5 completed, 1 terminated. 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 1 | Completed 1 |
Follow rFIXFc: new trials by email Literature Review of rFIXFc trials Research Report on rFIXFc
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An International Study to Evaluate the Real-world Effectiveness and Usage of Alprolix in Patients With Haemophilia B Alprolix - Hemophilia B | Completed | Swedish Orphan Biovitrum | 151 | 2019-09-12 | 2025-09-29 | |
| Fc factOrs and Real-World hemophiliA Patient-ReporteD Outcomes rFVIIIFc, rFIXFc, non-Fc FVIII replacement products - Hemophilia A, Hemophilia B | Terminated | Bioverativ Therapeutics Inc. | 3 | 2015-07-01 | 2020-12-19 | |
| Study to Determine the Safety and Efficacy of rFIXFc in Previously Untreated Males With Severe Hemophilia B rFIXFc - Hemophilia B | Phase 3 | Completed | Bioverativ, a Sanofi company | 33 | 2014-11-13 | 2022-03-25 |
| Study of Recombinant Coagulation Factor IX Fc Fusion Protein, BIIB029, in Previously Treated Pediatric Participants With Hemophilia B rFIXFc, FIX - Hemophilia B | Phase 3 | Completed | Bioverativ Therapeutics Inc. | 30 | 2012-06-01 | 2020-12-19 |
| Long-Term Safety and Efficacy of rFIXFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia B rFIXFc - Severe Hemophilia B | Phase 3 | Completed | Bioverativ Therapeutics Inc. | 120 | 2011-12-08 | 2020-12-19 |
| Phase I/IIa Study of FIXFc in Hemophilia B Patients rFIXFc - Hemophilia B | Phase 1 | Completed | Bioverativ Therapeutics Inc. | 10 | 2008-04-01 | 2020-12-19 |
Hemophilia B (6) · Blood Coagulation Disorders (1) · Coagulation Protein Disorders (1) · Genetic Diseases, Inborn (1) · Hematologic Diseases (1) · Hemophilia A (1) · Hemorrhagic Disorders (1)
Bioverativ Therapeutics Inc. (4) · Bioverativ, a Sanofi company (1) · Swedish Orphan Biovitrum (1)
United States (5) · Ireland (4) · United Kingdom (4) · Australia (3) · Italy (3) · Netherlands (3) · Sweden (3) · France (2) · Poland (2) · South Africa (2) · Belgium (1) · Brazil (1) · Canada (1) · China (1) · Czechia (1)
PMID 36848635, PMID 22110246, PMID 28159192, PMID 30656283, PMID 34242387, PMID 37283819, PMID 38922990