16 completed, 4 unknown, 1 not yet recruiting, 1 terminated. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Completed 16, Unknown 4, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Mercaptopurine: new trials by email Literature Review of Mercaptopurine trials Research Report on Mercaptopurine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunosuppressant Discontinuation in Elderly Patients With Ulcerative Colitis And Long-term Remission Discontinuation of thiopurines. - Ulcerative Colitis (UC) | Phase 4 | Not yet recruiting | Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa | 304 | 2026-05-01 | 2026-04-15 |
| Reduce Risk for Crohn's Disease Patients Methotrexate, Adalimumab, Azathioprine / 6 Mercaptopurine - Crohn's Disease | Phase 4 | Completed | PIBD-Net | 192 | 2017-02-28 | 2025-01-31 |
| A proSpective Randomized Controlled Trial comParing infliximAb-antimetabolites Combination Therapy to Anti-metabolites monotheRapy and Infliximab monothErapy in Crohn's Disease Patients in Sustained Steroid-free Remission on Combination Therapy INFLIXIMAB, AZATHIOPRINE, MERCAPTOPURINE - Crohn's Disease | Phase 4 | Completed | Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives | 211 | 2015-10-09 | 2022-08-03 |
| Thiopurine Induced Pancreatitis in IBD Patients Azathioprine - Pancreatitis, Inflammatory Bowel Diseases | Phase 4 | Withdrawn | Shaare Zedek Medical Center | 2015-03-01 | 2021-03-18 | |
| Determinants of Mercaptopurine Toxicity in Paediatric Acute Lymphoblastic Leukemia Maintenance Therapy Mercaptopurine - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Shandong University | 500 | 2015-01-01 | 2019-04-23 |
| Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid Xaluprine, Puri-Nethol - Acute Lymphoblastic Leukemia, 6-mercaptopurine Therapy | Phase 4 | Unknown | Kjeld Schmiegelow | 16 | 2013-06-01 | 2018-04-20 |
| Comparison of 2 Immunomodulator Withdrawal Schemes for Infliximab Monotherapy in Active Pediatric Crohn's Disease After Thiopurine Failure AZATHIOPRINE or METHOTREXATE - Crohn's Disease | Phase 4 | Terminated | Prof. Arie Levine | 20 | 2013-02-01 | 2015-12-22 |
| A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia ATO, RIF, ATRA - Childhood Acute Promyelocytic Leukemia | Phase 4 | Completed | South China Children's Leukemia Group | 176 | 2011-09-01 | 2022-05-10 |
| Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia Cyclophosphamide, Doxorubicin, Vincristine - Acute Lymphoblastic Leukemia | Phase 4 | Completed | Ruijin Hospital | 100 | 2010-12-01 | 2014-05-20 |
| Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study Prednisolone, Dexamethasone, L-Asparaginase - Acute Lymphoblastic Leukemia (ALL) | Phase 4 | Unknown | National University Hospital, Singapore | 500 | 2008-10-01 | 2016-09-30 |
| The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia 6-mercaptopurine, Methotrexate, 6-mercaptopurine, Methotrexate, Vincristine, Dexamethasone - Acute Lymphoblastic Leukemia | Phase 4 | Unknown | Sun Yat-sen University | 600 | 2008-07-01 | 2010-03-08 |
| Pethema LAL-RI/2008: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia Vincristine, Daunorubicin, Prednisone - Acute Lymphobkastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 107 | 2008-01-01 | 2020-03-05 |
| German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults Dexamethasone/Prednisolone, Cyclophosphamide, Vincristine - Lymphoma, Lymphoblastic | Phase 4 | Completed | Johann Wolfgang Goethe University Hospital | 75 | 2004-04-01 | 2010-08-23 |
| Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab Cyclophosphamide, Dexamethasone / Prednisolone, Vincristine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Johann Wolfgang Goethe University Hospital | 60 | 2004-04-01 | 2010-08-23 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003) Cyclophosphamide, Dexamethasone, Vincristine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 1883 | 2003-04-01 | 2022-08-18 |
| Treatment of High Risk Adult Acute Lymphoblastic Leukemia Vincristine, Daunorubicin, Prednisone - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 100 | 2003-01-01 | 2020-04-07 |
| German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Cyclophosphamide, Dexamethasone / Prednisolone, Cytarabine - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 377 | 2003-01-01 | 2023-03-20 |
| LAL-BR/2001: Study Treatment to Low Risk ALL Prednisone, Vincristine, Daunorubicin - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 150 | 2001-06-01 | 2016-01-20 |
| LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive Vincristine, Daunorubicin, Prednisone - Acute Lymphoblastic Leukemia | Phase 4 | Completed | PETHEMA Foundation | 100 | 2000-01-01 | 2010-01-05 |
| German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99) Dexamethasone / Prednisolone, Cyclophosphamide, Methotrexate - Adult Acute Lymphocytic Leukemia | Phase 4 | Completed | Goethe University | 225 | 1999-10-01 | 2023-03-20 |
Showing 20 of 23. Sign in to see all of them.
Precursor Cell Lymphoblastic Leukemia-Lymphoma (16) · Crohn Disease (4) · Neoplasm, Residual (3) · Colitis, Ulcerative (2) · Arthritis, Rheumatoid (1) · Inflammatory Bowel Diseases (1) · Lymphoma (1) · Pancreatitis (1)
Goethe University (5) · PETHEMA Foundation (5) · Johann Wolfgang Goethe University Hospital (2) · Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives (1) · Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (1) · Kjeld Schmiegelow (1) · National University Hospital, Singapore (1) · PIBD-Net (1) · Prof. Arie Levine (1) · Ruijin Hospital (1) · Shaare Zedek Medical Center (1) · Shandong University (1) · South China Children's Leukemia Group (1) · Sun Yat-sen University (1)
Germany (7) · Spain (5) · China (3) · France (2) · Israel (2) · Australia (1) · Belgium (1) · Denmark (1) · Malaysia (1) · Singapore (1)
Dieter Hoelzer, MD,PhD (4) · Dieter Hoelzer, MD, PhD (2) · Aharon Lerner, MD (1) · Allen Yeoh, MBBS (1) · Arie Levine, MD (1) · Avi On, MD (1) · Baruch Yerushalmi, MD (1) · Bastida Pilar, Dr (1) · Batia Weiss, MD (1) · Changgang Li, M.D. (1) · Dan Turner, MD, PhD (1) · David Laharie (1) · Dieter Hoelzer, MD (1) · Dongbo Lai, M.D. (1)
PMID 19144982, PMID 22442346, PMID 22493293, PMID 23024237, PMID 27561722, PMID 28751559, PMID 24752047, PMID 30044693, PMID 32519032, PMID 32611737, PMID 33248096, PMID 33492239, PMID 35760920, PMID 36640794, PMID 37276496, PMID 39134391, PMID 39781038, PMID 42477805