5 completed, 2 terminated, 1 withdrawn. 5 Phase 4, 2 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Completed 4, Withdrawn 1 |
| Not applicable | 2 | Terminated 2 |
| Phase 3 | 1 | Completed 1 |
Follow this drug Literature Review of Prostaglandins, Synthetic trials Research Report on Prostaglandins, Synthetic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dose Comparison of Misoprostol for Cervix Ripening Before Operative Hysteroscopy. Misoprostol 200mcg Tab, Misoprostol 800mcg Tab - Cervix; Open | Phase 3 | Completed | Professor Fernando Figueira Integral Medicine Institute | 80 | 2019-11-07 | 2020-10-08 |
| CoQun Study - (COQUN): a Study to Evaluate the Effects of CoQun in Patients Affected by Open-angle Glaucoma Coqun® ophthalmic solution, Placebo ophthalmic solution - Open Angle Glaucoma | Not applicable | Terminated | Mario Negri Institute for Pharmacological Research | 111 | 2017-09-04 | 2024-03-13 |
| SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA) Brinzolamide 1%/brimonidine 0.2% tartrate ophthalmic suspension, Brinz/brim vehicle, Prostaglandin analogue - Open-Angle Glaucoma, Ocular Hypertension | Phase 4 | Completed | Alcon Research | 290 | 2015-08-07 | 2018-11-15 |
| The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients. Prostaglandin Analog, Timolol - Thyroid Eye Disease, Ocular Hypertension | Phase 4 | Withdrawn | Stanford University | 2014-06-01 | 2018-05-15 | |
| Primary Glaucoma Treatment Trial in Kenya and South Africa - SLT vs. Medication Prostaglandin analogue, Selective laser trabeculoplasy, laser - Glaucoma | Not applicable | Terminated | University College, London | 15 | 2014-02-01 | 2019-05-02 |
| Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue Brinzolamide 1%/brimonidine 0.2% ophthalmic suspension, Vehicle, Prostaglandin analogue - Ocular Hypertension, Open Angle Glaucoma | Phase 4 | Completed | Alcon Research | 282 | 2013-10-01 | 2015-07-28 |
| The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle Glaucoma topical prostaglandin analogs - Glaucoma, Open-Angle | Phase 4 | Completed | Maisonneuve-Rosemont Hospital | 35 | 2013-05-06 | 2021-02-26 |
| How Similar Are Changes to the Surface of the Eye When Two Different Glaucoma Eye Drops Are Used? Xalatan, Travatan Z - Glaucoma | Phase 4 | Completed | Wills Eye | 58 | 2008-11-01 | 2018-07-12 |
Glaucoma (4) · Glaucoma, Open-Angle (4) · Ocular Hypertension (3) · Graves Disease (1) · Graves Ophthalmopathy (1) · Uterine Cervical Incompetence (1)
Alcon Research (2) · Maisonneuve-Rosemont Hospital (1) · Mario Negri Institute for Pharmacological Research (1) · Professor Fernando Figueira Integral Medicine Institute (1) · Stanford University (1) · University College, London (1) · Wills Eye (1)
United States (3) · Brazil (1) · Canada (1) · Italy (1) · Kenya (1)
Andrea L. Kossler, M.D. (1) · Ian Murdoch, MD FRCOphth (1) · Leslie J Katz, MD (1) · Luciano Quaranta, MD PhD (1) · Paul Harasymowycz, Dr (1) · Steve Burmaster, PhD (1)
PMID 27162226, PMID 28617732, PMID 31301054, PMID 34695232
2015 (1)