7 completed, 4 unknown, 3 active not recruiting, 2 recruiting. 6 Phase 2, 5 Not applicable, 4 Phase 1, 4 Phase 3, 4 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase II Clinical Study of HRS-9563 in Patients With Mild to Moderate Hypertension HRS-9563 Injection, sodium chloride injection - Mild to Moderate Hypertension | Phase 2 | Active not recruiting | Fujian Shengdi Pharmaceutical Co., Ltd. | 238 | 2026-01-14 | 2026-07-31 |
| A Clinical Study Evaluating the Efficacy and Safety of HRS-7249 in Treating Patients With Hyperlipidemia HRS-7249 Injection, Sodium Chloride Injection - Hyperlipidemia | Phase 2 | Active not recruiting | Fujian Shengdi Pharmaceutical Co., Ltd. | 224 | 2025-08-12 | 2026-06-03 |
| Evaluation of the Benefit and Safety of Localized Tissue Hydration in the Management of Chronic Low Back Pain Sodium Chloride injection - Chronic Low-back Pain | Phase 2 | Completed | GCS Ramsay Santé pour l'Enseignement et la Recherche | 30 | 2025-02-28 | 2026-06-15 |
| A Safety and Tolerability Study of BPR-30221616 Injection in Healthy Subjects BPR-30221616 Injection, Sodium Chloride Injection - Healthy Participants | Phase 1 | Recruiting | Chengdu Brilliant Pharmaceutical Co., Ltd. | 48 | 2025-01-10 | 2025-02-12 |
| The Effect of Esketamine on Sleep Disturbance normal saline, Esketamine - Sleep Disturbance | Not applicable | Completed | Tianjin Medical University General Hospital | 204 | 2024-05-03 | 2025-02-12 |
| Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke Multiple Electrolyte, Normal Saline - Critical Care, Hyperchloremia | Phase 4 | Not yet recruiting | Capital Medical University | 342 | 2024-05-01 | 2024-04-19 |
| Phase I Clinical Trial of PCV24 in Children Aged 2 Months (Minimum 6 Weeks) to 17 Years PCV24 formulation 1, PCV24 formulation 2, 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine - Pneumococcal Infectious Disease | Phase 1 | Completed | Reinovax Biologics Co., LTD | 230 | 2024-04-27 | 2026-08-17 |
| Efficacy and Safety of Intravenous Meloxicam in Subjects With Moderate-to-severe Pain Following Abdominal Surgery Meloxicam Injection, Sodium Chloride Injection - Participants With Acute Moderate to Severe Pain Following Abdominal Surgery | Phase 3 | Completed | Yangtze River Pharmaceutical Group Co., Ltd. | 224 | 2024-01-29 | 2025-04-01 |
| Evaluate the Safety, Tolerability of BAT6026 Monoclonal antibody BAT6026, sodium chloride injection - Dermatitis, Atopic | Phase 1 / Phase 2 | Active not recruiting | Bio-Thera Solutions | 33 | 2023-11-09 | 2026-10-02 |
| Assessing the Effectiveness and Safety of Interferon Bladder Infusion for the Treatment of Interstitial Cystitis Interferon, Sodium Hyaluronate, Sodium Chloride Injection - Interstitial Cystitis | Phase 2 / Phase 3 | Unknown | West China Hospital | 129 | 2023-10-15 | 2023-09-15 |
| Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery Dexmedetomidine Injection, Ropivacaine and Dexmedetomidine, Sodium Chloride Injection - Dexmedetomidine, Fascia Iliaca Block | Phase 1 | Unknown | Qianfoshan Hospital | 207 | 2023-02-05 | 2024-09-26 |
| Proximal Lower Limb Intramuscular Block : Effects on Hemiparetic Gait Ropivacaine injection, Sodium Chloride Injection - Neurologic Disorder, Spastic Hemiplegia | Not applicable | Unknown | Henri Mondor University Hospital | 30 | 2022-09-09 | 2022-08-29 |
