MVAp53 vaccine: Clinical Trials

4 trials of MVAp53 vaccine, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

2 active not recruiting, 2 completed. 3 Phase 1, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 13Completed 2, Active not recruiting 1
Phase 21Active not recruiting 1

Follow MVAp53 vaccine: new trials by email Literature Review of MVAp53 vaccine trials Research Report on MVAp53 vaccine

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
P53MVA and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Modified Vaccinia Virus Ankara Vaccine Expressing p53, Pembrolizumab - Recurrent Platinum-Resistant Fallopian Tube Carcinoma, Recurrent Platinum-Resistant Ovarian Carcinoma
Phase 2Active not recruitingCity of Hope Medical Center292019-05-012026-11-03
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy
Laboratory Biomarker Analysis, Modified Vaccinia Virus Ankara Vaccine Expressing p53, Pembrolizumab - Adult Solid Neoplasm, Bladder Carcinoma
Phase 1Active not recruitingCity of Hope Medical Center112015-12-282026-10-19
p53MVA Vaccine and Gemcitabine Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer
modified vaccinia virus ankara vaccine expressing p53, gemcitabine hydrochloride, laboratory biomarker analysis - Recurrent Ovarian Epithelial Cancer, Recurrent Fallopian Tube Carcinoma
Phase 1CompletedCity of Hope Medical Center122015-02-062026-10-14
Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer
laboratory biomarker analysis, enzyme-linked immunosorbent assay, flow cytometry - Recurrent Colon Cancer, Recurrent Gastric Cancer
Phase 1CompletedCity of Hope Medical Center122011-12-222026-10-19

Conditions studied

Colonic Neoplasms (2)  ·  Pancreatic Neoplasms (2)  ·  Rectal Neoplasms (2)  ·  Carcinoma, Hepatocellular (1)  ·  Carcinoma, Non-Small-Cell Lung (1)  ·  Carcinoma, Ovarian Epithelial (1)  ·  Carcinoma, Renal Cell (1)  ·  Fallopian Tube Neoplasms (1)  ·  Melanoma (1)  ·  Sarcoma (1)  ·  Squamous Cell Carcinoma of Head and Neck (1)  ·  Stomach Neoplasms (1)  ·  Triple Negative Breast Neoplasms (1)  ·  Urinary Bladder Neoplasms (1)

Sponsors

City of Hope Medical Center (4)

Countries

United States (4)

Top investigators

Mihaela Cristea (1)  ·  Thanh Dellinger (1)  ·  Vincent Chung (1)  ·  Vincent Chung, MD (1)

Results publications

PMID 24987057

NIH funding

P30CA033572 (1)