2 recruiting, 1 completed. 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Recruiting 2, Completed 1 |
Follow Regn4461: new trials by email Literature Review of Regn4461 trials Research Report on Regn4461
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy Mibavademab, Placebo - Generalized Lipodystrophy | Phase 3 | Recruiting | Regeneron Pharmaceuticals | 28 | 2026-03-13 | 2026-10-23 |
| A Study Evaluating Mibavademab Treatment of Obesity Due to Leptin (LEP) Gene Mutations in Children, Adolescents and Adults Mibavademab - Monogenic Obesity | Phase 3 | Recruiting | Regeneron Pharmaceuticals | 4 | 2026-02-09 | 2026-10-22 |
| A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD) mibavademab - Generalized Lipodystrophy | Phase 3 | Completed | Regeneron Pharmaceuticals | 9 | 2024-12-16 | 2026-07-29 |
Lipodystrophy, Congenital Generalized (2) · Lipodystrophy, Familial Partial (2) · Obesity, Morbid (2) · Diabetes Mellitus (1) · Hypertriglyceridemia (1) · Insulin Resistance (1)
United States (2) · Brazil (1) · France (1) · Germany (1) · Turkey (Türkiye) (1)