7 completed, 2 terminated, 1 unknown. 3 Phase 2, 3 Phase 4, 2 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Terminated 1 |
| Phase 4 | 3 | Completed 3 |
| Not applicable | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Phenergan: new trials by email Literature Review of Phenergan trials Research Report on Phenergan
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Pruritus With Intramuscular Promethazine Promethazine, Placebo - Pruritus, Pregnancy Related | Phase 4 | Completed | University of Florida | 72 | 2021-08-09 | 2025-05-04 |
| Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease Fluconazole, Vancomycin, Neomycin - Crohn's Disease | Phase 2 | Completed | University of Pennsylvania | 8 | 2016-08-01 | 2024-02-06 |
| Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV) Electrical Stimulation, Zofran, Dexamethasone - Post-Operative Nausea and Vomiting, Breast Cancer | Not applicable | Completed | M.D. Anderson Cancer Center | 188 | 2016-03-01 | 2025-12-05 |
| A Four-Period, Four-Treatment, Four-Way Relative Bioavailability Study of CL-108 Under Fed and Fasted Conditions CL-108, Vicoprofen, Ultracet - Healthy | Phase 1 | Completed | Charleston Laboratories, Inc | 20 | 2014-11-01 | 2017-05-02 |
| Study of Promethazine for Treatment of Diabetic Gastroparesis Promethazine, Sugar pill - Diabetic Gastroparesis | Phase 2 | Terminated | Dartmouth-Hitchcock Medical Center | 3 | 2014-07-01 | 2018-08-07 |
| Countermeasures to Reduce Sensorimotor Impairment and Space Motion Sickness Resulting From Altered Gravity Levels Promethazine, Hyper gravity training, Placebo - Vestibular | Phase 4 | Completed | Faisal_Karmali@MEEI.HARVARD.EDU | 30 | 2014-06-01 | 2018-01-08 |
| Sunitinib or Cediranib for Alveolar Soft Part Sarcoma Cediranib, Sunitinib, Prochlorperazine - Sarcoma, Alveolar Soft Part | Phase 2 | Completed | National Cancer Institute (NCI) | 34 | 2011-07-18 | 2026-02-02 |
| Effectiveness of Triple Therapy With Palonosetron for PON Prophylaxis Palonosetron 0.075 mg IV, Dexamethasone 10 mg IV, Promethazine 25 mg IV - Postoperative Nausea and Vomiting | Phase 4 | Completed | Ohio State University | 40 | 2009-10-01 | 2017-05-05 |
| Effects of Oral Midazolam in Comparison Promethazine With Nitrous Oxide for Uncooperative Children Promethazine - Conscious Sedation | Phase 3 | Unknown | Shahid Beheshti University | 20 | 2009-06-01 | 2010-05-07 |
| Prevention of Narcotic-Induced Nausea Saline, Phenergan - Nausea | Not applicable | Terminated | Christiana Care Health Services | 25 | 2007-02-01 | 2014-03-13 |
Nausea (2) · Postoperative Nausea and Vomiting (2) · Vomiting (2) · Breast Neoplasms (1) · Crohn Disease (1) · Pruritus (1) · Sarcoma, Alveolar Soft Part (1)
Charleston Laboratories, Inc (1) · Christiana Care Health Services (1) · Dartmouth-Hitchcock Medical Center (1) · Faisal_Karmali@MEEI.HARVARD.EDU (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · Ohio State University (1) · Shahid Beheshti University (1) · University of Florida (1) · University of Pennsylvania (1)
United States (7) · Iran (1)
Adam Wendling, MD (1) · Alberto A Uribe, M.D. (1) · Alice P Chen, M.D. (1) · Alicia M. Kowalski, MD (1) · Brian E. Lacy, MD (1) · Faisal Karmali, Ph.D. (1) · James D Lewis, MD, MSCE (1) · Lindsey Albenberg, DO (1) · Michael Perraut, MD (1) · Sedighe Mozaffar (1)
PMID 10078396, PMID 10475299, PMID 10485781, PMID 10624646, PMID 10730546, PMID 10910848, PMID 11050519, PMID 11454483, PMID 12818945, PMID 14504060, PMID 14620731, PMID 15064259, PMID 15120791, PMID 15139789, PMID 16528908, PMID 16597655, PMID 16766588, PMID 16934536, PMID 18633021, PMID 18633022, PMID 18633025, PMID 25971957, PMID 26870733, PMID 27521593, PMID 28439720, PMID 36302173, PMID 7848959