4 recruiting, 2 unknown, 1 completed. 3 Phase 1, 2 Phase 2, 1 Not applicable, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 2, Unknown 1 |
| Phase 2 | 2 | Recruiting 1, Unknown 1 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Microbubbles: new trials by email Literature Review of Microbubbles trials Research Report on Microbubbles
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients Bevacizumab, Microbubble, Low-Intensity Focused Ultrasound - Glioblastoma Multiforme, Glioblastoma | Phase 3 | Recruiting | NaviFUS Corporation | 32 | 2024-11-08 | 2026-04-09 |
| Novel Magnetic Resonance Imaging-Guided Ultrasound-Stimulated Microbubble Radiation Treatment for Patients With Chest-Wall and Breast Cancer Definity, Sonalleve Focused Ultrasound Device - Breast Cancer | Phase 2 | Recruiting | Sunnybrook Health Sciences Centre | 200 | 2024-07-25 | 2024-09-27 |
| MRI-Guided Ultrasound Stimulated Microbubbles Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer MR-Guided Focused Ultrasound Technology, Definity Suspension for Injection - Breast Cancer | Phase 1 | Recruiting | Sunnybrook Health Sciences Centre | 30 | 2024-07-01 | 2024-10-09 |
| Effect of Ultrasound Combined With Microbubbles on Blood Perfusion in Invasive Breast Cancer ultrasound combined with microbubbles - Invasive Breast Cancer, Cavitation | Unknown | Beijing Friendship Hospital | 30 | 2022-09-29 | 2023-12-06 | |
| Medical Imaging and Focused Ultrasound Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI) Harmonic motion imaging guided focused ultrasound (HMIgFUS), Microbubble-mediated Low Intensity Focused Ultrasound (LIFU), Microbubbles - Fibroadenoma, Breast Cancer Stage I | Phase 1 | Recruiting | Columbia University | 82 | 2022-01-19 | 2026-08-13 |
| Microvascular Recovery With Ultrasound in Myocardial Infarction (MRUSMI) Post PCI Trial percutaneous intervention (PCI), Microbubbles, Ultrasound - STEMI, Chest Pain | Not applicable | Completed | University of Nebraska | 50 | 2018-09-16 | 2023-10-31 |
| Assessment of the Changes in Cortical and Medullary Renal Blood Flow During Exercise in Healthy Subjects Using Contrast Enhanced Ultrasound Definity, Exercise, Kidney Ultrasound - Healthy, Physiology | Phase 1 / Phase 2 | Unknown | University of Virginia | 19 | 2016-01-01 | 2017-05-12 |
Breast Neoplasms (3) · Brain Neoplasms (1) · Carcinoma, Ductal, Breast (1) · Chest Pain (1) · Fibroadenoma (1) · Glioblastoma (1) · Glioma (1) · Neoplasms (1) · Neoplasms, Nerve Tissue (1) · ST Elevation Myocardial Infarction (1)
Sunnybrook Health Sciences Centre (2) · Beijing Friendship Hospital (1) · Columbia University (1) · NaviFUS Corporation (1) · University of Nebraska (1) · University of Virginia (1)
Canada (2) · United States (2) · Brazil (1) · China (1) · Netherlands (1) · Taiwan (1)
Bret Taback, MD (1) · Dr. Gregory Czarnota, MD, Ph.D. (1) · Gregory Czarnota, MD, PhD. (1) · Kambiz Kalantarinia, MD (1) · Thomas R Porter, MD (1)
R01CA228275 (1), R01CA301199 (1)