2 not yet recruiting, 2 recruiting, 1 unknown. 2 Phase 3, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Not yet recruiting 1, Recruiting 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow this drug Literature Review of PCSK9 Inhibitors trials Research Report on PCSK9 Inhibitors
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PCSK9 Inhibitors in the Treatment of Calcific Aortic Stenosis Treatment with PCSK9 inhibitors, Treatment without PCSK9 inhibitors - Aortic Stenosis, Calcific | Phase 3 | Not yet recruiting | Beijing Anzhen Hospital | 160 | 2026-04-01 | 2026-04-02 |
| COAST Study - Cholesterol Optimization After Stroke low-fat diet, supplements, statins, ezetimibe, bempedoic acid, PCSK9 inhibitors, fibrates, or other lipid-lowering agents - Stroke (CVA) or Transient Ischemic Attack, Cerebral Hemorrhage | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 500 | 2026-01-01 | 2025-12-01 | |
| Further Lipid-Lowering With PCSK9 Inhibitors for Cardiovascular Outcomes in High-Risk Coronary Plaques Assessed by CT Angiography PCSK9 inhibitors and background lipid-modifying therapy, Standard lipid-modifying therapy - Coronary Artery Disease, CT Angiography | Not applicable | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 3596 | 2025-04-22 | 2026-02-06 |
| Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients Lipid-lowering therapy combination with PCSK9 inhibitors, bempedoic acid and ezetimibe, Lipid-lowering therapy combination with PCSK9 inhibitors and ezetimibe - Dyslipidemias, Statin Adverse Reaction | Phase 4 | Unknown | University of Salerno | 130 | 2024-05-01 | 2024-04-24 |
| Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis PCSK9 inhibitors and statins with or without ezetimibe, Statins with or without ezetimibe - Aortic Stenosis | Phase 3 | Recruiting | Beijing Anzhen Hospital | 160 | 2024-03-22 | 2024-05-09 |
Aortic Valve, Calcification of (2) · Aortic Valve Stenosis (1) · Cardiovascular Diseases (1) · Cerebral Hemorrhage (1) · Coronary Artery Disease (1) · Dyslipidemias (1) · Ischemic Attack, Transient (1) · Lipid Metabolism Disorders (1) · Stroke (1)
Beijing Anzhen Hospital (2) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · University of Salerno (1)
China (3) · South Korea (1)
Zhijian Wang (2) · Bon-Kwon Koo (1) · Xiaoteng Ma (1) · Xinyang Hu (1)