10 terminated. 10 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Terminated 10 |
| Phase 1 | 4 | Terminated 4 |
Follow SABR: new trials by email Literature Review of SABR trials Research Report on SABR
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for Oligometastatic Pancreatic Cancer Chemotherapy, Stereotactic Body Radiation Therapy, Computed Tomography - Metastatic Pancreatic Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8 | Phase 2 | Terminated | Mayo Clinic | 2 | 2023-07-18 | 2026-06-18 |
| Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer Biospecimen Collection, Bone Scan, Computed Tomography - Metastatic Urothelial Carcinoma, Platinum-Resistant Urothelial Carcinoma | Phase 2 | Terminated | National Cancer Institute (NCI) | 1 | 2022-11-22 | 2025-08-17 |
| NBTXR3, Radiation Therapy, and Pembrolizumab for the Treatment of Recurrent or Metastatic Head and Neck Squamous Cell Cancer Hafnium Oxide-containing Nanoparticles NBTXR3, Hypofractionated Radiation Therapy, Pembrolizumab - Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 2 | Terminated | M.D. Anderson Cancer Center | 14 | 2021-04-07 | 2026-01-23 |
| Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid Malignancies Anti-CTLA4 Monoclonal Antibody BMS-986218, Nivolumab, Stereotactic Body Radiation Therapy - Advanced Lung Carcinoma, Advanced Malignant Solid Neoplasm | Phase 1 / Phase 2 | Terminated | M.D. Anderson Cancer Center | 13 | 2021-03-29 | 2026-03-03 |
| Stereotactic Ablative Radiotherapy for Oligo-Progressive Non Small Cell Lung Cancer SABR, Standard of care - Lung Cancer Metastatic | Phase 2 | Terminated | Centre hospitalier de l'Université de Montréal (CHUM) | 52 | 2021-01-05 | 2026-09-28 |
| Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer Bintrafusp Alfa, Quality-of-Life Assessment, Questionnaire Administration - Recurrent Head and Neck Squamous Cell Carcinoma, Second Primary Squamous Cell Carcinoma of the Head and Neck | Phase 1 / Phase 2 | Terminated | M.D. Anderson Cancer Center | 3 | 2020-03-18 | 2024-11-07 |
| Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner Durvalumab, Modified Radical Neck Dissection, Quality-of-Life Assessment - Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC (American Joint Committee on Cancer) v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 1 / Phase 2 | Terminated | Jonsson Comprehensive Cancer Center | 19 | 2018-10-04 | 2023-11-18 |
| Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Durvalumab, Laboratory Biomarker Analysis, Stereotactic Body Radiation Therapy - Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Terminated | University of Washington | 6 | 2018-05-17 | 2023-06-12 |
| Clinical Trial Comparing TACE With TACE + SABR in Stage BCLC B HCC (HepSTAR) Trans-arterial Chemo-Embolization, Doxorubicin, Stereotactic Ablative Radiotherapy - Liver Neoplasms, Hepatocellular Cancer | Phase 2 | Terminated | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 3 | 2017-02-20 | 2017-11-07 |
| Nivolumab and Stereotactic Ablative Radiation Therapy (SAbR) for Metastatic Clear Cell Renal Cell Carcinoma Nivolumab, SAbR - Metastatic Clear Cell Renal Cell Carcinoma | Phase 2 | Terminated | University of Texas Southwestern Medical Center | 7 | 2016-06-20 | 2022-08-08 |
Squamous Cell Carcinoma of Head and Neck (4) · Liver Neoplasms (2) · Adrenal Gland Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Transitional Cell (1) · Clear-cell metastatic renal cell carcinoma (1) · Lung Neoplasms (1) · Neoplasm Metastasis (1) · Oropharyngeal Neoplasms (1) · Pancreatic Neoplasms (1) · Urinary Bladder Neoplasms (1)
M.D. Anderson Cancer Center (3) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Jonsson Comprehensive Cancer Center (1) · Mayo Clinic (1) · National Cancer Institute (NCI) (1) · University of Texas Southwestern Medical Center (1) · University of Washington (1)
United States (8) · Belgium (1) · Canada (1)
Bertrand Routy, MD PhD (1) · Cristina P. Rodriguez (1) · Himanshu Nagar (1) · Houda Bahig, MD PhD (1) · James Welsh (1) · Jay Reddy (1) · Michael S. Rutenberg, MD, PhD (1) · Raquibul Hannan, MD, PhD (1) · Renata Ferrarotto (1) · Robert Chin (1)
PMID 33720067, PMID 40950337, PMID 42032732
P30CA015704 (1), U10CA180821 (1)