3 completed, 3 terminated. 2 Phase 1, 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 2 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
| Phase 3 | 2 | Terminated 2 |
Follow murepavadin: new trials by email Literature Review of murepavadin trials Research Report on murepavadin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pivotal Study in Nosocomial Pneumonia Suspected or Confirmed to be Due to Pseudomonas Murepavadin, One anti-pseudomonal antibiotic - Pneumonia | Phase 3 | Terminated | Polyphor Ltd. | 2 | 2018-10-22 | 2019-08-28 |
| Pivotal Study in VAP Suspected or Confirmed to be Due to Pseudomonas Aeruginosa Murepavadin, Two anti-pseudomonal antibiotics - Pneumonia | Phase 3 | Terminated | Polyphor Ltd. | 41 | 2018-03-23 | 2019-08-28 |
| DDI Study to Investigate Interaction Between Amikacin and POL7080 POL7080, Amikacin, POL7080 + Amikacin - Healthy | Phase 1 | Completed | Polyphor Ltd. | 14 | 2016-04-01 | 2017-02-01 |
| Safety, Efficacy and PK/PD of POL7080 in Patients With Exacerbation of Non-cystic Fibrosis Bronchiectasis. POL7080 - Bronchiectasis, Lower Respiratory Infection | Phase 2 | Terminated | Polyphor Ltd. | 20 | 2013-12-01 | 2017-02-01 |
| Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia POL7080 - Ventilator Associated Pneumonia, Lower Respiratory Infection | Phase 2 | Completed | Polyphor Ltd. | 25 | 2013-10-01 | 2017-11-28 |
| Pharmacokinetics and Safety of POL7080 in Patients With Renal Impairment POL7080 - Renal Impairment | Phase 1 | Completed | Polyphor Ltd. | 48 | 2013-04-01 | 2016-06-17 |
Pneumonia (2) · Pseudomonas Infections (2) · Bronchiectasis (1) · Healthcare-Associated Pneumonia (1) · Pneumonia, Ventilator-Associated (1) · Renal Insufficiency (1)
Polyphor Ltd. (6)
Spain (3) · France (2) · Germany (2) · Greece (2) · Israel (2) · United States (2) · Brazil (1) · Croatia (1) · Czechia (1) · Estonia (1) · Hungary (1) · Mexico (1) · South Africa (1) · South Korea (1) · Thailand (1)
Adam Hill, MD PhD (1) · Antoni Torres, MD PhD (1) · Atef Halabi, MD (1) · Eva Polverino, MD (1) · Evangelos Giamarellos-Bourboulis, MD PhD (1)