28 completed. 28 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 28 | Completed 28 |
| Phase 2 | 7 | Completed 7 |
Follow Mitomycin: new trials by email Literature Review of Mitomycin trials Research Report on Mitomycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer UGN-103 - Bladder Cancer, Urothelial Carcinoma | Phase 3 | Completed | UroGen Pharma Ltd. | 99 | 2024-08-29 | 2026-10-22 |
| Intralesional Injection of Mitomycin C Following Visual Internal Urethrotomy for Recurrent Urethral Stricture Mitomycin c - Urethral Stricture | Phase 2 / Phase 3 | Completed | Ain Shams University | 50 | 2022-01-01 | 2024-01-30 |
| Feasibility of Home Instillation of UGN-102 for Treatment of Low-Grade (LG) Non-Muscle Invasive Bladder Cancer (NMIBC) UGN-102 - Bladder Cancer, Urothelial Carcinoma | Phase 3 | Completed | UroGen Pharma Ltd. | 8 | 2021-11-30 | 2024-09-19 |
| The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study UGN-101 instillations - Carcinoma, Transitional Cell, Transitional Cell Carcinoma of Renal Pelvis | Phase 3 | Completed | UroGen Pharma Ltd. | 71 | 2017-04-04 | 2020-12-22 |
| The Bladder Instillation Comparison Study Mitomycin C, Gemcitabine - Urinary Bladder Neoplasms | Phase 3 | Completed | Corewell Health West | 101 | 2016-04-19 | 2023-04-21 |
| Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitis Mitomicin C, Identical placebo solution - Chronic Rhinosinusitis, Postoperative Nasal Synerchia | Phase 3 | Completed | Mahidol University | 224 | 2015-03-01 | 2018-05-23 |
| Bevacizumab Versus Mitomycin C as Trabeculectomy Adjuvant in Uncontrolled Glaucoma Standard Guarded Trabeculectomy, Mitomycin C, Bevacizumab - Glaucoma | Phase 2 / Phase 3 | Completed | Athens Vision Eye Institute | 40 | 2014-01-01 | 2016-09-15 |
| Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome Bevacizumab, Mitomycin C - Glaucoma | Phase 2 / Phase 3 | Completed | Prince of Songkla University | 39 | 2010-12-01 | 2014-01-31 |
| Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery Cisplatin, Computed Tomography, Doxorubicin Hydrochloride - Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma | Phase 3 | Completed | National Cancer Institute (NCI) | 235 | 2009-10-28 | 2024-01-03 |
| Lucentis Versus Mitomycin C During Glaucoma Surgery Ranibizumab, Mitomycin (MMC) - Glaucoma | Phase 2 / Phase 3 | Completed | Wills Eye | 24 | 2008-01-01 | 2018-03-22 |
| Ologen (OculusGen)-Glaucoma MMC Control in Pakistan ologen collagen matrix in glaucoma filtering surgery, MMC in glaucoma filtering surgery - Glaucoma, Trabeculectomy | Phase 3 | Completed | Pro Top & Mediking Company Limited | 40 | 2007-03-01 | 2011-10-07 |
| The MAX Study: Mitomycin C, Avastin and Xeloda in Patients With Untreated Metastatic Colorectal Cancer Mitomycin C; Capecitabine; Bevacizumab - Metastatic Colorectal Cancer | Phase 2 / Phase 3 | Completed | Australasian Gastro-Intestinal Trials Group | 333 | 2005-06-01 | 2007-08-22 |
| Trabeculectomy With MMC Versus Ahmed Glaucoma Implant for Treatment of Pediatric Aphakic Glaucoma trabeculectomy with mitomycin-C - Pediatric Aphakic Glaucoma | Phase 2 / Phase 3 | Completed | Shahid Beheshti University of Medical Sciences | 2004-03-01 | 2006-10-09 | |
| Active Symptom Control With or Without Chemotherapy in Treating Patients With Malignant Pleural Mesothelioma cisplatin, mitomycin C, vincristine sulfate - Malignant Mesothelioma | Phase 3 | Completed | Medical Research Council | 840 | 2003-09-01 | 2013-08-07 |
