8 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 6 Phase 2, 3 Phase 3, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Active not recruiting 1, Terminated 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Streptozocin: new trials by email Literature Review of Streptozocin trials Research Report on Streptozocin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Sitagliptin, Pioglitazone and Dapagliflozine on Myocardial Infarction in Diabetic Rats standard normal diet, low dose Streptozotocin, Sitagliptin (Novartis, USA) - Diabetic, Myocardial Infarction | Phase 4 | Completed | Al-Azhar University | 50 | 2024-10-30 | 2025-08-14 |
| Reduce Incidence of Pre-Dialysis Hyperkalaemia With Sodium Zirconium Cyclosilicate in Chinese Subjects Sodium Zirconium Cyclosilicate, Placebo - Hyperkalemia | Phase 3 | Completed | AstraZeneca | 134 | 2020-11-16 | 2023-03-28 |
| An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia Sodium Zirconium Cyclosilicate (SZC) Reduced Dose Level, Sodium Zirconium Cyclosilicate (SZC) Dose Level 1 (DL1), Sodium Zirconium Cyclosilicate (SZC) Dose Level 2 (DL2) - Hyperkalaemia | Phase 3 | Recruiting | AstraZeneca | 140 | 2019-04-02 | 2026-08-13 |
| Two Chemotherapy Regimens Plus or Minus Bevacizumab LV5FU2, Streptozocin, Capecitabine - Pancreatic Cancer | Phase 2 | Active not recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 140 | 2018-06-26 | 2024-05-08 |
| Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors Avastin, Fluorouracil, Doxorubicin - Pancreatic Cancer | Phase 2 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 1 | 2007-08-01 | 2017-03-23 |
| A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Endocrine Tumors of the Gastrointestinal Tract. bevacizumab [Avastin], 5 FU, Streptozotocin - Neoplasms | Phase 2 | Completed | Hoffmann-La Roche | 83 | 2007-07-01 | 2015-01-22 |
| Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors capecitabine, cisplatin, streptozocin - Gastrointestinal Carcinoid Tumor, Islet Cell Tumor | Phase 2 | Completed | Cambridge University Hospitals NHS Foundation Trust | 84 | 2005-08-01 | 2013-08-07 |
| Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT) Etoposide, Doxorubicin, Cisplatin - Carcinoma, Adrenal Cortical | Phase 3 | Completed | Collaborative Group for Adrenocortical Carcinoma Treatment | 304 | 2004-06-01 | 2016-09-21 |
| Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer monoclonal antibody A33, carmustine, fluorouracil - Colorectal Cancer | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 18 | 1998-06-01 | 2013-06-27 |
| Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms carmustine, mercaptopurine, streptozocin - Anaplastic Astrocytoma, Anaplastic Oligodendroglioma | Phase 2 | Completed | Emory University | 35 | 1996-08-01 | 2015-03-25 |
| Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas combined chemotherapy with streptozotocin, 5-fluorouracil, and doxorubicin - Islet Cell Adenoma, Neoplasm Metastasis | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 999 | 1978-09-01 | 2008-03-04 |
Adenoma, Islet Cell (2) · Gastrinoma (2) · Hyperkalemia (2) · Neoplasm Metastasis (2) · Neoplasms (2) · Pancreatic Neoplasms (2) · Adrenocortical Carcinoma (1) · Astrocytoma (1) · Brain Neoplasms (1) · Carcinoma, Islet Cell (1) · Colonic Neoplasms (1) · Colorectal Neoplasms (1) · Genetic Diseases, Inborn (1) · Glioblastoma (1) · Glioma (1)
AstraZeneca (2) · Al-Azhar University (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Collaborative Group for Adrenocortical Carcinoma Treatment (1) · Emory University (1) · Gustave Roussy, Cancer Campus, Grand Paris (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Hoffmann-La Roche (1) · Memorial Sloan Kettering Cancer Center (1) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (1)
United States (5) · France (3) · China (2) · Germany (2) · United Kingdom (2) · Australia (1) · Austria (1) · Brazil (1) · Canada (1) · Egypt (1) · India (1) · Italy (1) · Japan (1) · Netherlands (1) · Poland (1)
Britt Skogseid, MD (1) · Jonathan Strosberg, M.D. (1) · Larry Kvols, M.D. (1) · Mark R. Gilbert (1) · Martin Fassnacht, MD (1) · Pippa Corrie, PhD, FRCP (1) · Sydney Welt, MD (1) · Tim Meyer, MD, BSc, MRCP, PhD (1) · Zhaohui Ni (1)
PMID 22551107, PMID 32588430, PMID 37385905
2017 (1), 2018 (1), 2023 (1)