6 unknown, 4 completed. 3 Phase 3, 1 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 3 | Completed 2, Unknown 1 |
| Not applicable | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Unknown 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Propylthiouracil: new trials by email Literature Review of Propylthiouracil trials Research Report on Propylthiouracil
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Networked Drug REpurposing for Mechanism-based neuroPrOtection in Acute Ischaemic STROKE Riociguat, Propylthiouracil, Perphenazine - Ischemic Stroke, Acute | Phase 2 | Unknown | Maastricht University | 28 | 2022-09-05 | 2023-10-19 |
| Possible Effects of Propylthiouracil, Riociguat and Perphenazine on Circulation of Healthy Volunteers Propylthiouracil, Riociguat, Perphenazine - Drug Drug Interaction, Safety Issues | Phase 1 | Completed | Maastricht University | 8 | 2021-03-18 | 2022-04-04 |
| Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis Propylthiouracil, Methimazole - Hyperthyroidism, Graves Disease | Phase 3 | Completed | Universitas Indonesia | 36 | 2019-01-01 | 2021-11-12 |
| The Oral Microbiota is Associated With Autoimmune Thyroiditis Methimazole Pill, Propylthiouracil Pill - Microbiota | Unknown | First Affiliated Hospital of Harbin Medical University | 120 | 2017-12-23 | 2018-02-27 | |
| Intestinal Microbiota and Treatment of GD Methimazole Pill, Propylthiouracil Pill - Microbiota | Unknown | First Affiliated Hospital of Harbin Medical University | 90 | 2017-12-23 | 2018-02-14 | |
| Total Thyroidectomy Versus Thionamides in Patients With Moderate-to-Severe Graves' Ophthalmopathy Antithyroid Drug, Total thyroidectomy - Graves Disease, Graves Ophthalmopathy | Phase 3 | Unknown | Medical University of Vienna | 60 | 2017-03-01 | 2017-02-28 |
| Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism thionamide treatment for 3 months - Hyperthyroidism | Unknown | Hu Hao | 240 | 2016-07-01 | 2016-07-06 | |
| The Effect of Early Total Thyroidectomy in the Course of Graves' Orbitopathy Total Thyroidectomy, Propylthiouracil - Graves' Ophthalmopathy | Phase 4 | Unknown | Ankara University | 40 | 2009-01-01 | 2010-01-26 |
| Thyroid Disease in Pregnancy: Case Finding Versus Universal Screening Levothyroxine, Propylthiouracile - Thyroid Disease, Pregnancy | Not applicable | Completed | Ospedale V. Fazzi | 4657 | 2005-03-01 | 2011-09-27 |
| Antithyroid Drug Treatment of Thyrotoxicosis in Young People Block and Replace, Dose Titration, carbimazole - Paediatric Thyrotoxicosis | Phase 3 | Completed | Newcastle-upon-Tyne Hospitals NHS Trust | 81 | 2004-07-01 | 2016-09-21 |
Graves Disease (4) · Graves Ophthalmopathy (2) · Hyperthyroidism (2) · Atherosclerosis (1) · Bites and Stings (1) · Hashimoto Disease (1) · Insulin Resistance (1) · Ischemic Stroke (1) · Thyroid Diseases (1) · Thyrotoxicosis (1)
First Affiliated Hospital of Harbin Medical University (2) · Maastricht University (2) · Ankara University (1) · Hu Hao (1) · Medical University of Vienna (1) · Newcastle-upon-Tyne Hospitals NHS Trust (1) · Ospedale V. Fazzi (1) · Universitas Indonesia (1)
China (3) · Germany (2) · Austria (1) · Indonesia (1) · Italy (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Yunwei Wei (2) · Cai Ruonan, MD (1) · Gao Zhaohua, MD (1) · Guido Dorner, MD (1) · Hu Hao, MD (1) · Philipp Riss, MD (1) · Roberto Negro, Dr (1) · Tim Cheetham (1) · Walter E. Haefeli, Prof. Dr. (1) · Wang Zhaoling, BD (1) · Yin Wenwen, MD (1) · Zhou Tingting, MD (1)
PMID 21190974, PMID 21411559, PMID 24262987, PMID 39355401, PMID 40371623
2015 (1), 2019 (1)