7 completed, 2 recruiting, 1 active not recruiting, 1 enrolling by invitation. 10 Not applicable, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 6, Recruiting 2, Enrolling by invitation 1, Not yet recruiting 1 |
| Phase 2 | 1 | Terminated 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Saposins: new trials by email Literature Review of Saposins trials Research Report on Saposins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Serratus and Pectoralis II Plane Block Versus Pectoralis II Alone on Acute Postoperative Pain After Mastectomy Serratus Anterior Plane Block (SAPB) group, Pectoral nerve block (PECS) - Mastectomy, Mastectomy Plus Axillary Lymph Node Dissection | Not applicable | Not yet recruiting | Lebanese American University | 80 | 2026-12-01 | 2026-10-19 |
| Comparison of the Analgesic Efficacy of Ultrasound-guided Retrolaminar Block Versus Serratus Anterior Plane Block in Patients Undergoing Radical Mastectomy Serratus Anterior Plane Block (SAPB) group, Retrolaminar block group - Serratus Anterior Plane Block | Phase 4 | Active not recruiting | Ain Shams University | 90 | 2026-05-17 | 2026-06-16 |
| Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block SAPB + PECS II Technique, Erector Spinae Plane Block - Pain Management in Breast Surgery, Pain After Surgery | Not applicable | Completed | Kayseri City Hospital | 70 | 2026-04-10 | 2026-07-21 |
| SPSIP Block vs SAP Block for Post-VATS Pain Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block - Postoperative Pain, Video-Assisted Thoracoscopic Surgery | Completed | Firat University | 80 | 2026-03-13 | 2026-10-02 | |
| Comparison of SPSIP Block and SAP Block in Non-Intubated Uniportal VATS. Serratus Anterior Plane Block (SAPB) group, Serratus posterior superior intercostal plane block group - This Study Evaluates the Effects of Different Fascial Plane Blocks on Intraoperative Anesthesia and Analgesic Consumption in Non-intubated VATS Procedures | Not applicable | Recruiting | Firat University | 70 | 2026-01-16 | 2026-02-27 |
| Intrathecal Morphine for Recovery and Outcomes After VATS Intrathecal Morphine, Serratus Anterior Plane Block (SAPB) group, Dexmedetomidine - Postoperative Pain Management in Video-Assisted Thoracoscopic Surgery | Not applicable | Completed | Ataturk University | 64 | 2025-12-01 | 2026-09-03 |
| Erector Spinae Plane Block Versus Serratus Anterior Plane Block in VATS Erector Spinae Plane Block (ESPB) group, Serratus Anterior Plane Block (SAPB) group - Video Assisted Thoracic Surgery (VATS) | Not applicable | Recruiting | Ain Shams University | 40 | 2025-05-01 | 2025-05-30 |
| Comparative Study Between Erector Spinae Plane Block Versus Combined Pectoralis and Serratus Interfascial Plane Blocks for Post-operative Analgesia After Thoracic Surgery. Erector spinae plane block, Combined pectoralis and serratus anterior plane blocks - Post Operative Pain, Thoracic Surgery | Not applicable | Enrolling by invitation | Minia University | 66 | 2025-04-01 | 2026-10-08 |
| We Have Two Groups. Both Groups Received a Deep Serratus Anterior Plane Block. One Group Had a Catheter for Continuous Infusion, While the Other Received IV Analgesics Postoperatively. Analgesic Effects Between the Two Groups Were Compared Serratus Anterior Plane Block (SAPB) group, DSAPB - Pain Management After Surgery, Regional Anaesthesia | Not applicable | Completed | Istanbul Medeniyet University | 50 | 2025-01-26 | 2025-07-10 |
| Parasternal Block Added to Serratus Anterior Plane Block in Breast Reduction Surgery Serratus Anterior Plane Block (SAPB), Serratus Anterior Plane Block (SAPB) and parasternal intercostal plane block - Breast Reduction, Postoperative Pain | Not applicable | Completed | Zonguldak Bulent Ecevit University | 90 | 2024-05-01 | 2026-02-25 |
| Serratus Anterior Plan Block and Postoperative Pain in Patients Who Underwent Minimally Invasive Cardiac Surgery SAPB (Serratus Anterior Plan) Block - Morphine Consumption, Pain | Not applicable | Completed | Kahramanmaras Sutcu Imam University | 40 | 2023-09-01 | 2024-04-17 |
| Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy Control group, Serratus Anterior Plane Block (SAPB) group, Erector Spinae Plane Block (ESPB) group - Ultrasound, Serratus Anterior Plane Block | Not applicable | Completed | Tanta University | 105 | 2023-07-01 | 2025-03-06 |
| Exploratory fMRI Study on the Treatment for Impulsive Aggression in Children With ADHD Functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Spectroscopy (MRS), Point Subtraction Aggression Paradigm (PSAP) Task - Attention Deficit Hyperactivity Disorder (ADHD), Impulsive Aggression | Phase 2 | Terminated | Supernus Pharmaceuticals, Inc. | 7 | 2019-05-30 | 2025-05-02 |
Pain, Postoperative (5) · Pain (2) · Agnosia (1) · Attention Deficit Disorder with Hyperactivity (1) · Breast Neoplasms (1)
Ain Shams University (2) · Firat University (2) · Ataturk University (1) · Istanbul Medeniyet University (1) · Kahramanmaras Sutcu Imam University (1) · Kayseri City Hospital (1) · Lebanese American University (1) · Minia University (1) · Supernus Pharmaceuticals, Inc. (1) · Tanta University (1) · Zonguldak Bulent Ecevit University (1)
Turkey (Türkiye) (7) · Egypt (4) · Lebanon (1) · United States (1)
Ahmet Aksu, MD (1) · Nuray Uzun (1) · Yavuz Orak (1)