17 completed, 2 withdrawn, 1 active not recruiting, 1 terminated. 10 Not applicable, 4 Phase 3, 3 Phase 2, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Completed 9, Active not recruiting 1 |
| Phase 3 | 4 | Completed 3, Withdrawn 1 |
| Phase 2 | 3 | Completed 3 |
| Phase 4 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
Follow Restylane: new trials by email Literature Review of Restylane trials Research Report on Restylane
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Randomized Masked Trial of Injectable Cross-Linked Hyaluronic Acid for Moderate-to-Severe Nasolabial Folds Intense, Restylane - Nasolabial Fold Wrinkles | Not applicable | Active not recruiting | Chongqing Jinsaixing Medical Technology Co., Ltd | 356 | 2025-02-24 | 2026-01-26 |
| Clinical Trial of Cross-linked Hyaluronic Acid Dermal Filler Formaderm Young, Restylane - Hyaluronic Acid, Dermal Fillers | Not applicable | Completed | Maxigen Biotech Inc. | 320 | 2018-08-27 | 2023-07-07 |
| Pain and Safety of Restylane With and Without Lidocaine for Correction of Moderate and Severe Nasolabial Folds Restylane Lidocaine, Restylane - Nasolabial Fold | Not applicable | Completed | Galderma R&D | 70 | 2017-02-08 | 2023-06-01 |
| Restylane Defyne Compared to Restylane for Correction of Moderate to Severe Nasolabial Folds Restylane Defyne, Restylane - Nasolabial Folds in Chinese Population | Not applicable | Completed | Galderma R&D | 175 | 2017-01-16 | 2023-11-03 |
| Safety and Efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine for Facial Augmentation in Asian Population Restylane, Perlane - Healthy Volunteers | Not applicable | Completed | Galderma R&D | 100 | 2015-12-01 | 2022-08-26 |
| Multicenter Double-Blind Randomized Split-Face Study to Evaluate Revanesse® Ultra vs Restylane® for Correction of NLF Revanesse Ultra, Restylane - Nasolabial Fold Correction | Not applicable | Completed | Prollenium Medical Technologies Inc. | 163 | 2015-05-01 | 2018-02-22 |
| Efficacy and Safety of Restylane Perlane Compared to Restylane for Correction of Moderate and Severe Nasolabial Folds Restylane Perlane, Restylane - Nasolabial Folds in Chinese Population | Not applicable | Completed | Galderma R&D | 100 | 2015-05-01 | 2022-08-26 |
| A Post Market Evaluation After Treatment of Nasolabial Folds Restylane - Nasolabial Folds | Not applicable | Completed | Galderma R&D | 114 | 2014-07-01 | 2022-08-25 |
| Intraoperative Hyaluronic Acid Gel Injection for Improvement of Scar Quality Following Reduction Mammaplasty Hyaluronic acid gel, Saline - Cicatrix | Phase 3 | Withdrawn | Nova Scotia Health Authority | 2014-01-01 | 2024-08-21 | |
| Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease Hyaluronic Acid Gel injection, Saline injection - Thyroid Eye Disease | Phase 4 | Terminated | University of California, Los Angeles | 2 | 2013-12-01 | 2021-10-04 |
| Hyaluronic Acid Gels for Lower Lid Retraction Hyaluronic acid, Saline - Ectropion | Phase 4 | Withdrawn | University of California, Los Angeles | 2013-02-01 | 2014-12-03 | |
| Clinical Study to Evaluate the Efficacy and Safety of Dermalax(Deep) in Correction of Nasolabial Folds Dermalax(Deep), Restylane - Correction of Nasolabial Folds | Phase 3 | Completed | Across Co., Ltd. | 66 | 2012-12-01 | 2014-07-02 |
| Outcomes and Patient Experience After Soft Tissue Dermal Filler Injections hyaluronic acid or calcium hydroxylapatite filler - Rhytids, Wrinkles | Completed | The New York Eye & Ear Infirmary | 20 | 2009-11-01 | 2012-05-01 | |
| Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds hyaluronic acid with metallic cannula or standard needle., Hyaluronic acid injected with the new tool. - Wrinkles | Phase 2 | Completed | Hexsel Dermatology Clinic | 25 | 2009-07-01 | 2020-10-01 |
| Combined Restylane and Triamcinolone Acetonide Injections for the Treatment of Alopecia Areata Intralesional Triamcinolone Acetonide 10 mg/mL (Kenalog-10), Restylane - Alopecia Areata | Phase 2 | Completed | University of Minnesota | 14 | 2009-03-01 | 2021-01-12 |
| Clinical Study to Evaluate the Correction of Wrinkles and Folds and Safety of YVOIRE Classic Versus Restylane in Nasolabial Fold Intradermal Injection HA IDF (YVOIRE classic), Restylane - Temporary Correction of Wrinkles | Not applicable | Completed | LG Life Sciences | 58 | 2009-01-01 | 2019-12-18 |
| A Study to Compare the Safety and Effectiveness of a Non-FDA Approved Device Dermal Gel Extra (DGE) and an FDA Approved Device for the Correction of Nasolabial Folds (NLFs) Dermal Gel Extra (DGE), Restylane, EMLA Cream - Facial Wrinkles at the Nasolabial Folds | Phase 3 | Completed | Genzyme, a Sanofi Company | 140 | 2007-05-01 | 2015-04-22 |
| Safety and Effectiveness of Aquamid as Compared to Restylane for the Aesthetic Treatment of Nasolabial Folds Aquamid, Restylane - Facial Wrinkles | Not applicable | Completed | Contura | 315 | 2006-12-01 | 2009-10-08 |
| Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds CosmetaLife, Restylane - Facial Wrinkles | Phase 2 | Completed | Cosmeta | 145 | 2006-10-01 | 2011-06-27 |
| A Study to Determine How Long Restylane® Will Last After Initial Treatment With 2 Different Re-treatment Schedules. Restylane - Rhytids | Phase 4 | Completed | Medicis Aesthetics, Inc. | 75 | 2005-11-01 | 2011-09-22 |
Showing 20 of 21. Sign in to see all of them.
Alopecia Areata (1) · Cicatrix (1) · Ectropion (1) · Graves Ophthalmopathy (1) · Keratoconjunctivitis Sicca (1) · Patient Satisfaction (1) · Thyroid Diseases (1)
Galderma R&D (5) · University of California, Los Angeles (2) · Across Co., Ltd. (1) · Chongqing Jinsaixing Medical Technology Co., Ltd (1) · Contura (1) · Cosmeta (1) · Genzyme, a Sanofi Company (1) · Hexsel Dermatology Clinic (1) · LG Life Sciences (1) · Maxigen Biotech Inc. (1) · Medicis Aesthetics, Inc. (1) · Mentor Worldwide, LLC (1) · Nova Scotia Health Authority (1) · Prollenium Medical Technologies Inc. (1) · The New York Eye & Ear Infirmary (1)
United States (9) · China (6) · Brazil (1) · South Korea (1) · Taiwan (1)
Q-Med AB (2) · Anthony P Sclafani, MD (1) · Beom Joon Kim, PhD (1) · Daniel B Rootman, MD, MSc (1) · Daniel Rootman (1) · David B. Masters, Ph.D. (1) · Doris Hesxel, MD (1) · Fredric Brandt, MD (1) · Jong Hoon Lee, PhD (1) · Maria Hordinsky, MD (1) · Michael Bezuhly, MD MSc SM FRCSC (1) · Michael H Gold, MD (1) · Silvia Codony (1)