2 completed, 1 not yet recruiting, 1 recruiting. 2 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
Follow Standard TB treatment: new trials by email Literature Review of Standard TB treatment trials Research Report on Standard TB treatment
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery Metformin, N-Acetylcysteine (NAC) Treatment, Standard TB treatment - Tuberculosis | Phase 3 | Not yet recruiting | Open Source Pharma Foundation | 1104 | 2026-01-01 | 2025-08-22 |
| A Confirmatory Trial of Adjunctive NAC to Prevent Post Tuberculosis Lung Disease N-Acetyl Cysteine (NAC), Standard TB treatment - Tuberculosis (TB) | Not applicable | Recruiting | The Aurum Institute NPC | 242 | 2025-04-28 | 2025-04-30 |
| Optimization of the TB Treatment Regimen Cascade double rimfampicin, Standard TB treatment - Tuberculosis, Pulmonary | Phase 3 | Completed | Damien Foundation | 701 | 2014-11-01 | 2020-02-13 |
| Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings Didanosine, Efavirenz, Lamivudine - HIV Infections, Tuberculosis | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 592 | 2009-08-01 | 2010-03-29 |
Tuberculosis (3) · Directly Observed Therapy (1) · HIV Infections (1) · Recurrence (1) · Tuberculosis, Pulmonary (1)
Damien Foundation (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Open Source Pharma Foundation (1) · The Aurum Institute NPC (1)
Bangladesh (1) · South Africa (1) · The Gambia (1)
Andrea Rachow, MD (1) · Aung Kya Jai Maug, MD (1) · Robert Wallis, MD (1) · Salim S. Abdool Karim, MBChB, PhD (1)
PMID 22108776, PMID 34849651, PMID 38019456, PMID 38850838, PMID 39189858, PMID 39756697