10 recruiting, 7 completed, 6 not yet recruiting, 5 unknown. 14 Phase 2, 5 Not applicable, 4 Phase 1.
Follow Targeted therapy: new trials by email Literature Review of Targeted therapy trials Research Report on Targeted therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shuganhuazhuo Formula for Advanced Hepatocellular Carcinoma With Damp-Heat Syndrome Shuganhuazhuo Formula, Targeted therapy, Immunotherapy - HCC - Hepatocellular Carcinoma, Chinese Herbal Medicine | Phase 2 | Not yet recruiting | Xiang-Qian | 120 | 2027-09-01 | 2026-08-27 |
| Testing Repeat Radiation Therapy for Recurrent Non-small Cell Lung Cancer Biospecimen Collection, Computed Tomography, Immunotherapy - Locally Recurrent Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8 | Phase 2 | Not yet recruiting | NRG Oncology | 138 | 2026-12-18 | 2026-09-23 |
| Lenalidomide Plus Targeted Therapy and Immunotherapy for Refractory HCC Lenalidomide, Targeted Therapy, Immune Checkpoint Inhibitors - Hepatocellular Carcinoma (HCC) | Phase 2 | Recruiting | Shunda Du | 32 | 2026-08-12 | 2026-09-21 |
| TACE Combined With Thermal Ablation and ADC, PD-1, and Chemotherapy as First-line Treatment for HER2-highly-expressing Gastric Cancer With Liver Metastases: A Multicenter, Single-arm Prospective Clinical Study. TACE combined with thermal ablation, Targeted Therapy, Immunotherapy - Gastric Cancer With Liver Metastases | Phase 2 | Not yet recruiting | Shandong Provincial Hospital | 40 | 2026-08-01 | 2026-05-22 |
| A Prospective Study of Response-adapted Low-dose Radiotherapy Combined With Orelabrutinib for Localized Mucosa-associated Lymphoid Tissue Extranodal Marginal Zone Lymphoma Radiation (Very low dose), Radiation (Standard) - Lymphoma of the Mucosa Associated Lymphoid Tissue (MALT) | Phase 2 | Not yet recruiting | Ruijin Hospital | 140 | 2026-08-01 | 2026-07-15 |
| Sequential FOLFOX-HAIC-TACE Plus Sintilimab-Bevacizumab Neoadjuvant Therapy Versus Direct Resection in Resectable High-Risk Recurrence Hepatocellular Carcinoma FOLFOX regimen, Immunotherapy, targeted therapy - Hepatocellular Carcinoma | Phase 1 / Phase 2 | Not yet recruiting | BinYong Liang | 100 | 2026-04-30 | 2026-04-13 |
| A Study on the Heterogeneity of Efficacy of Interventional Therapy Combined With Systemic Therapy for Liver Cancer Based on Multi-center Real-world Data Interventional therapy, Systemic therapy - Hepatocellular Carcinoma (HCC) | Not yet recruiting | Xuhua Duan | 2000 | 2025-10-01 | 2025-09-05 | |
| A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects Fecal microbiota transplantation (FMT) - Fecal Microbiota Transplantation (FMT), Gastrointestinal Neoplasms | Phase 1 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 90 | 2025-09-01 | 2026-01-06 |
| A Clinical Trial of Neoadjuvant Targeted Therapy, Immunotherapy, and Lysogenic HSV-Based Virotherapy in Resectable Head and Neck Squamous Cell Carcinoma Tislelizumab, Afatinib, Lysogenic HSV virus. - HNSCC, Lysogenic HSV Virus | Phase 1 / Phase 2 | Active not recruiting | West China Hospital | 29 | 2025-06-10 | 2026-07-01 |
| Phase II Study of Serplulimab Combined with First-Line Targeted Therapy, Chemotherapy, and Radiation in Advanced Colorectal Cancer Serplulimab, Chemotherapy, SABR - Advanced Colorectal Carcinoma, Immunotherapy | Phase 2 | Recruiting | Fudan University | 208 | 2025-03-01 | 2025-03-14 |
| Clinical Study of Carbon Ion Radiotherapy for Pancreatic Cancer. carbon ion radiotherapy (CIRT) - Pancreatic Cancer Metastatic, Pancreatic Cancer Non-resectable | Not applicable | Recruiting | Gansu Wuwei Tumor Hospital | 62 | 2025-03-01 | 2025-03-25 |
| Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC Tislelizumab, Afatinib, Low dose radiotherapy - Head and Neck Cancer | Phase 2 | Withdrawn | West China Hospital | 2025-01-20 | 2025-11-19 | |
| A Clinical Study on Neoadjuvant Treatment of Resectable Head and Neck Squamous Carcinoma With Immune-targeted Therapy and Lysogenic HSV Virus Lysogenic HSV virus., Tislelizumab, Afatinib - HNSCC, Lysogenic HSV Virus | Phase 1 | Withdrawn | West China Hospital | 2024-12-15 | 2026-10-16 | |
| Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy - Non-small Cell Lung Cancer, Older People | Phase 2 | Recruiting | Jian Chen | 29 | 2024-08-08 | 2025-06-13 |
| Local Liver Treatment for Multi-organ Colorectal Cancer Metastases Radical local Surgery, Systemic therapy, Interventional therapy - Metastatic Colorectal Carcinoma, Multi-organ Metastatic Colorectal Cancer | Not applicable | Recruiting | Anhui Provincial Hospital | 130 | 2024-07-01 | 2024-06-10 |
| Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer Immunotherapy, Targeted therapy, Hyperthermia - Metastatic Castration-resistant Prostate Cancer (CRPC) | Phase 2 | Recruiting | Pengyuan Liu | 60 | 2024-01-01 | 2024-02-08 |
| Determining Individualized Cancer Therapy in Pancreatic Cancer Targeted Therapy - Pancreatic Neoplasms | Recruiting | Medical College of Wisconsin | 1000 | 2023-12-04 | 2026-05-05 | |
| Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma camrelizumab and apatinib - Chordoma, Chemotherapy Effect | Phase 2 | Unknown | Xuanwu Hospital, Beijing | 30 | 2023-10-30 | 2023-11-20 |
| Young Patients With Early Breast Cancer operation - Breast Cancer Female | Active not recruiting | Peking Union Medical College Hospital | 1000 | 2023-08-01 | 2025-08-03 | |
| Prospective Research for Elderly (≥65 Years Old) Early Breast Cancer Patients operation, Bisphosphonate - Breast Cancer Female | Unknown | Peking Union Medical College Hospital | 1000 | 2022-04-01 | 2023-01-11 |
Showing 20 of 34. Sign in to see all of them.
Carcinoma, Hepatocellular (5) · Carcinoma, Non-Small-Cell Lung (3) · Lung Neoplasms (3) · Neoplasms (3) · Pancreatic Neoplasms (3) · Breast Neoplasms (2) · Cholangiocarcinoma (2) · Colorectal Neoplasms (2) · Head and Neck Neoplasms (2) · Melanoma (2) · Squamous Cell Carcinoma of Head and Neck (2) · Thymus Neoplasms (2) · Adenocarcinoma (1) · Adrenal Gland Neoplasms (1) · Anus Neoplasms (1)
West China Hospital (3) · Fox Chase Cancer Center (2) · Peking Union Medical College Hospital (2) · Shanghai Chest Hospital (2) · Anhui Provincial Hospital (1) · BinYong Liang (1) · Fudan University (1) · Gansu Wuwei Tumor Hospital (1) · Jian Chen (1) · Medical College of Wisconsin (1) · NRG Oncology (1) · Pengyuan Liu (1) · Ruijin Hospital (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Shandong Provincial Hospital (1)
China (20) · United States (5) · Belgium (1) · Germany (1) · United Kingdom (1)
Xingchen Peng (2) · Yunfei Yuan (2) · Angela Alistar (1) · Anthony Olszanski (1) · Els Wauters, MD, PhD (1) · Hossein Borghaei (1) · Jennifer Johnson, MD, PhD (1) · Ji-Zhou Wang, MD PhD (1) · Jingfang Mao, PHD (1) · Li Bing, PhD. (1) · Mandana Kamgar, MD (1) · Michael Koller, PhD (1) · Nitin Ohri (1) · Paul Lorigan, MBBCH, FRCP (1) · Qing-Song Yang, MD (1)
PMID 20921468, PMID 22397650, PMID 22966018, PMID 23127803, PMID 24071851, PMID 25109877, PMID 25326492, PMID 26342236, PMID 26873727, PMID 27853199, PMID 29149611, PMID 32213338, PMID 32853681, PMID 34393512, PMID 34665942, PMID 37429302, PMID 38051328, PMID 39822559
P30CA006927 (2), P30CA012197 (1), U10CA180868 (1)