6 completed, 4 unknown, 2 not yet recruiting, 2 recruiting. 10 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 4, Unknown 3, Not yet recruiting 2, Active not recruiting 1 |
Follow rotational atherectomy: new trials by email Literature Review of rotational atherectomy trials Research Report on rotational atherectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravascular Lithotripsy Versus Rotational Atherectomy for Severe Coronary Artery Calcification: A Prospective, Multicenter, Non-inferiority Randomized Controlled Trial intravascular lithotripsy, rotational atherectomy - Coronary Artery Calcifications, Intravascular Lithotripsy | Not applicable | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 190 | 2026-10-01 | 2026-08-06 |
| Intravascular Lithotripsy With or Without Rotational Atherectomy for Coronary Calcified Nodule Treatment Intravascular lithotripsy, Rotational atherectomy - Coronary Artery Disease, Coronary Calcification | Not applicable | Active not recruiting | Annapoorna Kini | 120 | 2025-10-06 | 2026-10-08 |
| Safety and Effectiveness of the Single-Use Coronary Forward Intravascular Lithotripsy Catheter Combined With the Intravascular Lithotripsy Therapy Device Intravascular Lithotripsy, Rotational Atherectomy - Coronary Arterial Disease | Not applicable | Not yet recruiting | Spectrumedics Medical Technology(Shanghai)Co.,Ltd | 180 | 2025-10-01 | 2025-08-07 |
| Intravascular Lithotripsy in Comparison to Rotational Atherectomy: An Evaluation by OFDI Intravascular Lithotripsy, Rotational Atherectomy - Intravascular Lithotripsy; Rotational Atherectomy; OFDI | Not applicable | Unknown | University Hospital, Clermont-Ferrand | 178 | 2022-08-04 | 2022-08-10 |
| Rotational Atherectomy Combined With Cutting Balloon to Optimize Stent Expansion in Calcified Lesions rotational atherectomy, cutting balloon, plain old balloon - Coronary Artery Disease, Atherosclerosis | Not applicable | Completed | Samin Sharma, M.D., F.A.C.C., M.S.C.A.I. | 60 | 2022-05-13 | 2024-05-22 |
| Intravascular Lithotripsy and/or Mechanical Debulking for Severely Calcified Coronary Artery Lesions Intravascular Lithotripsy - Coronary Artery Disease, Myocardial Infarction | Unknown | SS Annunziata Hospital, Savigliano | 400 | 2021-10-01 | 2021-08-23 | |
| IVL and RA in Treatment of Balloon-crossable Severely Calcified Coronary Lesions Rotational atherectomy, Intravascular lithotripsy - Coronary Calcification | Completed | Assiut University | 101 | 2021-05-01 | 2022-08-02 | |
| ROVUS Asia Registry (Evaluate Safety and Effectiveness of Rotational Atherectomy and Intravascular Ultrasound for Heavily Calcified Coronary Lesion) Rotational Atherectomy - Coronary Artery Calcification | Recruiting | National Heart Centre Singapore | 1000 | 2021-03-10 | 2021-04-23 | |
| Atherectomy vs Intravascular Lithotripsy Rotational atherectomy - Coronary Artery Disease | Not applicable | Unknown | University of Roma La Sapienza | 100 | 2019-09-01 | 2019-07-12 |
| Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice Rotational atherectomy - Atherosclerosis, Coronary, Coronary Stenosis | Recruiting | Seung-Jung Park | 500 | 2018-09-04 | 2026-01-02 | |
| Rota China Registry Rotational Atherectomy - Coronary Artery Disease | Completed | Beijing Anzhen Hospital | 980 | 2018-07-18 | 2023-08-08 | |
| Revolution™ Peripheral Atherectomy System for Lower Extremity Peripheral Arterial Revascularization Revolution™ Peripheral Atherectomy System - Peripheral Artery Disease | Not applicable | Completed | Rex Medical | 121 | 2017-06-07 | 2020-11-02 |
| Side Branch FFR After Provisional Stenting Rotational atherectomy, Cutting Balloon Angioplasty - Coronary Artery Disease | Not applicable | Completed | Icahn School of Medicine at Mount Sinai | 71 | 2017-05-02 | 2020-05-14 |
| Efficacy CompariSon of Pre-stenting Atherectomy Versus Scoring ballooN for calcifieD Coronary Lesions Coronary Lesions Rotational atherectomy, Orbital atherectomy, Scoring balloon system - Atherosclerosis, Coronary Artery Disease | Not applicable | Unknown | North Texas Veterans Healthcare System | 30 | 2016-06-01 | 2017-04-07 |
| The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC) Rotational Atherectomy, Cutting/Scoring Balloon - Coronary Atherosclerosis Due to Severely Calcified Coronary Lesion | Not applicable | Completed | Segeberger Kliniken GmbH | 200 | 2014-09-01 | 2020-04-01 |
Coronary Artery Disease (8) · Atherosclerosis (3) · Coronary Stenosis (1) · Myocardial Infarction (1) · Peripheral Arterial Disease (1)
Annapoorna Kini (1) · Assiut University (1) · Beijing Anzhen Hospital (1) · Icahn School of Medicine at Mount Sinai (1) · National Heart Centre Singapore (1) · North Texas Veterans Healthcare System (1) · Rex Medical (1) · SS Annunziata Hospital, Savigliano (1) · Samin Sharma, M.D., F.A.C.C., M.S.C.A.I. (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Segeberger Kliniken GmbH (1) · Seung-Jung Park (1) · Spectrumedics Medical Technology(Shanghai)Co.,Ltd (1) · University Hospital, Clermont-Ferrand (1) · University of Roma La Sapienza (1)
United States (4) · China (2) · France (1) · Germany (1) · Japan (1) · Netherlands (1) · Singapore (1) · South Korea (1)
Annapoorna Kini, MD, MRCO, FACC (1) · Annapoorna S Kini, MD (1) · Emmanouil S Brilakis, MD, PhD (1) · Iannis Karalis, Doctor (1) · Jeffrey G Carr, MD (1) · Jerrold Grodin, MD (1) · Johan W Jukema, professor (1) · Kenneth Ouriel, MD (1) · Khung Keong Yeo (1) · Mohamed AA Mousa, Doctor (1) · Mohamed Abdel-Wahab, MD (1) · Mohamed Abdelghany, professor (1) · Salma M Taha, Lecturer (1) · Samin K Sharma, MD (1)
PMID 30354632, PMID 33641372, PMID 34624496, PMID 38483633, PMID 39223992, PMID 41609534