4 completed, 2 terminated, 1 withdrawn. 4 Phase 2, 3 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 1, Withdrawn 1 |
| Not applicable | 3 | Completed 2, Terminated 1 |
Follow Sodium Benzoate: new trials by email Literature Review of Sodium Benzoate trials Research Report on Sodium Benzoate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sodium Benzoate and/or N-Acetylcysteine Added to TAU in Patients With Early Schizophrenia Spectrum Disorder. Sodium Benzoate, N-Acetylcysteine, Placebo - Schizophrenia, Schizophreniform Disorders | Phase 2 | Completed | Pakistan Institute of Living and Learning | 64 | 2019-01-01 | 2022-04-27 |
| Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease. Sodium Benzoate, Powdered table sugar as palcebo - Chronic Liver Disease | Not applicable | Completed | Institute of Liver and Biliary Sciences, India | 108 | 2017-04-01 | 2019-07-17 |
| Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders Sodium Benzoate, Sodium Phenylbutyrate - Urea Cycle Disorders, Inborn | Not applicable | Completed | Baylor College of Medicine | 7 | 2014-09-01 | 2018-01-09 |
| Sodium Benzoate for Treatment of Attenuated/Transient Psychosis. A Randomized Placebo-controlled Trial. Sodium Benzoate, Placebo - Attenuated or Transient Psychosis | Phase 2 | Withdrawn | Niuvanniemi Hospital | 2014-02-01 | 2014-04-10 | |
| Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline - Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid | Not applicable | Terminated | The University of Texas Health Science Center, Houston | 42 | 2010-03-01 | 2016-05-13 |
| Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy sodium phenylacetate and sodium benzoate injection 10% / 10%, placebo solution (10% dextrose) - Hepatic Encephalopathy | Phase 2 | Terminated | Amgen | 1 | 2007-12-01 | 2024-12-17 |
| Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders Sodium Benzoate, Sodium Phenylacetate, Sodium Phenylbutyrate - Amino Acid Metabolism, Inborn Errors | Phase 2 | Completed | National Center for Research Resources (NCRR) | 20 | 1985-01-01 | 2005-06-24 |
Urea Cycle Disorders, Inborn (2) · Amino Acid Metabolism, Inborn Errors (1) · Hepatic Encephalopathy (1) · Inflammation (1) · Lymphoma, Follicular (1) · Metabolism, Inborn Errors (1) · Psychotic Disorders (1) · Rare Diseases (1) · Schizophrenia (1) · Sleep Apnea, Obstructive (1)
Amgen (1) · Baylor College of Medicine (1) · Institute of Liver and Biliary Sciences, India (1) · National Center for Research Resources (NCRR) (1) · Niuvanniemi Hospital (1) · Pakistan Institute of Living and Learning (1) · The University of Texas Health Science Center, Houston (1)
United States (3) · Finland (1) · India (1) · Pakistan (1)
Imran B Chaudhry, MD (1) · Jari Tiihonen, MD, PhD (1) · Juan C Marini, DVM., PhD (1) · Sandesh CS Nagamani, MD, FACMG (1) · Saul W. Brusilow (1)