| A Study of Huperzine A Injection in Reducing Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery Sodium Chloride Injection, Huperzine A Injection - Injection, Non-cardiac Surgery | Not applicable | Recruiting | Second Affiliated Hospital of Wenzhou Medical University | 40 | 2022-06-10 | 2025-04-02 |
| Comparison of Two Analgesic Strategies After Scheduled Caesarean Rachianesthesia, Sodium Chloride Injection, Morphine - Analgesia | Phase 4 | Completed | GCS Ramsay Santé pour l'Enseignement et la Recherche | 104 | 2021-03-22 | 2024-08-05 |
| Controlling Rapid Atrial Fibrillation With Dexmedetomidine Dexmedetomidine Hydrochloride, Normal Saline - Rapid Atrial Fibrillation, Heart Rate Control | Phase 2 / Phase 3 | Terminated | Stony Brook University | 13 | 2019-08-21 | 2024-06-04 |
| Early Initiation of Low Dose Tirofiban for PPCI in STEMI Patients. Tirofiban, Normal saline - ST Elevation Myocardial Infarction | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 500 | 2019-05-14 | 2020-01-22 |
| Metabolic Phenotyping During Stress Hyperglycemia in Cardiac Surgery Patients Dulaglutide Injection, Saline Injection - Stress Hyperglycemia | Phase 4 | Terminated | Emory University | 28 | 2019-03-08 | 2024-05-30 |
| Regional Anesthesia in Hip Arthroscopy regional anesthesia bupivacaine, regional anesthesia placebo - Femoroacetabular Impingement | Not applicable | Withdrawn | University of Missouri-Columbia | 2015-10-01 | 2017-02-10 | |
| Recombinant Endostatin Combined With Vinorelbine and Cisplatin in Patients With Advanced Non-small Cell Lung Cancer Placebos, Sulijia - Advanced Non-small Cell Lung Cancer | Phase 3 | Completed | Jiangsu Wuzhong Pharmaceutical Group Co., Ltd. | 560 | 2011-11-10 | 2017-04-17 |
| A Study to Evaluate the Effect of Lipid Infusion on Toll Like Receptor 4 (TLR4) Signaling Intralipid 20%, Saline - Diabetes, Obesity | Not applicable | Completed | The University of Texas Health Science Center at San Antonio | 12 | 2008-01-01 | 2016-01-25 |
Emergence Delirium (2) · Obesity (2) · Agnosia (1) · Atrial Fibrillation (1) · Bites and Stings (1) · Carcinoma, Non-Small-Cell Lung (1) · Cystitis, Interstitial (1) · Dermatitis, Atopic (1) · Diabetes Mellitus (1) · Femoracetabular Impingement (1) · Gait Disorders, Neurologic (1) · Hemiplegia (1) · Hemorrhagic Stroke (1) · Hyperlipidemias (1) · Inflammation (1)
Fujian Shengdi Pharmaceutical Co., Ltd. (2) · GCS Ramsay Santé pour l'Enseignement et la Recherche (2) · Bio-Thera Solutions (1) · Capital Medical University (1) · Chengdu Brilliant Pharmaceutical Co., Ltd. (1) · Emory University (1) · Henri Mondor University Hospital (1) · Jiangsu Wuzhong Pharmaceutical Group Co., Ltd. (1) · Qianfoshan Hospital (1) · Reinovax Biologics Co., LTD (1) · Second Affiliated Hospital of Wenzhou Medical University (1) · Shanghai Zhongshan Hospital (1) · Stony Brook University (1) · The University of Texas Health Science Center at San Antonio (1) · Tianjin Medical University General Hospital (1)
China (12) · United States (4) · France (2)
Ajay Aggarwal, MD (1) · Andreas Kalogeropoulos, MD MPH PhD (1) · Francisco Pasquel, MD, MPH (1) · Guolin Wang, MD, PhD (1) · Jian-Xin Zhou, MD (1) · Juying Qian, MD (1) · Nicolas Musi, MD (1) · Ting Li, MD. PhD (1) · Wei-min Li (1) · Yuankai Shi, M.D. (1) · Yunong Zhang, Master (1)
PMID 24337154, PMID 38587846, PMID 39237149, PMID 40804260
K23GM128221 (1), R01DK080157 (1)