5 completed, 2 not yet recruiting, 2 recruiting, 2 unknown. 4 Phase 4, 3 Phase 3, 2 Not applicable, 2 Phase 2, 1 Early Phase 1.
Follow PEG 3350: new trials by email Literature Review of PEG 3350 trials Research Report on PEG 3350
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Senna vs. Polyethylene Glycol 3350 for the Treatment of Retentive Encopresis in Children PEG 3350, Senna - Encopresis With Constipation and Overflow Incontinence | Early Phase 1 | Not yet recruiting | Shaare Zedek Medical Center | 80 | 2026-07-01 | 2026-06-18 |
| A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation Actazin chewable tablet, PEG 3350, Chewable Tablet - Constipation - Functional, Constipation | Phase 2 / Phase 3 | Not yet recruiting | Hamilton Health Sciences Corporation | 60 | 2025-06-01 | 2025-03-19 |
| PEG3350 vs Senna After Urogyn Surgery Senna, Polyethylene glycol 3350 - Obstructive Defecation Syndrome, Postoperative Constipation | Phase 4 | Recruiting | St. Joseph's Health, New York | 254 | 2025-04-23 | 2025-05-28 |
| Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen PEG 3350, PEG-3350 with electrolytes, Glycerin - Constipation | Phase 4 | Recruiting | Indiana University | 65 | 2023-06-08 | 2026-08-18 |
| A Phase 3 Trial in Bowel Preparation for Colonoscopy CTP0301-A, CTP0301-B, Cool prep - Bowel Preparation | Phase 3 | Completed | Taejoon Pharmaceutical Co., Ltd. | 137 | 2023-01-30 | 2024-02-28 |
| Polyethylene Glycol Safety in Children PEG 3350 - Polyethylene Glycols, Children, Only | Completed | Children's Hospital of Philadelphia | 158 | 2022-09-30 | 2025-11-04 | |
| Post-Operative Constipation Following Total Knee Arthroplasty Propylene Glycol, Docusate Sodium - Constipation | Phase 2 | Completed | The Cleveland Clinic | 154 | 2020-02-21 | 2022-01-19 |
| Efficacy and Safety of PEG 3350 for Treatment of Chronic Constipation PEG 3350, Lactulose - Constipation - Functional | Phase 3 | Unknown | Fakultas Kedokteran Universitas Indonesia | 184 | 2019-12-07 | 2020-10-20 |
| Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity prucalopride, PEG 3350 - Chronic Constipation | Phase 4 | Completed | Shire | 13 | 2013-02-27 | 2021-07-02 |
| MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery MiraLax, Placebo, Rescue Laxative - Post Procedural Constipation | Not applicable | Completed | Duke University | 131 | 2012-09-01 | 2017-02-15 |
| Clostridial Infection and Oral Lavage -Improving Treatment Before Illness Becomes Severe Nu-Lytely - Clostridium Difficile Colitis | Phase 4 | Unknown | Ascension Health | 200 | 2012-06-01 | 2012-08-17 |
| Comparison Trial of Enema vs. PEG 3350 for Constipation PEG 3350, milk and molasses enema - Constipation | Not applicable | Terminated | Children's Mercy Hospital Kansas City | 80 | 2006-12-01 | 2020-11-02 |
Constipation (5) · Enterocolitis, Pseudomembranous (1) · Fecal Impaction (1)
Ascension Health (1) · Children's Hospital of Philadelphia (1) · Children's Mercy Hospital Kansas City (1) · Duke University (1) · Fakultas Kedokteran Universitas Indonesia (1) · Hamilton Health Sciences Corporation (1) · Indiana University (1) · Shaare Zedek Medical Center (1) · Shire (1) · St. Joseph's Health, New York (1) · Taejoon Pharmaceutical Co., Ltd. (1) · The Cleveland Clinic (1)
United States (8) · Belgium (1) · Canada (1) · Indonesia (1) · Israel (1) · South Korea (1) · United Kingdom (1)
Anthony G Visco, MD (1) · Elyanne Ratcliffe, MD (1) · Kate Hawa, DO (1) · Kathleen Gonzalez, RN, MSN (1) · Keila S Muniz, MD (1) · Mark B. Vance, DO (1) · Melissa K Miller, MD (1) · Mohamed M Eltorki, MBChB, MSc (1) · Murdani Abdulah (1) · Robert O Heuckeroth, MD, PhD (1)