5 completed, 2 recruiting, 1 unknown. 3 Phase 2, 2 Phase 3, 2 Phase 4, 1 Early Phase 1, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 1 | 1 | Completed 1 |
Follow Naltrexone Pill: new trials by email Literature Review of Naltrexone Pill trials Research Report on Naltrexone Pill
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emergency Department-Initiated Medications for Alcohol Use Disorder Naltrexone Pill, Naltrexone Injection, Brief Negotiation Interview - Alcohol Use Disorder | Phase 3 | Recruiting | Yale University | 240 | 2024-08-17 | 2026-07-21 |
| Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2) Ketamine, Naltrexone Pill, Placebo pill - Obsessive-Compulsive Disorder | Phase 2 | Recruiting | Stanford University | 150 | 2024-02-24 | 2026-04-24 |
| Bridging ED to Outpatient AUD Therapy With Naltrexone Naltrexone Pill - Alcohol Use Disorder | Phase 4 | Unknown | Albert Einstein Healthcare Network | 20 | 2022-03-01 | 2022-02-08 |
| Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcohol Use Disorder Oxytocin nasal spray, Naltrexone Pill, Placebo - Alcohol Use Disorder, Alcoholism | Phase 2 / Phase 3 | Completed | Central Institute of Mental Health, Mannheim | 62 | 2021-12-02 | 2024-03-29 |
| Understanding How Opioids Affect the Experiential and Neural Signatures of Social Experiences Naltrexone Hydrochloride, Placebo - Naltrexone, Placebo | Early Phase 1 | Completed | San Diego State University | 217 | 2021-11-16 | 2026-09-10 |
| Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude Naltrexone Pill, Placebo - Altitude, Sleep Apnea, Central | Phase 4 | Completed | VA Loma Linda Health Care System | 16 | 2021-08-08 | 2023-04-26 |
| Fibromyalgia and Naltrexone: The FINAL Study Naltrexone Pill, Placebo oral tablet - Fibromyalgia | Phase 2 | Completed | Odense University Hospital | 99 | 2021-01-06 | 2022-12-29 |
| Efficacy of Low Dose Naltrexone in Psoriasis Naltrexone Pill - Psoriasis | Phase 1 | Completed | Jinnah Postgraduate Medical Centre | 42 | 2019-01-01 | 2020-01-31 |
Alcoholism (3) · Emergencies (1) · Fibromyalgia (1) · Obsessive-Compulsive Disorder (1) · Psoriasis (1) · Sleep Apnea, Central (1)
Albert Einstein Healthcare Network (1) · Central Institute of Mental Health, Mannheim (1) · Jinnah Postgraduate Medical Centre (1) · Odense University Hospital (1) · San Diego State University (1) · Stanford University (1) · VA Loma Linda Health Care System (1) · Yale University (1)
United States (5) · Denmark (1) · Germany (1) · Pakistan (1)
David Hui, MD (1) · James D Anholm, MD (1) · Karin D Bruun, Consultant (1) · Kathryn Hawk, MD, MHS (1) · Patrick Bach, MD (1) · Rabia Ghafoor, FCPS (1) · Tristen Inagaki, PhD (1)
PMID 30937241, PMID 34781989, PMID 35410938, PMID 38258677, PMID 38966963
2019 (1), R01AA030568 (1), R01DA052883 (1), R01MH133553 (1)