2 completed, 2 terminated, 1 active not recruiting, 1 recruiting. 3 Phase 2, 2 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Terminated 2, Completed 1 |
| Not applicable | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Silibinin: new trials by email Literature Review of Silibinin trials Research Report on Silibinin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET) Silibinin, Placebo - Brain Metastases, Adult, Non Small Cell Lung Cancer | Not applicable | Recruiting | A.O.U. Città della Salute e della Scienza | 70 | 2023-09-01 | 2023-12-15 |
| Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin Silibinin - Brain Metastases, Adult | Not applicable | Active not recruiting | Istituto Clinico Humanitas | 44 | 2023-03-06 | 2025-04-24 |
| Trial of Indole-3-Carbinol and Silibinin Indole-3-Carbinol, Silibinin, Silibin - Smoking | Phase 1 | Completed | Masonic Cancer Center, University of Minnesota | 21 | 2018-11-29 | 2021-08-11 |
| Legalon SIL for the Treatment of HCV Recurrence in Liver Transplanted Patients Silibinin, Placebo - HCV Recurrence After Liver Transplantation | Phase 2 | Terminated | Rottapharm | 14 | 2010-09-01 | 2012-02-17 |
| Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning Silibinin - Amatoxin Poisoning, Amanita Poisoning | Phase 2 | Terminated | Mylan Specialty, LP | 148 | 2009-11-10 | 2022-04-07 |
| Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders Silibinin - Hepatitis C | Phase 2 | Completed | Medical University of Vienna | 70 | 2007-10-01 | 2017-03-27 |
Brain Neoplasms (2) · Breast Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Hepatitis C (1) · Hepatitis C, Chronic (1) · Liver Failure (1) · Mushroom Poisoning (1) · Smoking (1)
A.O.U. Città della Salute e della Scienza (1) · Istituto Clinico Humanitas (1) · Masonic Cancer Center, University of Minnesota (1) · Medical University of Vienna (1) · Mylan Specialty, LP (1) · Rottapharm (1)
Italy (2) · United States (2) · Austria (1)
Naomi Fujioka, MD (1) · Wallis Marsh, MD (1) · Xavier Forns, Dr (1)