10 terminated. 10 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Terminated 10 |
| Phase 2 | 2 | Terminated 2 |
Follow plerixafor: new trials by email Literature Review of plerixafor trials Research Report on plerixafor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer 18F-FHBG, Aldesleukin, Busulfan - HLA-A*0201 Positive Cells Present, Locally Advanced Malignant Neoplasm | Phase 1 | Terminated | Jonsson Comprehensive Cancer Center | 5 | 2017-07-26 | 2023-11-01 |
| To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas Plerixafor - Pancreas Cancer | Phase 1 | Terminated | Weill Medical College of Cornell University | 2 | 2017-07-25 | 2020-03-02 |
| Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation Fludarabine, Fractionated total body irradiation, Busulfan - Acute Myeloid Leukemia, Myelodysplastic Syndrome | Phase 1 | Terminated | Washington University School of Medicine | 5 | 2016-06-27 | 2020-10-20 |
| Pilot Study of Lymphoid Tumor Microenvironmental Dysruption Prior to Autologous Stem Cell Transplantation Plerixafor - Chronic Lymphocytic Leukemia, Lymphoma | Phase 1 | Terminated | Tufts Medical Center | 7 | 2013-07-01 | 2017-05-09 |
| AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy Resistant Pediatric Acute Leukemia AMD3100 - Pediatric Acute Myeloblastic Leukemia, Relapsed, Pediatric Acute Lymphoblastic Leukemia, Relapsed | Phase 1 | Terminated | Emory University | 1 | 2012-06-01 | 2014-04-07 |
| Gene Therapy for Fanconi Anemia Bone Marrow Aspiration, Filgrastim, Genetically Engineered Hematopoietic Stem Progenitor Cells - Fanconi Anemia | Phase 1 | Terminated | Fred Hutchinson Cancer Center | 3 | 2012-02-22 | 2024-05-17 |
| Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma Plerixafor, Bevacizumab, Surgery - High Grade Glioma: Glioblastoma (GBM), High Grade Glioma: Gliosarcoma | Phase 1 | Terminated | Patrick Y. Wen, MD | 26 | 2011-12-01 | 2017-11-17 |
| Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML) Plerixafor, Clofarabine - Acute Myelogenous Leukemia | Phase 1 / Phase 2 | Terminated | M.D. Anderson Cancer Center | 22 | 2010-08-01 | 2019-08-28 |
| IV Plerixafor With Mitoxantrone Etoposide and Cytarabine for Acute Myeloid Leukemia (AML) Plerixafor, Mitoxantrone, Etoposide - Leukemia, Myeloid, Acute | Phase 1 | Terminated | Washington University School of Medicine | 6 | 2010-05-01 | 2015-01-26 |
| O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Carmustine - Glioblastoma, Gliosarcoma | Phase 1 / Phase 2 | Terminated | Fred Hutchinson Cancer Center | 12 | 2009-02-25 | 2022-05-18 |
Leukemia, Myeloid, Acute (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (2) · Astrocytoma (1) · Fanconi Anemia (1) · Glioblastoma (1) · Gliosarcoma (1) · Leukemia (1) · Leukemia, Lymphocytic, Chronic, B-Cell (1) · Lymphoma (1) · Multiple Myeloma (1) · Myelodysplastic Syndromes (1) · Oligodendroglioma (1) · Pancreatic Neoplasms (1) · Recurrence (1) · Sarcoma (1)
Fred Hutchinson Cancer Center (2) · Washington University School of Medicine (2) · Emory University (1) · Jonsson Comprehensive Cancer Center (1) · M.D. Anderson Cancer Center (1) · Patrick Y. Wen, MD (1) · Tufts Medical Center (1) · Weill Medical College of Cornell University (1)
United States (10) · United Kingdom (1)
Hans-Peter Kiem (2) · Andreas K Klein, MD (1) · Duncan Jodrell, MD (1) · Elizabeta Popa, MD (1) · Geoffrey Uy, M.D. (1) · Jan A. Burger, MD (1) · Kuang-Yueh Chiang, MD, PhD (1) · Mark Schroeder, M.D. (1) · Patrick Y. Wen, MD (1) · Theodore Scott Nowicki, M.D. (1)