8 completed, 1 recruiting. 9 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 8, Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Sevelamer carbonate: new trials by email Literature Review of Sevelamer carbonate trials Research Report on Sevelamer carbonate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluate the Efficacy and Safety of JMKX003002 in End-Stage Renal Disease Patients on Hemodialysis with Hyperphosphatemia JMKX003002 will be administered orally, Sevelamer carbonate - Hyperphosphatemia | Phase 2 | Recruiting | Jemincare | 50 | 2024-12-30 | 2025-02-03 |
| A Study to Evaluate Safety and Efficacy of AP-306 in Hyperphosphatemia Patients AP-306, Sevelamer Carbonate - Chronic Kidney Diseases, Hyperphosphatemia | Phase 2 | Completed | Alebund Pharmaceuticals | 55 | 2023-02-20 | 2024-01-10 |
| A Phase 2 Study to Evaluate the Safety and Efficacy of VS-505(AP301) to Treat Hyperphosphatemia in Hemodialysis Patients VS-505, Sevelamer Carbonate - Hyperphosphatemia | Phase 2 | Completed | Shanghai Alebund Pharmaceuticals Limited | 158 | 2020-10-13 | 2022-10-18 |
| Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapy Tenapanor, Placebo, Phosphate Binder Agents - Hyperphosphatemia | Phase 2 / Phase 3 | Completed | Ardelyx | 236 | 2019-02-28 | 2023-03-06 |
| An Efficacy and Safety Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Participants With Chronic Kidney Disease Placebo, Sevelamer carbonate - Hyperphosphatemia, Chronic Kidney Disease | Phase 2 | Completed | Genzyme, a Sanofi Company | 101 | 2012-05-01 | 2016-07-25 |
| The Effects of Sevelamer Carbonate on Diabetic Nephropathy Sevelamer Carbonate, calcium carbonate - Diabetic Nephropathy | Phase 2 | Completed | Gary Striker | 117 | 2012-02-01 | 2014-04-09 |
| Sevelamer for Reducing Endotoxemia and Immune Activation Sevelamer carbonate - HIV-1 Infection | Phase 2 | Completed | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 40 | 2011-11-01 | 2018-10-11 |
| Effects of Phosphate Binding With Sevelamer in Stage 3 Chronic Kidney Disease Sevelamer carbonate, Placebo - Kidney Failure, Chronic, Cardiovascular Diseases | Phase 2 | Completed | University Hospital Birmingham NHS Foundation Trust | 120 | 2009-02-01 | 2011-11-23 |
| Randomized Study Comparing Genz-644470, Placebo, and Sevelamer Carbonate in Chronic Kidney Disease Patients on Hemodialysis Placebo, Genz-644470, Sevelamer carbonate - Kidney Failure, Chronic | Phase 2 | Completed | Genzyme, a Sanofi Company | 349 | 2009-02-01 | 2015-05-01 |
Hyperphosphatemia (6) · Renal Insufficiency, Chronic (3) · Kidney Failure, Chronic (2) · Cardiovascular Diseases (1) · Diabetic Nephropathies (1)
Genzyme, a Sanofi Company (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Alebund Pharmaceuticals (1) · Ardelyx (1) · Gary Striker (1) · Jemincare (1) · Shanghai Alebund Pharmaceuticals Limited (1) · University Hospital Birmingham NHS Foundation Trust (1)
United States (5) · China (3) · France (1) · Germany (1) · Lithuania (1) · Poland (1) · Puerto Rico (1) · United Kingdom (1)
Charles J Ferro, BSc (Hons), MBChB, FRCP, MD (1) · David P Rosenbaum, PhD (1) · Gary Striker, MD (1) · Li Wang, MD (1) · Netanya Sandler, MD (1) · Rajesh Gandhi, MD (1)
PMID 40576086, PMID 21288351, PMID 22461535, PMID 24864123, PMID 33766811, PMID 38323855, PMID 38453435
2008 (1), U01AI068636 (1)