13 completed, 4 recruiting, 4 unknown, 1 not yet recruiting. 10 Phase 2, 6 Phase 4, 4 Not applicable, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 5, Recruiting 3, Not yet recruiting 1, Unknown 1 |
| Phase 4 | 6 | Completed 6 |
| Not applicable | 4 | Unknown 3, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Teniposide: new trials by email Literature Review of Teniposide trials Research Report on Teniposide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL Teniposide, Orelabrutinib, MTX - Primary Central Nervous System Lymphoma | Phase 2 / Phase 3 | Recruiting | Huashan Hospital | 215 | 2025-10-01 | 2026-08-19 |
| Combination Regimen of Teniposide, PD-1 Monoclonal Antibody and Selinixor for Patients With Relapsed or Refractory PCNSL Induction therapy-2 cycles of VPX (Teniposide, PD-1 monoclonal antibody plus Selinixor), Consolidation therapy with ASCT after TB (Thiotepa plus Busulfan) preconditioning, Consolidation therapy-4 cycles of VPX (Teniposide, PD-1 monoclonal antibody plus Selinixor) - Primary Central Nervous System Lymphoma (PCNSL) | Not applicable | Recruiting | The First Affiliated Hospital of Soochow University | 40 | 2025-01-02 | 2025-07-20 |
| Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS Albumin-Bound Paclitaxel, Epirubicin, Gemcitabine - Rare Tumour | Phase 2 | Not yet recruiting | Peking University Shenzhen Hospital | 200 | 2025-01-01 | 2024-11-18 |
| Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin. Teniposide Injection - GCT, Germ Cell Tumor | Phase 2 | Recruiting | Chengcheng Guo | 40 | 2024-08-13 | 2025-09-23 |
| Teniposide, Cisplatin and Serplulimab for Treatment of ES-SCLC, a Randomized Controlled Study Teniposide, Etoposide, serplulimab - Small-cell Lung Cancer | Phase 2 | Recruiting | Sun Yat-sen University | 90 | 2024-02-01 | 2026-05-13 |
| Teniposide Incorporating Bu/Cy Conditioning Regimen for HLH With Central Nervous System Involvemen Teniposide - HLH | Not applicable | Unknown | Beijing Friendship Hospital | 20 | 2023-10-22 | 2023-11-02 |
| Online Group Therapy for Breast Cancer Online Group Therapy for PTG, Online Support Group - Breast Cancer | Not applicable | Unknown | Dokuz Eylul University | 51 | 2022-01-15 | 2022-02-28 |
| Influence of the Operative Day on the Average Duration of Stay in Primary Hip and Knee Replacements Determine the DMS of the Total Hip Prosthesis of the University Hospital of Amiens (PTH) and the Total Knee Prosthesis (PTG) - Length of Stay, Arthroplasty | Completed | Centre Hospitalier Universitaire, Amiens | 1663 | 2018-09-01 | 2023-05-17 | |
| Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma dexamethasone, vincristine sulfate, rituximab - Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood B-Lymphoblastic Lymphoma | Phase 2 | Completed | St. Jude Children's Research Hospital | 80 | 2013-04-15 | 2022-09-28 |
| Intensified Post Remission Therapy Containing PEG-Asparaginase Daunorubicin, Vincristine, Prednisone, Methotrexate, PEG-Asparaginase, 6-Mercaptopurine, Cytoxan, Cytosine Arabinoside, VM-26 and 6-Thioguanine - Acute Lymphoblastic Leukemia | Phase 2 | Completed | University of Southern California | 47 | 2004-07-01 | 2014-05-22 |
| Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab Cyclophosphamide, Dexamethasone / Prednisolone, Vincristine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Johann Wolfgang Goethe University Hospital | 60 | 2004-04-01 | 2010-08-23 |
| Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia Etoposide, cytarabine, vincristine, dexamethasone, methotrexate, teniposide, PEG-asparaginase, mitoxantrone, cyclophosphamide, mercaptopurine, vinblastine - Acute Lymphoblastic Leukemia, Lymphoma, Lymphoblastic | Phase 2 | Completed | St. Jude Children's Research Hospital | 47 | 2003-11-01 | 2017-07-28 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) Cyclophosphamide, Dexamethasone, Vincristine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 1883 | 2003-04-01 | 2022-08-18 |
| Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia asparaginase, cyclophosphamide, cytarabine - Leukemia | Not applicable | Unknown | Universitätsklinikum Hamburg-Eppendorf | 550 | 2003-01-01 | 2013-08-26 |
| Treatment of High Risk Adult Acute Lymphoblastic Leukemia Vincristine, Daunorubicin, Prednisone - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 100 | 2003-01-01 | 2020-04-07 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) Dexamethasone / Prednisolone, Cyclophosphamide, Methotrexate - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 225 | 1999-10-01 | 2023-03-20 |
| Combination Chemotherapy, Bone Marrow or Peripheral Stem Cell Transplantation, and/or Biological Therapy in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma aldesleukin, filgrastim, recombinant interferon alfa - Lymphoma | Phase 2 | Completed | Northwestern University | 1999-10-01 | 2012-06-06 | |
| Ifosfamide, Teniposide, and Paclitaxel in Treating Patients With Relapsed Non-Hodgkin's Lymphoma ifosfamide, paclitaxel, teniposide - Lymphoma | Phase 1 / Phase 2 | Completed | Northwestern University | 1999-02-01 | 2012-06-06 | |
| A Study of Children With Refractory or Relapsed ALL Topotecan, dexamethasone, vincristine, E. coli Asparaginase, PEG-L-asparaginase, erwinia asparaginase - Acute Lymphoblastic Leukemia | Phase 3 | Completed | St. Jude Children's Research Hospital | 40 | 1997-02-01 | 2008-06-04 |
| Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia Adriamycin, Cyclophosphamide, Cytarabine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 40 | 1997-02-01 | 2023-03-20 |
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Precursor Cell Lymphoblastic Leukemia-Lymphoma (10) · Leukemia (5) · Lymphoma (4) · Neoplasm, Residual (2) · Breast Neoplasms (1) · Burkitt Lymphoma (1) · Lymphoma, Follicular (1) · Lymphoma, Large B-Cell, Diffuse (1) · Lymphoma, Large-Cell, Immunoblastic (1) · Lymphoma, Mantle-Cell (1) · Lymphoma, Non-Hodgkin (1) · Neoplasms, Germ Cell and Embryonal (1) · Small Cell Lung Carcinoma (1)
Goethe University (4) · St. Jude Children's Research Hospital (3) · Johann Wolfgang Goethe University Hospital (2) · Northwestern University (2) · Beijing Friendship Hospital (1) · Centre Hospitalier Universitaire, Amiens (1) · Chengcheng Guo (1) · Dokuz Eylul University (1) · Huashan Hospital (1) · PETHEMA Foundation (1) · Peking University Shenzhen Hospital (1) · Sun Yat-sen University (1) · The First Affiliated Hospital of Soochow University (1) · University of Southern California (1) · Universitätsklinikum Hamburg-Eppendorf (1)
Germany (7) · United States (6) · China (5) · France (1) · Spain (1) · Turkey (Türkiye) (1)
Dieter Hoelzer, MD,PhD (3) · Sima Jeha, MD (3) · Dieter Hoelzer, MD, PhD (2) · Leo I. Gordon, MD (2) · Dan Douer, MD (1) · Dieter Hoelzer, MD (1) · Gritta Janka-Schaub (1) · Tong Chen (1) · Wenfeng Fang (1) · Zhao Wang (1)
PMID 19144982, PMID 22442346, PMID 22493293, PMID 27561722, PMID 28751559, PMID 18162124, PMID 23024237, PMID 24516026, PMID 24752047, PMID 34132444, PMID 35834762, PMID 42477805