8 completed, 2 terminated, 1 recruiting, 1 unknown. 12 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 12 | Completed 8, Terminated 2, Recruiting 1, Unknown 1 |
Follow Rituxan: new trials by email Literature Review of Rituxan trials Research Report on Rituxan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD Rituximab (R), Eculizumab (Soliris®), Ravulizumab - NMOSD | Phase 4 | Recruiting | Massachusetts General Hospital | 540 | 2026-09-01 | 2026-09-24 |
| Maintenance of ANCA Vasculitis Remission by Intermittent Rituximab Dosing Rituximab - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Phase 4 | Terminated | Massachusetts General Hospital | 115 | 2016-06-01 | 2023-07-27 |
| Rituximab for the Otolaryngologic Manifestations of Granulomatosis With Polyangiitis Rituximab, Placebo - Granulomatosis With Polyangiitis (Wegener's Granulomatosis) | Phase 4 | Terminated | Hospital for Special Surgery, New York | 3 | 2015-12-01 | 2018-03-22 |
| Low-dose Glucocorticoid Vasculitis Induction Study Rituximab, Glucocorticoids - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Microscopic Polyangiitis | Phase 4 | Unknown | Chiba University | 140 | 2014-10-01 | 2021-01-27 |
| Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis Glucocorticoids, Rituximab - Granulomatosis With Polyangiitis, Microscopic Polyangiitis | Phase 4 | Completed | Massachusetts General Hospital | 20 | 2014-06-01 | 2021-06-25 |
| Rituximab at Low dosE for neuromyelitiS optiCa spectrUm disordEr (RESCUE) Rituximab - Neuromyelitis Optica Spectrum Disorder | Phase 4 | Completed | Tang-Du Hospital | 108 | 2014-04-01 | 2020-10-19 |
| Study Evaluating Rapid Infusion Rituximab in Patients With Autoimmune Diseases Rituximab Infusion - Multiple Sclerosis | Phase 4 | Completed | Wake Forest University Health Sciences | 19 | 2013-02-01 | 2018-09-07 |
| Rituximab (RTX) Therapy in Patients With Active TAO Rituximab, Iv Methylprednisolone, peroral methylprednisolone and Methotrexate - Ophthalmopathy, Thyroid-Associated | Phase 4 | Completed | Göteborg University | 38 | 2011-12-01 | 2025-03-26 |
| Desensitization in Kidney Transplantation plasmapheresis, Bortezomib, Rituximab - HLA Sensitization | Phase 4 | Completed | University of Cincinnati | 44 | 2009-05-01 | 2016-04-01 |
| Rituximab in Progressive Immunoglobulin A (IgA) Nephropathy Intravenous Rituximab, ACE/ARB, Omega-3 Fatty Acid Fish Oil Supplement - IgA Nephropathy | Phase 4 | Completed | Mayo Clinic | 34 | 2009-02-01 | 2017-02-01 |
| Randomized Trial of Induction Therapies in High Immunological Risk Kidney Transplant Recipients Rabbit Antithymocyte Globulin, Velcade, Rituxan - Kidney Transplantation | Phase 4 | Completed | University of Cincinnati | 40 | 2008-09-01 | 2016-01-20 |
| A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies. rituximab, Methotrexate, Corticosteroid or NSAID - Rheumatoid Arthritis | Phase 4 | Completed | Hoffmann-La Roche | 40 | 2007-06-01 | 2014-11-04 |
Granulomatosis with Polyangiitis (3) · Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (2) · Microscopic Polyangiitis (2) · Arthritis, Rheumatoid (1) · Glomerulonephritis, IGA (1) · Graves Ophthalmopathy (1) · Multiple Sclerosis (1) · Neuromyelitis Optica (1) · Proteinuria (1) · Rejection, Psychology (1)
Massachusetts General Hospital (3) · University of Cincinnati (2) · Chiba University (1) · Göteborg University (1) · Hoffmann-La Roche (1) · Hospital for Special Surgery, New York (1) · Mayo Clinic (1) · Tang-Du Hospital (1) · Wake Forest University Health Sciences (1)
United States (8) · Germany (1) · Japan (1) · South Korea (1) · Sweden (1)
E. Steve Woodle, MD (2) · Fernando C. Fervenza, M.D. (1) · Helena Filipsson, Ass Prof (1) · Hiroshi Nakajima, M.D., Ph.D (1) · Hongzeng Li (1) · John H Stone, MD (1) · John L Niles, MD (1) · LeAnne D Kennedy, PharmD (1) · Philippe-Antoine Bilodeau, MD (1) · Robert F Spiera, MD (1)
PMID 26032537, PMID 27821627, PMID 27889300, PMID 29247107, PMID 33164993, PMID 34061144, PMID 37734880, PMID 38123922