2 terminated, 1 active not recruiting, 1 withdrawn. 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Terminated 2, Active not recruiting 1, Withdrawn 1 |
Follow Sephb4-Hsa: new trials by email Literature Review of Sephb4-Hsa trials Research Report on Sephb4-Hsa
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| sEphB4-HSA in Treating Participants With BCG-Unresponsive or Refractory Bladder Cancer Pharmacokinetic Study, Recombinant EphB4-HSA Fusion Protein - Recurrent Bladder Carcinoma, Bladder Cancer Stage 0 | Phase 1 | Withdrawn | University of Southern California | 2023-08-01 | 2023-06-26 | |
| EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia Cytarabine, Laboratory Biomarker Analysis, Recombinant EphB4-HSA Fusion Protein - Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Blasts 5 Percent or More of Bone Marrow Nucleated Cells | Phase 1 | Terminated | University of Southern California | 3 | 2018-05-09 | 2021-11-30 |
| sEphB4-HSA Before Surgery in Treating Patients With Bladder Cancer, Prostate Cancer, or Kidney Cancer Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis, Radical Cystectomy - Infiltrating Bladder Urothelial Carcinoma, Recurrent Bladder Carcinoma | Phase 1 | Terminated | University of Southern California | 2 | 2016-08-02 | 2021-11-24 |
| Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors Cisplatin, Docetaxel, Gemcitabine Hydrochloride - Head and Neck Squamous Cell Carcinoma, Metastatic Pancreatic Adenocarcinoma | Phase 1 | Active not recruiting | University of Southern California | 61 | 2015-09-03 | 2026-04-29 |
Urinary Bladder Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Renal Cell (1) · Gallbladder Neoplasms (1) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (1) · Leukemia, Myeloid, Acute (1) · Myelodysplastic-Myeloproliferative Diseases (1) · Pancreatic Neoplasms (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Prostatic Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1)
University of Southern California (4)
United States (4)
Akil Merchant, MD (1) · Anthony El-Khoueiry (1) · David I Quinn, MD (1) · Monish Aron, MD (1)
P30CA014089 (4)