We Have Two Groups. Both Groups Received a Deep Serratus Anterior Plane Block. One Group Had a Catheter for Continuous Infusion, While the Other Received IV Analgesics Postoperatively. Analgesic Effects Between the Two Groups Were Compared

NCT07053397 — Not applicable, Completed, 50 participants, Istanbul Medeniyet University

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A Comparative Study on the Analgesic Efficacy of Ultrasound-Guided Continuous Catheter-Based Deep Serratus Anterior Plane Block Versus Single-Injection Deep Serratus Anterior Plane Block in Patients Undergoing Breast Surgery

Registry	NCT07053397, acronym DSAPB
Status	Completed
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: double, prevention
Enrollment	50 (Actual)
Sponsor	Istanbul Medeniyet University (Other)
Conditions	Pain Management After Surgery, Regional Anaesthesia
Interventions	Serratus Anterior Plane Block (SAPB) group, DSAPB (Procedure)
Dates	start 2025-01-26, primary completion 2025-04-26, completion 2025-05-26, first posted 2025-07-08, last updated 2025-07-10
Locations	1 site in Turkey (Türkiye)

-Summary

The aim of this observational study is to compare the analgesic efficacy of continuous infusion via peripheral catheter versus single-shot serratus anterior plane block in women aged 18 to 80 undergoing breast-conserving surgery. The main questions it aims to answer are: Does continuous serratus anterior plane block via peripheral catheter provide superior postoperative analgesic efficacy compared to single-shot serratus anterior plane block? Second question is: Does continuous infusion via catheter in peripheral nerve blocks reduce the amount of intravenous analgesics consumed and improve patient comfort?

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+Arms and interventions

Arm	Type	Interventions	Description
SAPB	Active comparator	Procedure: Serratus Anterior Plane Block (SAPB) group	The SAPB arm receives single shot deep serratus anterior plane block before surgery. Also receives iv analgesic treatment after post-operative duration.
DSAPB	Experimental	Procedure: Serratus Anterior Plane Block (SAPB) group; Procedure: DSAPB	The DSAPB arm receives deep serratus anterior plane block and cathather replacement before surgery. After surgery, the arm takes continous analgesic treatment via periferic block cathather.

Serratus Anterior Plane Block (SAPB) group (Procedure), also known as serratus anterior plane block: The SAP block, which is among the chest wall blocks, provides its effect by blocking the lateral cutaneous branches of the T2-T9 intercostal nerves, n. intercostobrachial , n. longus thoracicus , n. thoracodorsal. SAP block can be performed in two ways: superficial and deep. The deep SAP block is administered between the serratus anterior and intercostal muscles, at the intersection point of the anterior axillary line and the level of the nipple (at the level of the 4th-5th ribs). It has a wide range of use for postoperative pain management in trauma surgery, cardiac surgery, thoracic surgery and breast surgery.
DSAPB (Procedure), also known as serratus anterior plane peripheral block cathather replacement: The SAP block, which is among the chest wall blocks, provides its effect by blocking the lateral cutaneous branches of the T2-T9 intercostal nerves, n. intercostobrachial , n. longus thoracicus , n. thoracodorsal. SAP block can be performed in two ways: superficial and deep. The deep SAP block is administered between the serratus anterior and intercostal muscles, at the intersection point of the anterior axillary line and the level of the nipple (at the level of the 4th-5th ribs). Following hydrodissection between the serratus anterior and intercostal muscles, a single-shot injection is administered. Subsequently, a peripheral nerve block catheter is placed in the same region under ultrasound guidance.

+Outcome measures

Primary outcomes

Numeric Rating Scale [Until discharge after surgery, during an average hospital stay of approximately 24 hours.]: 1 - 10 1 is minimum pain 10 is maximum pain the lower scale is better for pain management.

+Eligibility

Sex: Female, ages: 18 Years to 80 Years

Inclusion Criteria:

* Female patients aged 18 to 80 years
* Scheduled for breast-conserving surgery
* Classified as American Society of Anesthesiologists (ASA) physical status I, II, or III

Exclusion Criteria:

* Patients with coagulopathy
* Patients with wounds or infections at the block site
* Patients with known allergy to local anesthetic agents
* Patients with mental retardation or limited cooperation
* Patients who do not consent to participate in the study
* Patients who, for any reason, discontinue participation during the course of the study

+Locations (1)

Facility	City	Country	Status
Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi	Istanbul, Kadıköy	Turkey (Türkiye)