72 completed, 31 unknown, 13 terminated, 3 withdrawn. 23 Phase 2, 14 Phase 1, 2 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 23 | Completed 16, Terminated 4, Unknown 3 |
| Phase 1 | 14 | Completed 9, Terminated 3, Unknown 1, Withdrawn 1 |
| Not applicable | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Completed 2 |
Follow polymorphism analysis: new trials by email Literature Review of polymorphism analysis trials Research Report on polymorphism analysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of ABCB1,SLC22A16 Drug Transporter Genes and Doxorubicin and Cyclophosphamide Toxicity in Brest Cancer Patient polymorphism analysis, Doxorubicin-Cyclophosphamide regimen - Breast Cancer Patients | Unknown | Damanhour University | 100 | 2020-12-01 | 2020-12-04 | |
| Study of CYP2C19 and ALDH3A1 Polymorphisms in Breast Cancer Patients polymorphism analysis, Doxorubicin-Cyclophosphamide regimen - Breast Cancer Patients | Unknown | Damanhour University | 100 | 2020-10-15 | 2020-10-09 | |
| Oxaliplatin - Induced Peripheral Neuropathy in Patients With Gastrointestinal Tract Cancer polymorphism analysis - Gastrointestinal Tract Cancer, Peripheral Neuropathy | Unknown | Ain Shams University | 80 | 2014-11-01 | 2023-11-28 | |
| Biomarkers in DNA Samples From Patients With High-Risk Acute Lymphoblastic Leukemia DNA analysis, genetic linkage analysis, microarray analysis - Leukemia | Completed | Children's Oncology Group | 350 | 2013-02-01 | 2016-07-11 | |
| Collecting and Studying Tissue Samples From Patients With HIV-Associated Malignancies DNA analysis, RNA analysis, gene expression analysis - Lung Cancer, Lymphoma | Terminated | AIDS Malignancy Consortium | 114 | 2013-01-02 | 2023-03-16 | |
| Studying Biomarkers in Samples From Patients With Recurrent or Metastatic Head and Neck Cancer Treated on E1302 Trial mutation analysis, polymerase chain reaction, polymorphism analysis - Head and Neck Cancer | Completed | Eastern Cooperative Oncology Group | 183 | 2012-06-01 | 2017-05-17 | |
| Studying Genes Using Cord Blood and Placenta Samples From Relatively Healthy Newborns and Samples From Younger Patients With Wilms Tumor DNA methylation analysis, RNA analysis, allele-specific oligonucleotide real-time quantitative polymerase chain reaction - Kidney Cancer | Completed | Children's Oncology Group | 40 | 2012-04-01 | 2016-05-18 | |
| Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer DNA analysis, DNA methylation analysis, RNA analysis - Lung Cancer | Completed | Alliance for Clinical Trials in Oncology | 248 | 2012-03-01 | 2017-06-27 | |
| Biomarkers in Predicting Response to Rituximab Treatment in Samples From Patients With Indolent Follicular Lymphoma rituximab, DNA analysis, gene expression analysis - Lymphoma | Completed | ECOG-ACRIN Cancer Research Group | 259 | 2012-02-06 | 2017-05-17 | |
| Studying Genes in Samples From Younger Patients With Adrenocortical Tumor DNA methylation analysis, RNA analysis, gene expression analysis - Adrenocortical Carcinoma | Completed | Children's Oncology Group | 10 | 2012-02-01 | 2016-05-18 | |
| Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin Lymphoma brentuximab vedotin, doxorubicin hydrochloride, vinblastine - Adult Lymphocyte Depletion Hodgkin Lymphoma, Adult Lymphocyte Predominant Hodgkin Lymphoma | Phase 2 | Completed | Northwestern University | 49 | 2011-11-01 | 2026-05-22 |
| Studying Biomarkers in Samples From Younger Patients With Malignant Germ Cell Tumor Progression DNA methylation analysis, RNA analysis, mutation analysis - Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor | Completed | Children's Oncology Group | 90 | 2011-10-01 | 2016-05-18 | |
| Study of Blood and Tissue Samples in Children With Newly Diagnosed Acute Lymphoblastic Leukemia gene expression analysis, mutation analysis, polymorphism analysis - Leukemia, Lymphoma | Unknown | European Organisation for Research and Treatment of Cancer - EORTC | 1200 | 2011-06-01 | 2017-07-28 | |
| Relationship Between Vitamin D Biomarkers and Survival in Blood Samples From Patients With Advanced Pancreatic Cancer polymorphism analysis, immunologic technique, laboratory biomarker analysis - Pancreatic Cancer | Completed | Alliance for Clinical Trials in Oncology | 265 | 2011-06-01 | 2016-06-29 | |
| Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing Cancer DNA analysis, cytogenetic analysis, gene expression analysis - Brain and Central Nervous System Tumors, Hereditary Wilms Tumor | Completed | Children's Oncology Group | 31 | 2011-05-01 | 2016-07-11 | |
| Biomarkers in Tissue Samples From Patients With Breast Cancer Treated With Bevacizumab DNA analysis, gene expression analysis, polymorphism analysis - Breast Cancer | Completed | ECOG-ACRIN Cancer Research Group | 363 | 2011-04-05 | 2017-05-17 | |
| Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma everolimus, lenalidomide, laboratory biomarker analysis - Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma | Phase 1 / Phase 2 | Completed | Mayo Clinic | 58 | 2011-01-10 | 2020-10-22 |
| Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia alemtuzumab, rituximab, PGG beta-glucan - B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia | Phase 1 / Phase 2 | Completed | Mayo Clinic | 22 | 2011-01-01 | 2020-06-23 |
| Study of Changes in Estrogen Levels and Grip Strength in Postmenopausal Women Who Have Received 4 to 6 Years of Hormone Therapy for Breast Cancer and Are Currently Receiving Letrozole on Clinical Trial IBCSG-35-07 polymorphism analysis, laboratory biomarker analysis, quality-of-life assessment - Breast Cancer | Completed | ETOP IBCSG Partners Foundation | 104 | 2011-01-01 | 2026-10-06 | |
| Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the Head and Neck erlotinib hydrochloride, intensity-modulated radiation therapy, pharmacogenomic studies - Stage III Squamous Cell Carcinoma of the Hypopharynx, Stage III Squamous Cell Carcinoma of the Larynx | Phase 2 | Terminated | Case Comprehensive Cancer Center | 2 | 2011-01-01 | 2020-05-12 |
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Breast Neoplasms (24) · Leukemia (13) · Lymphoma (13) · Lymphoma, Follicular (12) · Colonic Neoplasms (10) · Prostatic Neoplasms (10) · Rectal Neoplasms (10) · Carcinoma, Non-Small-Cell Lung (9) · Lymphoma, Large B-Cell, Diffuse (9) · Colorectal Neoplasms (8) · Lung Neoplasms (8) · Congenital Abnormalities (7) · Hodgkin Disease (7) · Leukemia, Lymphocytic, Chronic, B-Cell (7) · Lymphoma, B-Cell, Marginal Zone (7)
Children's Oncology Group (10) · ECOG-ACRIN Cancer Research Group (9) · Cancer Research UK (8) · SWOG Cancer Research Network (8) · Alliance for Clinical Trials in Oncology (7) · Case Comprehensive Cancer Center (6) · Eastern Cooperative Oncology Group (6) · Mayo Clinic (4) · University of Nebraska (4) · Vanderbilt-Ingram Cancer Center (4) · Children's Cancer and Leukaemia Group (3) · Fred Hutchinson Cancer Center (3) · Damanhour University (2) · Gynecologic Oncology Group (2) · NSABP Foundation Inc (2)
United States (50) · United Kingdom (19) · France (4) · Egypt (3) · Ireland (3) · Australia (2) · Belgium (2) · China (2) · Canada (1) · Germany (1) · Italy (1) · Netherlands (1) · New Zealand (1) · Portugal (1) · Puerto Rico (1)
Paul Pharoah, MD (7) · Jill Kolesar, PharmD (3) · Angela Cox, PhD (2) · Brad S. Kahl, MD (2) · Bryan P. Schneider, MD (2) · Christine B. Ambrosone, PhD (2) · Elinor Sawyer, MD (2) · Gareth Veal (2) · Heinz-Josef Lenz, MD (2) · James N. Ingle, MD (2) · Madan Jagasia, MD (2) · Rebecca Roylance, MD (2) · Alan Venook, MD (1) · Allison C. Rosenthal, D.O. (1)
PMID 15662127, PMID 18483359, PMID 20035238, PMID 20309628, PMID 21169260, PMID 21880792, PMID 22271896, PMID 23273589, PMID 23764181, PMID 24099865, PMID 24100924, PMID 24383844, PMID 24758527, PMID 24827132, PMID 25114718, PMID 25135992, PMID 25361995, PMID 25527568, PMID 25621498, PMID 26163096, PMID 26242208, PMID 28624696, PMID 28830573, PMID 29724294, PMID 29913374, PMID 30179569, PMID 30402678, PMID 30633128, PMID 31178155, PMID 33555272, PMID 38195521
P30CA068485 (6), U10CA032102 (5), P30CA036727 (3), P01HL036444 (2), U10CA031946 (2), K23HL084054 (1), P01CA018029 (1), P01CA078902 (1), P30CA006973 (1), P30CA012197 (1), P30CA015083 (1), P30CA022453 (1), P30CA033572 (1), P30CA043703 (1), P30CA082709 (1)