6 completed, 2 withdrawn. 8 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 6, Withdrawn 2 |
| Phase 3 | 1 | Completed 1 |
Follow Norethindrone Acetate: new trials by email Literature Review of Norethindrone Acetate trials Research Report on Norethindrone Acetate
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| IUD and Norethindrone Acetate for Treatment of Endometriosis norethindrone acetate (NETA), Placebo - Endometriosis | Phase 2 | Withdrawn | Boston Children's Hospital | 2026-01-01 | 2025-03-21 | |
| Phenotyping of Idiopathic Pelvic Pain With Real-time Uterine Imaging and Relugolix-Combination Therapy Treatment Relugolix (40 mg) /estradiol (1 mg)/norethisterone acetate (0.5 mg) oral tablet - Pelvic Pain | Phase 2 | Withdrawn | Endeavor Health | 2024-06-01 | 2025-08-28 | |
| Dopamine Receptor Agonist Therapy for Pain Relief in Women Suffering From Endometriosis: A Pilot Study Cabergoline, Norethindrone acetate - Endometriosis | Phase 2 | Completed | Boston Children's Hospital | 10 | 2016-05-01 | 2020-02-05 |
| Safety and Efficacy in Premenopausal Women With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF) Elagolix placebo, Elagolix, 0.5 mg estradiol / 0.1 mg norethindrone acetate - Heavy Uterine Bleeding, Uterine Fibroids | Phase 2 | Completed | AbbVie | 571 | 2013-04-08 | 2020-07-21 |
| Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids Elagolix, Placebo, Estradiol/Norethindrone acetate (E2/NETA) - Heavy Uterine Bleeding, Uterine Fibroids | Phase 2 | Completed | AbbVie (prior sponsor, Abbott) | 271 | 2011-09-08 | 2021-07-13 |
| The Effect of Hormonal Add-Back Therapy in Adolescents Treated With a GnRH Agonist for Endometriosis: A Randomized Trial Norethindrone acetate + estrogens, norethindrone acetate + placebo - Endometriosis | Phase 2 | Completed | Boston Children's Hospital | 53 | 2007-08-01 | 2015-03-30 |
| Genistein and Endometrial Hyperplasia Genivis, Norethisterone Acetate, placebo - Endometrial Hyperplasia | Phase 2 | Completed | University of Messina | 59 | 2007-01-01 | 2008-12-19 |
| Efficiency of Gonadotropin-releasing Hormone (GnRH) Agonist in Preventing Chemotherapy Induced Ovarian Failure Triptorelin, Norethisterone acetate - Fertility Preservation, Alkylating Agents | Phase 2 / Phase 3 | Completed | Erasme University Hospital | 118 | 2002-07-01 | 2015-10-30 |
Endometriosis (3) · Leiomyoma (2) · Menorrhagia (2) · Endometrial Hyperplasia (1) · Lymphoma (1) · Metrorrhagia (1) · Pelvic Pain (1)
Boston Children's Hospital (3) · AbbVie (1) · AbbVie (prior sponsor, Abbott) (1) · Endeavor Health (1) · Erasme University Hospital (1) · University of Messina (1)
United States (4) · Italy (2) · Belgium (1) · France (1)
Amy D DiVasta, MD, MMSc (1) · Amy DiVasta (1) · Charlotte Owens, MD (1) · Rosario D'Anna, prof. (1) · Yvon Englert, MD, PhD (1)
PMID 12466350, PMID 23129737, PMID 26181088, PMID 27733082, PMID 30303923, PMID 30454733, PMID 34934987