5 completed, 3 recruiting, 1 active not recruiting, 1 not yet recruiting. 6 Phase 1, 4 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Recruiting 2 |
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Not yet recruiting 1, Recruiting 1 |
| Not applicable | 1 | Completed 1 |
Follow Psilocybine: new trials by email Literature Review of Psilocybine trials Research Report on Psilocybine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids Biospecimen Collection, Functional Magnetic Resonance Imaging, Interview - Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | Phase 2 | Not yet recruiting | Roswell Park Cancer Institute | 20 | 2026-12-15 | 2026-11-05 |
| Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies Psychotherapy, Psilocybin, Survey Administration - Anxiety, Depression | Phase 2 | Active not recruiting | University of Washington | 16 | 2026-05-19 | 2026-10-29 |
| The RECAP2 Study: Midazolam and Psilocybin Psilocybin, Midazolam, Saline - Psilocybin | Phase 1 | Recruiting | University of Wisconsin, Madison | 60 | 2025-08-07 | 2026-11-06 |
| Investigation to Understand and Optimize Psilocybin Psilocybin, Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Sham taVNS - Depression | Phase 2 | Recruiting | Charles Raison | 141 | 2025-05-13 | 2026-08-10 |
| Consciousness, Psilocybin, and Well-Being Psilocybin, Clonidine, Saline - Healthy, Psychedelic Experiences | Phase 1 | Completed | University of Wisconsin, Madison | 6 | 2023-11-07 | 2025-05-16 |
| Psilocybin-Assisted Therapy for the Treatment of Cancer-Related Anxiety in Patients With Metastatic Cancer Counseling, Psilocybin, Questionnaire Administration - Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm | Phase 1 / Phase 2 | Completed | University of Washington | 55 | 2023-06-27 | 2025-11-05 |
| An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics Psilocybin, Moxifloxacin, Micro-Crystalline Cellulose - QTc Interval, Pharmacokinetics | Phase 1 | Completed | Usona Institute | 60 | 2022-06-22 | 2023-08-15 |
| Pilot RECAP Study in Healthy Volunteers Psilocybin and Midazolam - Psychedelic Experiences, Amnesia | Phase 1 | Completed | University of Wisconsin, Madison | 8 | 2021-05-21 | 2023-05-19 |
| The Neurobiological Effect of 5-HT2AR Modulation Psilocybine, Ketanserin - Basic Science | Phase 1 | Recruiting | Gitte Moos Knudsen | 200 | 2017-03-03 | 2024-12-16 |
| Beyond the Self and Back: Neuropharmacological Mechanisms Underlying the Dissolution of the Self Placebo, Psilocybine - Healthy | Not applicable | Completed | University of Zurich | 140 | 2013-10-01 | 2020-11-04 |
Depression (2) · Neoplasm Metastasis (2) · Amnesia (1) · Anxiety Disorders (1)
University of Wisconsin, Madison (3) · University of Washington (2) · Charles Raison (1) · Gitte Moos Knudsen (1) · Roswell Park Cancer Institute (1) · University of Zurich (1) · Usona Institute (1)
United States (8) · Denmark (1)
Charles Raison, MD (3) · Anthony Back (1) · Anthony Back, MD (1) · Christopher R Nicholas, MD,PHD (1) · Gitte M Knudsen, Professor (1) · William Alexander (1)