · Recurrence (1) · Sarcoma (1) · Small Cell Lung Carcinoma (1)
Mundipharma Research Limited (2) · M.D. Anderson Cancer Center (1)
United States (3) · Italy (2) · Netherlands (2) · Spain (2) · Canada (1) · France (1) · Germany (1) · Switzerland (1)
Ana Oaknin, MD (1) · Pier L Zinzani, MD,PhD (1) · Shiao-Pei S Weathers (1) · Shivaani Kummar, MD (1)