Molecular Targeted Therapy: Clinical Trials

5 trials of Molecular Targeted Therapy, newest first

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3 completed, 1 terminated, 1 unknown. 3 Phase 2, 1 Early Phase 1.

By phase and status

PhaseTrialsStatus
Phase 23Completed 1, Terminated 1, Unknown 1
Early Phase 11Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
The Role of Brain Radiotherapy in Patients With Asymptomatic Brain Metastasis in the Era of Targeted Therapy for NSCLC
molecular targeted therapies, Brain Radiotherapy - Non Small Cell Lung Cancer, Brain Metastases
Phase 2UnknownSecond Affiliated Hospital of Nanchang University1002019-12-012019-12-10
Trajectory-Based Prognostic Modeling in Hepatocellular Carcinoma
Molecular Targeted Therapy (TKI / anti-VEGF antibody) PD-(L)1 Inhibitor Immunotherapy Interventional Therapy (TACE / HAIC) - Liver Cancer
CompletedXu Yong, MD3792018-01-012025-10-02
NU-0129 in Treating Patients With Recurrent Glioblastoma or Gliosarcoma Undergoing Surgery
Laboratory Biomarker Analysis, Pharmacological Study, Targeted Molecular Therapy - Gliosarcoma, Recurrent Glioblastoma
Early Phase 1CompletedNorthwestern University82017-05-252022-08-26
Targeted Therapy in Treating Patients With Incurable Non-Small Cell Lung Cancer With Genetic Mutations
Chemotherapy, Immunotherapy, Laboratory Biomarker Analysis - EGFR Activating Mutation, Recurrent Non-Small Cell Lung Carcinoma
Phase 2TerminatedWake Forest University Health Sciences192017-03-102024-06-28
Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic
cytology specimen collection procedure, MEK 162 therapy or molecularly targeted therapy, therapeutic procedure - Recurrent Melanoma, Stage IIIA Melanoma
Phase 2CompletedYale University492014-05-012020-01-02

Conditions studied

Carcinoma, Non-Small-Cell Lung (2)  ·  Brain Neoplasms (1)  ·  Glioblastoma (1)  ·  Gliosarcoma (1)  ·  Liver Neoplasms (1)  ·  Melanoma (1)

Sponsors

Northwestern University (1)  ·  Second Affiliated Hospital of Nanchang University (1)  ·  Wake Forest University Health Sciences (1)  ·  Xu Yong, MD (1)  ·  Yale University (1)

Countries

United States (3)  ·  China (2)

Top investigators

Liu Anwen, Phd (1)  ·  Patricia LoRusso, D.O. (1)  ·  Priya Kumthekar, MD (1)  ·  William Petty (1)  ·  Yong Xu, Dr (1)

Results publications

PMID 11452123, PMID 12750523, PMID 16757720, PMID 17229875, PMID 19801201, PMID 21041710, PMID 21472002, PMID 22012633, PMID 22134072, PMID 23129122, PMID 24021541, PMID 24419416, PMID 26148750, PMID 26823294, PMID 27343440, PMID 27458945, PMID 28126333

NIH funding

P30CA012197 (1), P30CA022453 (1), P30CA060553 (1)