| Randomized Phase III-Study in Stage IIIb and IV Non-Small-Cell Lung Cancer. Sequential Single-Agent vs. Double-Agent vs. Triple-Agent Therapy. Gemcitabine, Navelbine, Carboplatin - Non-Small-Cell Lung Carcinoma | Phase 3 | Completed | Aktion Bronchialkarzinom e.V. | 280 | 2002-06-01 | 2008-04-22 |
| Trial of Adjuvant Chemotherapy for Gastric Cancer Mitomycin, doxifluridine and cisplatin, Mitomycin and doxifluridine - Stomach Cancer | Phase 3 | Completed | Asan Medical Center | 855 | 2002-02-01 | 2014-02-27 |
| Trial of Adjuvant Chemotherapy for Gastric Cancer cisplatin, mitomycin-C, doxifluridine - Stomach Cancer | Phase 3 | Completed | Asan Medical Center | 528 | 2001-10-01 | 2020-01-18 |
| Radiation Therapy With or Without Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer fluorouracil, mitomycin C, radiation therapy - Bladder Cancer | Phase 3 | Completed | University Hospital Birmingham | 350 | 2001-06-01 | 2013-12-18 |
| Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer cisplatin, fluorouracil, mitomycin C - Anal Cancer | Phase 3 | Completed | University College London (UCL) Cancer Institute | 600 | 2001-03-01 | 2013-08-26 |
| Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer cisplatin, fluorouracil, mitomycin C - Anal Cancer | Phase 3 | Completed | Radiation Therapy Oncology Group | 682 | 1998-10-01 | 2017-01-04 |
Showing 20 of 28. Sign in to see all of them.
Urinary Bladder Neoplasms (6) · Non-Muscle Invasive Bladder Neoplasms (5) · Glaucoma (4) · Carcinoma, Transitional Cell (3) · Anal Canal Carcinoma (2) · Anus Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Stomach Neoplasms (2) · Breast Neoplasms (1) · Carcinoma (1) · Carcinoma, Hepatocellular (1) · Colorectal Neoplasms (1) · Head and Neck Neoplasms (1) · Lung Neoplasms (1) · Mesothelioma, Malignant (1)
Medical Research Council (3) · University of Rome Tor Vergata (3) · UroGen Pharma Ltd. (3) · Asan Medical Center (2) · University Hospital Birmingham (2) · Ain Shams University (1) · Aktion Bronchialkarzinom e.V. (1) · Athens Vision Eye Institute (1) · Australasian Gastro-Intestinal Trials Group (1) · Corewell Health West (1) · European Organisation for Research and Treatment of Cancer - EORTC (1) · Mahidol University (1) · National Cancer Institute (NCI) (1) · Prince of Songkla University (1) · Pro Top & Mediking Company Limited (1)
United States (8) · United Kingdom (7) · Italy (3) · South Korea (2) · Thailand (2) · Australia (1) · Bulgaria (1) · Egypt (1) · Estonia (1) · Georgia (1) · Germany (1) · Iran (1) · Israel (1) · Latvia (1) · New Zealand (1)
Savino M Di Stasi, MD, PhD (3) · Yoon-Koo Kang, M.D.,Ph.D. (2) · Adrian Hodson (1) · Al B Benson (1) · Al B. Benson, MD, FACP (1) · Brian R Lane, MD (1) · Gerassimos Kopsinis, M.D., Ph.D. (1) · Ian E. Smith, MD (1) · Indy Fernando, MD (1) · Jaffer A. Ajani, MD (1) · James J. Fischer, MD, PhD (1) · Jan B. Vermorken, MD, PhD (1) · Joao P Zambon, MD (1) · Joel E. Tepper, MD (1) · John S. MacDonald, MD (1)
PMID 10937547, PMID 16389183, PMID 17122118, PMID 17544497, PMID 18430910, PMID 18486741, PMID 19139424, PMID 20564111, PMID 21831711, PMID 22512481, PMID 23150707, PMID 25019269, PMID 25954110, PMID 30247524, PMID 31785830, PMID 32631491, PMID 32670424, PMID 33539743, PMID 33677615, PMID 34125951, PMID 36912740, PMID 37012180, PMID 39561384
U10CA021115 (1), U10CA180820 (1)