3 completed, 1 unknown. 4 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow Nifurtimox: new trials by email Literature Review of Nifurtimox trials Research Report on Nifurtimox
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| New Therapies and Biomarkers for Chagas Infection Benznidazole, Nifurtimox - Trypanosoma Cruzi Infection, Chagas Disease | Phase 2 | Completed | University of Texas, El Paso | 450 | 2019-12-18 | 2024-07-17 |
| CHICAMOCHA 3 - Equivalence of Usual Interventions for Trypanosomiasis (EQUITY) Nifurtimox, Benznidazole, Placebo - Chagas Disease | Phase 2 / Phase 3 | Unknown | Universidad Autónoma de Bucaramanga | 500 | 2015-08-01 | 2017-07-21 |
| Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2 Fexinidazole, Nifurtimox, Eflornithine - Human African Trypanosomiasis (HAT), Sleeping Sickness | Phase 2 / Phase 3 | Completed | Drugs for Neglected Diseases | 394 | 2012-10-01 | 2018-02-20 |
| Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma Nifurtimox, Cyclophosphamide, Topotecan - Neuroblastoma, Medulloblastoma | Phase 2 | Completed | Giselle Sholler | 112 | 2008-01-14 | 2024-08-06 |
Chagas Disease (2) · Medulloblastoma (1) · Neuroblastoma (1) · Parasitic Diseases (1) · Trypanosomiasis, African (1)
Drugs for Neglected Diseases (1) · Giselle Sholler (1) · Universidad Autónoma de Bucaramanga (1) · University of Texas, El Paso (1)
Bolivia (1) · Central African Republic (1) · Colombia (1) · Democratic Republic of the Congo (1) · Republic of the Congo (1) · United States (1)
Faustino Torrico, M.D., Ph.D (1) · Giselle Sholler, MD (1) · Igor C Almeida, D.Sc. (1) · Joaquim Gascon, M.D., Ph.D (1) · Juan C Villar, MD, PhD (1)
PMID 29113731, PMID 31307503, PMID 34972765, PMID 42772313
U01AI129783 (1)